Sectors & IndustriesHealthcareBiotechnology
Best Biotech Stocks to Buy Now (2026)
Top biotech stocks in 2026 ranked by overall Zen Rating. "A" Rated stocks have returned an average of +32.52% per year, and are the best biotech stocks to buy now. Learn More.

Industry: Biotechnology
F
Biotech is Zen Rated F and is the 134th ranked industry out of 145 stock market industries
Learn how the Zen Ratings work
Ticker
Company
Zen Rating
Sentiment
Market Cap
Shares
Institutional %
Insider %
Net Insider (L12M)
Net Insider (L3M)
PHAR
PHARMING GROUP NV
$1.22B680,308,7350.01%0.00%
MDXG
MIMEDX GROUP INC
$789.38M148,102,15946.43%53.57%Net BuyingNet Selling
BCRX
BIOCRYST PHARMACEUTICALS INC
$1.41B210,543,22483.58%16.42%Net SellingNet Selling
ONC
BEONE MEDICINES LTD
$37.84B1,438,553,2632.29%32.05%Net BuyingNet Selling
AUPH
AURINIA PHARMACEUTICALS INC
$1.95B131,840,55949.82%12.68%Net BuyingNet Selling
JAZZ
JAZZ PHARMACEUTICALS PLC
$10.28B60,765,11628.42%71.58%Net SellingNet Selling
INVA
INNOVIVA INC
$1.47B74,769,06260.33%39.67%Net SellingNet Buying
MIRM
MIRUM PHARMACEUTICALS INC
$4.79B51,393,57452.35%47.65%Net SellingNet Buying
EXEL
EXELIXIS INC
$12.01B268,112,15793.47%5.49%Net SellingNet Selling
VCYT
VERACYTE INC
$3.42B79,049,17367.83%32.17%Net SellingNet Selling
TVTX
TRAVERE THERAPEUTICS INC
$2.53B89,472,32763.49%36.51%Net SellingNet Selling
ALNY
ALNYLAM PHARMACEUTICALS INC
$48.28B132,113,81882.79%17.21%Net SellingNet Selling
RPRX
ROYALTY PHARMA PLC
$22.93B577,238,10756.76%17.30%Net SellingNet Selling
INCY
INCYTE CORP
$20.55B196,322,70377.71%22.29%Net SellingNet Selling
ARQT
ARCUTIS BIOTHERAPEUTICS INC
$3.27B122,492,19276.71%23.29%Net SellingNet Selling
GMAB
GENMAB A
$21.16B64,206,34996.17%0.00%
TBPH
THERAVANCE BIOPHARMA INC
$1.03B50,672,43152.91%47.09%Net SellingNet Selling
FENC
FENNEC PHARMACEUTICALS INC
$216.50M28,116,8293.88%96.12%Net SellingNet Selling
AKBA
AKEBIA THERAPEUTICS INC
$363.55M265,365,99346.61%7.64%Net Selling
SEPN
SEPTERNA INC
$1.18B44,774,19266.24%33.76%Net BuyingNet Selling
NAGE
NIAGEN BIOSCIENCE INC
$494.80M79,806,13918.41%81.59%Net BuyingNet Buying
ANAB
ANAPTYSBIO INC
$1.29B27,688,47042.65%57.35%Net SellingNet Selling
FBIO
FORTRESS BIOTECH INC
$107.39M31,037,93714.16%48.94%Net Buying
RIGL
RIGEL PHARMACEUTICALS INC
$683.22M18,151,34437.73%62.27%Net SellingNet Buying
GYRE
GYRE THERAPEUTICS INC
$799.57M96,333,1571.87%98.13%Net Buying
TGTX
TG THERAPEUTICS INC
$5.01B158,759,45157.06%42.94%Net SellingNet Selling
LGND
LIGAND PHARMACEUTICALS INC
$3.93B19,681,72018.29%81.71%Net SellingNet Selling
HALO
HALOZYME THERAPEUTICS INC
$8.43B117,597,00077.68%22.32%Net SellingNet Selling
