Sectors & IndustriesHealthcareBiotechnology
Best Biotech Stocks to Buy Now (2025)
Top biotech stocks in 2025 ranked by overall Zen Rating. "A" Rated stocks have returned an average of +32.52% per year, and are the best biotech stocks to buy now. Learn More.

Industry: Biotechnology
F
Biotech is Zen Rated F and is the 132nd ranked industry out of 145 stock market industries
Learn how the Zen Ratings work
Ticker
Company
Zen Rating
Sentiment
Market Cap
Shares
Institutional %
Insider %
Net Insider (L12M)
Net Insider (L3M)
MDXG
MIMEDX GROUP INC
$1.00B148,102,15946.43%53.57%Net BuyingNet Selling
INCY
INCYTE CORP
$20.04B196,322,70377.65%22.35%Net SellingNet Selling
AUPH
AURINIA PHARMACEUTICALS INC
$2.07B131,840,55949.62%12.61%Net Buying
ONC
BEONE MEDICINES LTD
$38.52B1,438,553,2632.29%32.11%Net SellingNet Selling
INVA
INNOVIVA INC
$1.57B74,769,06260.33%39.67%Net SellingNet Buying
JAZZ
JAZZ PHARMACEUTICALS PLC
$10.75B60,765,11628.03%71.97%Net SellingNet Selling
BCRX
BIOCRYST PHARMACEUTICALS INC
$1.47B210,543,22483.87%16.13%Net SellingNet Selling
TVTX
TRAVERE THERAPEUTICS INC
$3.10B89,472,32763.48%36.52%Net SellingNet Selling
FOLD
AMICUS THERAPEUTICS INC
$2.95B308,533,54865.98%34.02%Net SellingNet Selling
MIRM
MIRUM PHARMACEUTICALS INC
$3.65B51,393,57452.21%47.79%Net SellingNet Buying
ALNY
ALNYLAM PHARMACEUTICALS INC
$57.65B132,113,81882.32%17.68%Net SellingNet Selling
EXEL
EXELIXIS INC
$11.40B268,112,15793.42%5.24%Net SellingNet Selling
ANAB
ANAPTYSBIO INC
$1.10B27,688,47042.69%57.31%Net BuyingNet Selling
TBPH
THERAVANCE BIOPHARMA INC
$936.43M50,672,43152.85%47.15%Net SellingNet Selling
HALO
HALOZYME THERAPEUTICS INC
$8.27B117,597,00077.48%22.52%Net SellingNet Selling
ARQT
ARCUTIS BIOTHERAPEUTICS INC
$3.61B122,492,19276.68%23.32%Net SellingNet Selling
RPRX
ROYALTY PHARMA PLC
$22.47B577,238,10756.74%17.42%Net SellingNet Selling
VCYT
VERACYTE INC
$3.48B79,049,17367.80%32.20%Net SellingNet Selling
AKBA
AKEBIA THERAPEUTICS INC
$411.32M265,365,99346.61%7.64%Net Selling
FENC
FENNEC PHARMACEUTICALS INC
$221.56M28,116,8293.87%96.13%Net SellingNet Selling
GYRE
GYRE THERAPEUTICS INC
$727.32M96,333,1571.87%98.13%Net Buying
ZVRA
ZEVRA THERAPEUTICS INC
$484.16M56,297,53570.82%22.18%Net SellingNet Buying
VRTX
VERTEX PHARMACEUTICALS INC
$108.28B253,718,83191.31%1.52%Net SellingNet Selling
RIGL
RIGEL PHARMACEUTICALS INC
$838.86M18,151,34437.74%62.26%Net Selling
IDYA
IDEAYA BIOSCIENCES INC
$2.98B87,666,40892.57%7.43%Net Buying
VCEL
VERICEL CORP
$2.00B50,574,02691.18%8.82%Net SellingNet Selling
SEPN
SEPTERNA INC
$1.14B44,774,19266.24%33.76%Net BuyingNet Selling