MNKD
MANNKIND CORP
$1.75B307,070,28135.50%64.50%Net SellingNet Selling
XERS
XERIS BIOPHARMA HOLDINGS INC
$1.26B165,924,28958.40%14.74%Net SellingNet Selling
HRMY
HARMONY BIOSCIENCES HOLDINGS INC
$2.11B57,596,35876.19%23.81%Net SellingNet Selling
PBYI
PUMA BIOTECHNOLOGY INC
$347.19M50,391,10761.36%38.64%Net SellingNet Selling
TNGX
TANGO THERAPEUTICS INC
$1.68B134,593,99862.73%37.27%Net SellingNet Selling
IDYA
IDEAYA BIOSCIENCES INC
$3.16B87,666,40892.57%7.43%Net Buying
ZVRA
ZEVRA THERAPEUTICS INC
$508.37M56,297,53570.82%22.35%Net SellingNet Selling
FHTX
FOGHORN THERAPEUTICS INC
$343.83M56,551,28972.32%14.11%
CPRX
CATALYST PHARMACEUTICALS INC
$2.97B122,912,38784.02%15.89%Net SellingNet Selling
ACAD
ACADIA PHARMACEUTICALS INC
$4.53B169,181,81772.19%27.81%Net SellingNet Selling
TARS
TARSUS PHARMACEUTICALS INC
$3.02B42,449,10573.40%26.60%Net SellingNet Selling
SPRO
SPERO THERAPEUTICS INC
$132.96M56,339,29520.08%63.90%Net SellingNet Selling
IMCR
IMMUNOCORE HOLDINGS PLC
$1.78B50,530,41995.81%4.19%Net BuyingNet Buying
VRCA
VERRICA PHARMACEUTICALS INC
$73.64M9,490,0359.27%90.73%Net BuyingNet Buying
VRTX
VERTEX PHARMACEUTICALS INC
$117.00B253,718,83191.40%1.51%Net SellingNet Selling
SLNO
SOLENO THERAPEUTICS INC
$2.34B53,710,02535.68%64.32%Net SellingNet Selling
APLS
APELLIS PHARMACEUTICALS INC
$2.65B126,525,21876.30%23.70%Net SellingNet Selling
KNSA
KINIKSA PHARMACEUTICALS INTERNATIONAL PLC
$3.17B75,795,75953.90%9.37%Net SellingNet Selling
REGN
REGENERON PHARMACEUTICALS INC
$78.75B105,099,46468.26%31.74%Net SellingNet Selling
ADPT
ADAPTIVE BIOTECHNOLOGIES CORP
$2.68B152,665,18862.21%37.79%Net SellingNet Selling
PTCT
PTC THERAPEUTICS INC
$6.07B80,288,30585.10%14.90%Net SellingNet Selling
VCEL
VERICEL CORP
$1.91B50,574,02691.18%8.82%Net SellingNet Selling
PRLD
PRELUDE THERAPEUTICS INC
$114.41M62,865,27043.21%52.21%Net Buying
LQDA
LIQUIDIA CORP
$3.48B86,995,48350.19%49.81%Net SellingNet Selling
ARGX
ARGENX SE
$49.83B61,034,20250.00%0.00%
KRYS
KRYSTAL BIOTECH INC
$8.29B28,997,51979.21%20.79%Net SellingNet Selling
BDTX
BLACK DIAMOND THERAPEUTICS INC
$146.43M56,974,91365.77%34.23%Net SellingNet Buying
NBP
NOVABRIDGE BIOSCIENCES
$437.17M265,169,37311.20%0.00%
MESO
MESOBLAST LTD
$2.22B1,279,967,1870.28%0.00%
XOMA
XOMA ROYALTY CORP
$337.69M12,383,10318.93%81.07%Net SellingNet Buying
LXRX
LEXICON PHARMACEUTICALS INC
$566.90M363,398,68021.62%78.38%Net Selling
ZYME
ZYMEWORKS INC
$1.79B74,836,53452.53%47.47%Net BuyingNet Selling
FTRE
FORTREA HOLDINGS INC
$1.57B92,400,00099.48%0.52%Net Buying
ARWR
ARROWHEAD PHARMACEUTICALS INC
$9.18B135,809,55881.72%10.16%Net SellingNet Selling
BMRN
BIOMARIN PHARMACEUTICAL INC
$10.91B192,114,34493.36%1.73%Net SellingNet Selling
DOMH
DOMINARI HOLDINGS INC
$65.65M16,012,4357.92%56.66%Net SellingNet Selling
BNTX
BIONTECH SE
$28.37B240,455,45020.98%0.00%
UTHR
UNITED THERAPEUTICS CORP
$20.23B43,056,59986.71%13.29%Net SellingNet Selling
CGEN
COMPUGEN LTD
$197.37M93,538,56513.31%0.00%
EVAX
EVAXION A
$26.40M315,828,6080.42%0.00%
STTK
SHATTUCK LABS INC
$280.96M63,279,84357.50%23.48%Net BuyingNet Selling
CRMD
CORMEDIX INC
$577.52M78,789,04554.72%8.76%Net SellingNet Selling
ARVN
ARVINAS INC
$809.23M64,224,29474.71%25.29%Net SellingNet Selling
AXSM
AXSOME THERAPEUTICS INC
$9.53B50,412,64061.71%38.29%Net SellingNet Buying
ASMB
ASSEMBLY BIOSCIENCES INC
$416.78M15,817,14050.56%49.44%Net Selling
CTXR
CITIUS PHARMACEUTICALS INC
$16.61M20,762,9173.01%2.72%
ENTA
ENANTA PHARMACEUTICALS INC
$362.80M28,862,60157.21%42.79%Net BuyingNet Selling
KROS
KEROS THERAPEUTICS INC
$579.46M30,466,06979.60%20.40%Net SellingNet Selling
CLLS
CELLECTIS SA
$297.26M72,325,22911.49%0.00%
NBTX
NANOBIOTIX SA
$967.63M48,236,67111.70%0.00%
IVA
INVENTIVA SA
$629.46M95,662,3915.34%0.00%
VRDN
VIRIDIAN THERAPEUTICS INC
$3.08B95,442,00874.98%25.02%Net BuyingNet Buying
IVVD
INVIVYD INC
$515.20M233,122,83461.79%38.21%Net SellingNet Buying
SLN
SILENCE THERAPEUTICS PLC
$268.02M141,701,84813.91%0.09%
ORMP
ORAMED PHARMACEUTICALS INC
$136.92M39,802,45518.18%56.29%
ADMA
ADMA BIOLOGICS INC
$4.13B237,997,76579.67%20.33%Net SellingNet Selling
SABS
SAB BIOTHERAPEUTICS INC
$191.86M47,606,85135.08%64.92%Net Buying
BBIO
BRIDGEBIO PHARMA INC
$15.06B192,708,81363.47%36.53%Net SellingNet Selling
ARDX
ARDELYX INC
$1.94B242,974,30641.73%58.27%Net BuyingNet Selling
AGEN
AGENUS INC
$115.63M34,008,3496.28%93.72%Net BuyingNet Buying
PYPD
POLYPID LTD
$71.85M15,654,12918.10%0.00%
HYFT
MINDWALK HOLDINGS CORP
$93.70M46,157,3128.91%0.00%
IBRX
IMMUNITYBIO INC
$6.82B984,965,17914.52%7.77%Net SellingNet Selling
PTN
PALATIN TECHNOLOGIES INC
$27.77M1,702,6750.00%100.00%Net BuyingNet Selling
LYEL
LYELL IMMUNOPHARMA INC
$511.78M21,218,2170.47%99.53%Net BuyingNet Selling
ERAS
ERASCA INC
$2.85B283,711,80571.43%28.57%Net BuyingNet Buying
ATNM
ACTINIUM PHARMACEUTICALS INC
$41.18M31,195,89114.29%85.71%Net Selling
INBX
INHIBRX BIOSCIENCES INC
$1.09B14,543,73871.92%28.08%Net Selling
PLX
PROTALIX BIOTHERAPEUTICS INC
$166.47M80,421,1819.25%90.75%Net BuyingNet Buying
CGON
CG ONCOLOGY INC
$4.61B80,666,17984.77%15.23%Net BuyingNet Buying
TECH
BIO-TECHNE CORP
$11.12B155,812,70197.61%2.39%Net BuyingNet Selling
ASND
ASCENDIS PHARMA A
$13.24B61,098,156100.00%0.00%