IMCR
IMMUNOCORE HOLDINGS PLC
$1.99B50,530,41995.76%4.24%Net BuyingNet Buying
TGTX
TG THERAPEUTICS INC
$5.07B158,759,45157.11%42.89%Net SellingNet Selling
ARGX
ARGENX SE
$56.09B61,034,20250.00%0.00%
NAGE
NIAGEN BIOSCIENCE INC
$549.07M79,806,13918.41%81.59%Net BuyingNet Buying
PTCT
PTC THERAPEUTICS INC
$6.30B80,288,30585.27%14.73%Net SellingNet Selling
KNSA
KINIKSA PHARMACEUTICALS INTERNATIONAL PLC
$3.15B75,795,75953.90%9.39%Net SellingNet Selling
TARS
TARSUS PHARMACEUTICALS INC
$3.38B42,449,10573.35%26.65%Net SellingNet Selling
SLNO
SOLENO THERAPEUTICS INC
$2.42B53,710,02535.66%64.34%Net Selling
ADPT
ADAPTIVE BIOTECHNOLOGIES CORP
$2.84B152,665,18862.07%37.93%Net SellingNet Selling
XERS
XERIS BIOPHARMA HOLDINGS INC
$1.13B165,924,28958.40%14.82%Net SellingNet Buying
PBYI
PUMA BIOTECHNOLOGY INC
$246.41M50,391,10761.29%38.71%Net SellingNet Selling
GMAB
GENMAB A
$19.55B64,206,34995.96%0.00%
LGND
LIGAND PHARMACEUTICALS INC
$3.92B19,681,72028.30%71.70%Net SellingNet Selling
ACAD
ACADIA PHARMACEUTICALS INC
$3.99B169,181,81772.19%27.81%Net SellingNet Selling
APLS
APELLIS PHARMACEUTICALS INC
$2.48B126,525,21876.30%23.70%Net SellingNet Selling
MNKD
MANNKIND CORP
$1.54B307,070,28135.48%64.52%Net SellingNet Selling
LQDA
LIQUIDIA CORP
$2.53B86,995,48350.36%49.64%Net SellingNet Selling
CPRX
CATALYST PHARMACEUTICALS INC
$2.86B122,912,38783.99%15.87%Net BuyingNet Buying
REGN
REGENERON PHARMACEUTICALS INC
$79.44B105,099,46468.34%31.66%Net SellingNet Buying
FBIO
FORTRESS BIOTECH INC
$80.39M31,037,93714.16%48.50%Net BuyingNet Buying
CRMD
CORMEDIX INC
$762.68M78,789,04554.59%8.67%Net SellingNet Selling
FHTX
FOGHORN THERAPEUTICS INC
$261.27M56,551,28972.32%14.11%
SPRO
SPERO THERAPEUTICS INC
$130.14M56,339,29520.07%63.90%Net SellingNet Selling
HRMY
HARMONY BIOSCIENCES HOLDINGS INC
$1.98B57,596,35876.12%23.88%Net SellingNet Selling
BDTX
BLACK DIAMOND THERAPEUTICS INC
$216.50M56,974,91365.78%34.22%Net SellingNet Buying
KRYS
KRYSTAL BIOTECH INC
$6.15B28,997,51978.96%21.04%Net Selling
VRDN
VIRIDIAN THERAPEUTICS INC
$2.90B95,442,00874.98%25.02%Net BuyingNet Buying
BMRN
BIOMARIN PHARMACEUTICAL INC
$10.51B192,114,34493.32%1.74%Net SellingNet Selling
ENTA
ENANTA PHARMACEUTICALS INC
$367.42M28,862,60157.20%42.80%Net Selling
EVAX
EVAXION A
$32.72M315,828,6080.42%0.00%
DOMH
DOMINARI HOLDINGS INC
$70.29M16,012,4357.92%56.79%
TNGX
TANGO THERAPEUTICS INC
$1.35B134,593,99862.83%37.17%Net SellingNet Selling
XOMA
XOMA ROYALTY CORP
$393.16M12,383,10318.97%81.03%Net SellingNet Selling
BNTX
BIONTECH SE
$22.99B240,455,45020.90%0.00%
LXRX
LEXICON PHARMACEUTICALS INC