Biotech Stocks FAQ

What are the best biotech stocks to buy right now in Jan 2026?

According to Zen Ratings, our proprietary rating system that evaluates 115 factors proven to drive growth in stocks and assigns each stock in our system an overall letter grade as well as 7 individual Component Grades for Value, Growth, Momentum, Sentiment, Safety, Financials, and proprietary AI algorithms, the 3 best biotechnology stocks to buy right now are:

1. Pharming Group Nv (NASDAQ:PHAR)


Pharming Group Nv (NASDAQ:PHAR) is the #1 top biotech stock out of 611 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Pharming Group Nv (NASDAQ:PHAR) is: Value: B, Growth: B, Momentum: A, Sentiment: A, Safety: C, Financials: B, and AI: C.

Pharming Group Nv (NASDAQ:PHAR) has a Due Diligence Score of 29, which is 5 points higher than the biotech industry average of 24.

PHAR passed 9 out of 33 due diligence checks and has average fundamentals. Pharming Group Nv has seen its stock return 87.64% over the past year, overperforming other biotech stocks by 123 percentage points.

2. Mimedx Group (NASDAQ:MDXG)


Mimedx Group (NASDAQ:MDXG) is the #2 top biotech stock out of 611 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Mimedx Group (NASDAQ:MDXG) is: Value: B, Growth: B, Momentum: C, Sentiment: B, Safety: C, Financials: A, and AI: B.

Mimedx Group (NASDAQ:MDXG) has a Due Diligence Score of 49, which is 25 points higher than the biotech industry average of 24.

MDXG passed 15 out of 33 due diligence checks and has strong fundamentals. Mimedx Group has seen its stock lose -41.68% over the past year, underperforming other biotech stocks by -6 percentage points.

Mimedx Group has an average 1 year price target of $10.67, an upside of 100.13% from Mimedx Group's current stock price of $5.33.

Mimedx Group stock has a consensus Strong Buy recommendation according to Wall Street analysts. Of the 3 analysts covering Mimedx Group, 66.67% have issued a Strong Buy rating, 33.33% have issued a Buy, 0% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

3. Biocryst Pharmaceuticals (NASDAQ:BCRX)


Biocryst Pharmaceuticals (NASDAQ:BCRX) is the #3 top biotech stock out of 611 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Biocryst Pharmaceuticals (NASDAQ:BCRX) is: Value: B, Growth: A, Momentum: C, Sentiment: B, Safety: C, Financials: B, and AI: C.

Biocryst Pharmaceuticals (NASDAQ:BCRX) has a Due Diligence Score of 15, which is -9 points lower than the biotech industry average of 24. Although this number is below the industry average, our proven quant model rates BCRX as a "A".

BCRX passed 5 out of 33 due diligence checks and has weak fundamentals. Biocryst Pharmaceuticals has seen its stock lose -11.7% over the past year, overperforming other biotech stocks by 24 percentage points.

Biocryst Pharmaceuticals has an average 1 year price target of $23.33, an upside of 247.22% from Biocryst Pharmaceuticals's current stock price of $6.72.

Biocryst Pharmaceuticals stock has a consensus Buy recommendation according to Wall Street analysts. Of the 6 analysts covering Biocryst Pharmaceuticals, 33.33% have issued a Strong Buy rating, 50% have issued a Buy, 16.67% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

What are the biotech stocks with highest dividends?

Out of 5 biotech stocks that have issued dividends in the past year, the 3 biotech stocks with the highest dividend yields are:

1. Dominari Holdings (NASDAQ:DOMH)


Dominari Holdings (NASDAQ:DOMH) has an annual dividend yield of 24.02%, which is 19 percentage points higher than the biotech industry average of 5.18%.

Dominari Holdings's dividend payout ratio of 8.4% indicates that its high dividend yield is sustainable for the long-term.

2. Oramed Pharmaceuticals (NASDAQ:ORMP)


Oramed Pharmaceuticals (NASDAQ:ORMP) has an annual dividend yield of 7.27%, which is 2 percentage points higher than the biotech industry average of 5.18%.

Oramed Pharmaceuticals's dividend payout ratio of 0% indicates that its high dividend yield might not be sustainable for the long-term.

3. Royalty Pharma (NASDAQ:RPRX)


Royalty Pharma (NASDAQ:RPRX) has an annual dividend yield of 2.22%, which is -3 percentage points lower than the biotech industry average of 5.18%. Royalty Pharma's dividend payout is stable, having never dropped by more than 10% in the last 10 years. Royalty Pharma's dividend has shown consistent growth over the last 10 years.

Royalty Pharma's dividend payout ratio of 49.4% indicates that its dividend yield is sustainable for the long-term.

Why are biotech stocks up?

Biotech stocks were up 1.35% in the last day, and down -0.11% over the last week. Lisata Therapeutics was the among the top gainers in the biotechnology industry, gaining 86.57% yesterday.

Lisata Therapeutics shares are trading higher after the company announced a binding term sheet to be acquired by Kuva Labs for $4.00 per share in an all-cash tender offer.

What are the most undervalued biotech stocks?

Based on the Valuation rating, one of the 7 components of a stocks overall Zen Ratings grade, which evaluates factors including estimated earnings yield, earnings before interest and taxes/enterprise value, cash flow yield, free cash flow to price, and price-to-earnings growth (PEG ratio), the 3 most undervalued biotech stocks right now are:

1. Harmony Biosciences Holdings (NASDAQ:HRMY)


Harmony Biosciences Holdings (NASDAQ:HRMY) is the most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Harmony Biosciences Holdings has a valuation score of 71, which is 55 points higher than the biotech industry average of 16. It passed 5 out of 7 valuation due diligence checks.

Harmony Biosciences Holdings's stock has dropped -9.32% in the past year. It has overperformed other stocks in the biotech industry by 26 percentage points.

2. Innoviva (NASDAQ:INVA)


Innoviva (NASDAQ:INVA) is the second most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Innoviva has a valuation score of 57, which is 41 points higher than the biotech industry average of 16. It passed 4 out of 7 valuation due diligence checks.

Innoviva's stock has gained 4.53% in the past year. It has overperformed other stocks in the biotech industry by 40 percentage points.

3. Puma Biotechnology (NASDAQ:PBYI)


Puma Biotechnology (NASDAQ:PBYI) is the third most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Puma Biotechnology has a valuation score of 43, which is 27 points higher than the biotech industry average of 16. It passed 3 out of 7 valuation due diligence checks.

Puma Biotechnology's stock has gained 131.21% in the past year. It has overperformed other stocks in the biotech industry by 167 percentage points.

Are biotech stocks a good buy now?

62.93% of biotech stocks rated by analysts are a strong buy right now. On average, analysts expect biotech stocks to rise by 54.3% over the next year.

3.09% of biotech stocks have a Zen Rating of A (Strong Buy), 7.41% of biotech stocks are rated B (Buy), 44.65% are rated C (Hold), 34.16% are rated D (Sell), and 10.7% are rated F (Strong Sell).

What is the average p/e ratio of the biotechnology industry?

The average P/E ratio of the biotechnology industry is 170.79x.
WallStreetZen does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.

Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.