$486.95M363,398,68021.46%78.54%Net Selling
ZYME
ZYMEWORKS INC
$1.80B74,836,53452.65%47.35%Net Buying
SABS
SAB BIOTHERAPEUTICS INC
$188.05M47,606,85135.08%64.92%Net BuyingNet Buying
PRLD
PRELUDE THERAPEUTICS INC
$104.99M62,865,27043.21%52.21%Net BuyingNet Selling
ARWR
ARROWHEAD PHARMACEUTICALS INC
$5.59B138,257,55080.27%9.95%Net SellingNet Selling
NBP
NOVABRIDGE BIOSCIENCES
$346.13M188,108,17815.78%0.00%
UTHR
UNITED THERAPEUTICS CORP
$20.44B43,056,59986.69%13.31%Net SellingNet Selling
ATNM
ACTINIUM PHARMACEUTICALS INC
$41.49M31,195,89114.29%85.71%Net Selling
IVVD
INVIVYD INC
$582.81M233,122,83461.79%38.21%Net SellingNet Buying
ASMB
ASSEMBLY BIOSCIENCES INC
$608.96M15,817,14050.56%49.44%Net Buying
ASND
ASCENDIS PHARMA A
$12.86B61,098,156100.00%0.00%
HYPD
HYPERION DEFI INC
$32.47M8,097,6593.65%96.35%
AAPG
ASCENTAGE PHARMA GROUP INTERNATIONAL
$2.67B348,999,3200.03%0.00%
AXSM
AXSOME THERAPEUTICS INC
$7.53B50,412,64061.66%38.34%Net SellingNet Selling
ORMP
ORAMED PHARMACEUTICALS INC
$102.69M39,802,45518.18%53.13%
ARVN
ARVINAS INC
$739.86M64,224,29474.70%25.30%Net SellingNet Buying
FTRE
FORTREA HOLDINGS INC
$1.01B92,400,00099.48%0.52%Net BuyingNet Selling
CLLS
CELLECTIS SA
$339.21M72,325,22911.49%0.00%
MESO
MESOBLAST LTD
$1.97B1,279,967,1870.28%0.00%
NBTX
NANOBIOTIX SA
$1.01B48,236,67111.70%0.00%
MDWD
MEDIWOUND LTD
$218.73M12,821,43344.91%0.00%
ARDX
ARDELYX INC
$1.32B242,974,30641.72%58.28%Net BuyingNet Selling
ATRA
ATARA BIOTHERAPEUTICS INC
$98.64M7,210,23514.04%85.96%Net BuyingNet Selling
CMMB
CHEMOMAB THERAPEUTICS LTD
$16.20M492,409,3200.08%3.44%
CORT
CORCEPT THERAPEUTICS INC
$8.13B105,188,21728.45%71.55%Net SellingNet Selling
ALDX
ALDEYRA THERAPEUTICS INC
$298.41M60,162,77365.19%27.77%Net Selling
VALN
VALNEVA SE
$699.93M162,397,2023.25%0.00%
OKYO
OKYO PHARMA LTD
$79.73M37,610,6760.46%99.54%
ACOG
ALPHA COGNITION INC
$125.02M21,742,10425.95%3.86%Net Buying
KROS
KEROS THERAPEUTICS INC
$529.80M30,466,06979.10%20.90%Net SellingNet Selling
AGEN
AGENUS INC
$143.52M34,008,3496.28%93.72%Net BuyingNet Buying
TECH
BIO-TECHNE CORP
$9.59B155,812,70197.61%2.39%Net BuyingNet Selling
ADMA
ADMA BIOLOGICS INC
$4.09B237,997,76579.66%20.34%Net SellingNet Selling
LXEO
LEXEO THERAPEUTICS INC
$661.27M72,987,32767.62%9.87%Net SellingNet Selling
KZIA
KAZIA THERAPEUTICS LTD
$67.59M809,418,7340.02%2.75%
BBIO
BRIDGEBIO PHARMA INC
$13.13B192,708,81363.42%36.58%Net SellingNet Selling
RLMD
RELMADA THERAPEUTICS INC
$313.13M73,333,62210.55%4.77%Net BuyingNet Buying
NTHI
NEONC TECHNOLOGIES HOLDINGS INC
$114.12M19,474,3038.94%91.06%Net Buying
PYPD
POLYPID LTD
$56.35M15,654,12918.10%0.00%

Biotech Stocks FAQ

What are the best biotech stocks to buy right now in Nov 2025?

According to Zen Ratings, our proprietary rating system that evaluates 115 factors proven to drive growth in stocks and assigns each stock in our system an overall letter grade as well as 7 individual Component Grades for Value, Growth, Momentum, Sentiment, Safety, Financials, and proprietary AI algorithms, the 3 best biotechnology stocks to buy right now are:

1. Mimedx Group (NASDAQ:MDXG)


Mimedx Group (NASDAQ:MDXG) is the #1 top biotech stock out of 622 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Mimedx Group (NASDAQ:MDXG) is: Value: B, Growth: B, Momentum: C, Sentiment: A, Safety: C, Financials: A, and AI: C.

Mimedx Group (NASDAQ:MDXG) has a Due Diligence Score of 42, which is 19 points higher than the biotech industry average of 23.

MDXG passed 13 out of 33 due diligence checks and has strong fundamentals. Mimedx Group has seen its stock lose -26.68% over the past year, overperforming other biotech stocks by 18 percentage points.

Mimedx Group has an average 1 year price target of $12.00, an upside of 77.51% from Mimedx Group's current stock price of $6.76.

Mimedx Group stock has a consensus Strong Buy recommendation according to Wall Street analysts. Of the 1 analyst covering Mimedx Group, 100% have issued a Strong Buy rating, 0% have issued a Buy, 0% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

2. Incyte (NASDAQ:INCY)


Incyte (NASDAQ:INCY) is the #2 top biotech stock out of 622 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Incyte (NASDAQ:INCY) is: Value: A, Growth: C, Momentum: C, Sentiment: B, Safety: C, Financials: B, and AI: B.

Incyte (NASDAQ:INCY) has a Due Diligence Score of 56, which is 33 points higher than the biotech industry average of 23.

INCY passed 18 out of 33 due diligence checks and has strong fundamentals. Incyte has seen its stock return 44.99% over the past year, overperforming other biotech stocks by 90 percentage points.

Incyte has an average 1 year price target of $92.29, a downside of -9.58% from Incyte's current stock price of $102.06.

Incyte stock has a consensus Buy recommendation according to Wall Street analysts. Of the 14 analysts covering Incyte, 57.14% have issued a Strong Buy rating, 0% have issued a Buy, 35.71% have issued a hold, while 7.14% have issued a Sell rating, and 0% have issued a Strong Sell.

3. Aurinia Pharmaceuticals (NASDAQ:AUPH)


Aurinia Pharmaceuticals (NASDAQ:AUPH) is the #3 top biotech stock out of 622 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Aurinia Pharmaceuticals (NASDAQ:AUPH) is: Value: B, Growth: C, Momentum: B, Sentiment: A, Safety: C, Financials: A, and AI: B.

Aurinia Pharmaceuticals (NASDAQ:AUPH) has a Due Diligence Score of 43, which is 20 points higher than the biotech industry average of 23.

AUPH passed 14 out of 33 due diligence checks and has strong fundamentals. Aurinia Pharmaceuticals has seen its stock return 78.79% over the past year, overperforming other biotech stocks by 124 percentage points.

Aurinia Pharmaceuticals has an average 1 year price target of $17.67, an upside of 12.67% from Aurinia Pharmaceuticals's current stock price of $15.68.

Aurinia Pharmaceuticals stock has a consensus Buy recommendation according to Wall Street analysts. Of the 3 analysts covering Aurinia Pharmaceuticals, 33.33% have issued a Strong Buy rating, 33.33% have issued a Buy, 33.33% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

What are the biotech stocks with highest dividends?

Out of 4 biotech stocks that have issued dividends in the past year, the 3 biotech stocks with the highest dividend yields are:

1. Dominari Holdings (NASDAQ:DOMH)


Dominari Holdings (NASDAQ:DOMH) has an annual dividend yield of 12.3%, which is 9 percentage points higher than the biotech industry average of 2.98%.

Dominari Holdings's dividend payout ratio of 8.4% indicates that its high dividend yield is sustainable for the long-term.

2. Royalty Pharma (NASDAQ:RPRX)


Royalty Pharma (NASDAQ:RPRX) has an annual dividend yield of 2.26%, which is -1 percentage points lower than the biotech industry average of 2.98%. Royalty Pharma's dividend payout is stable, having never dropped by more than 10% in the last 10 years. Royalty Pharma's dividend has shown consistent growth over the last 10 years.

Royalty Pharma's dividend payout ratio of 49.4% indicates that its dividend yield is sustainable for the long-term.

3. Bio Techne (NASDAQ:TECH)


Bio Techne (NASDAQ:TECH) has an annual dividend yield of 0.52%, which is -2 percentage points lower than the biotech industry average of 2.98%. Bio Techne's dividend payout is not stable, having dropped more than 10% one times in the last 10 years. Bio Techne's dividend has not shown consistent growth over the last 10 years.

Bio Techne's dividend payout ratio of 64% indicates that its dividend yield is sustainable for the long-term.

Why are biotech stocks up?

Biotech stocks were up 1.65% in the last day, and up 1.74% over the last week. Osr Holdings was the among the top gainers in the biotechnology industry, gaining 23.46% yesterday.

OSR Holdings shares are trading higher after its unit Vaximm entered a non-binding term sheet with BCM Europe to explore a potential exclusive global licensing agreement for its VXM01 oral cancer immunotherapy platform.

What are the most undervalued biotech stocks?

Based on the Valuation rating, one of the 7 components of a stocks overall Zen Ratings grade, which evaluates factors including estimated earnings yield, earnings before interest and taxes/enterprise value, cash flow yield, free cash flow to price, and price-to-earnings growth (PEG ratio), the 3 most undervalued biotech stocks right now are:

1. Harmony Biosciences Holdings (NASDAQ:HRMY)


Harmony Biosciences Holdings (NASDAQ:HRMY) is the most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Harmony Biosciences Holdings has a valuation score of 71, which is 56 points higher than the biotech industry average of 15. It passed 5 out of 7 valuation due diligence checks.

Harmony Biosciences Holdings's stock has gained 3.25% in the past year. It has overperformed other stocks in the biotech industry by 48 percentage points.

2. Puma Biotechnology (NASDAQ:PBYI)


Puma Biotechnology (NASDAQ:PBYI) is the second most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Puma Biotechnology has a valuation score of 43, which is 28 points higher than the biotech industry average of 15. It passed 3 out of 7 valuation due diligence checks.

Puma Biotechnology's stock has gained 68.62% in the past year. It has overperformed other stocks in the biotech industry by 114 percentage points.

3. Exelixis (NASDAQ:EXEL)


Exelixis (NASDAQ:EXEL) is the third most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Exelixis has a valuation score of 57, which is 42 points higher than the biotech industry average of 15. It passed 4 out of 7 valuation due diligence checks.

Exelixis's stock has gained 22.05% in the past year. It has overperformed other stocks in the biotech industry by 67 percentage points.

Are biotech stocks a good buy now?

58.17% of biotech stocks rated by analysts are a strong buy right now. On average, analysts expect biotech stocks to rise by 48.48% over the next year.

3.96% of biotech stocks have a Zen Rating of A (Strong Buy), 5.83% of biotech stocks are rated B (Buy), 46.25% are rated C (Hold), 30.63% are rated D (Sell), and 13.33% are rated F (Strong Sell).

What is the average p/e ratio of the biotechnology industry?

The average P/E ratio of the biotechnology industry is 256.93x.
WallStreetZen does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.

Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.