Sectors & IndustriesHealthcareBiotechnology
Best Biotech Stocks to Buy Now (2026)
Top biotech stocks in 2026 ranked by overall Zen Rating. "A" Rated stocks have returned an average of +32.52% per year, and are the best biotech stocks to buy now. Learn More.

Industry: Biotechnology
F
Biotech is Zen Rated F and is the 133rd ranked industry out of 145 stock market industries
Learn how the Zen Ratings work
Ticker
Company
Zen Rating
Sentiment
Market Cap
Shares
Institutional %
Insider %
Net Insider (L12M)
Net Insider (L3M)
JAZZ
JAZZ PHARMACEUTICALS PLC
$11.50B61,560,35028.79%71.21%Net SellingNet Selling
INVA
INNOVIVA INC
$1.71B74,073,64660.21%39.79%Net BuyingNet Selling
AUPH
AURINIA PHARMACEUTICALS INC
$2.13B132,970,97954.35%13.23%Net BuyingNet Buying
VCYT
VERACYTE INC
$2.57B79,458,42766.88%33.12%Net SellingNet Selling
BCRX
BIOCRYST PHARMACEUTICALS INC
$2.38B250,800,62083.18%15.21%Net SellingNet Buying
PBYI
PUMA BIOTECHNOLOGY INC
$350.54M50,876,48761.74%38.26%Net Selling
ASMB
ASSEMBLY BIOSCIENCES INC
$463.51M15,862,70552.43%47.57%Net SellingNet Selling
SPRO
SPERO THERAPEUTICS INC
$151.10M57,891,49336.48%62.44%Net SellingNet Selling
EXEL
EXELIXIS INC
$11.42B259,708,68994.72%5.28%Net SellingNet Selling
PHAR
PHARMING GROUP NV
$1.16B701,680,4400.02%0.00%
XERS
XERIS BIOPHARMA HOLDINGS INC
$1.04B172,431,29058.47%14.31%Net SellingNet Selling
TBPH
THERAVANCE BIOPHARMA INC
$829.04M51,492,92453.54%46.46%Net SellingNet Selling
VRTX
VERTEX PHARMACEUTICALS INC
$110.33B254,034,19092.82%1.52%Net SellingNet Selling
MDXG
MIMEDX GROUP INC
$576.44M148,566,58646.84%53.16%Net BuyingNet Buying
GLPG
GALAPAGOS NV
$1.94B65,897,07147.64%0.00%
ARQT
ARCUTIS BIOTHERAPEUTICS INC
$2.93B124,033,38277.21%22.79%Net SellingNet Selling
AGEN
AGENUS INC
$144.76M38,398,3547.15%92.85%Net BuyingNet Buying
RPRX
ROYALTY PHARMA PLC
$27.30B576,856,75361.89%17.27%Net SellingNet Selling
CGEN
COMPUGEN LTD
$206.13M94,553,19113.32%0.32%Net BuyingNet Buying
REGN
REGENERON PHARMACEUTICALS INC
$80.67B105,719,80668.82%31.18%Net SellingNet Selling
ONC
BEONE MEDICINES LTD
$33.59B1,442,259,8102.35%32.03%Net BuyingNet Buying
SLGL
SOL-GEL TECHNOLOGIES LTD
$207.12M2,786,15824.11%75.89%Net BuyingNet Buying
ZVRA
ZEVRA THERAPEUTICS INC
$571.85M58,711,58464.97%21.95%Net SellingNet Selling
XLO
XILIO THERAPEUTICS INC
$48.92M5,782,51153.31%46.69%Net BuyingNet Buying
INCY
INCYTE CORP
$18.88B199,014,48677.98%22.02%Net SellingNet Selling
TVTX
TRAVERE THERAPEUTICS INC
$2.94B92,241,55063.78%36.22%Net SellingNet Selling
STTK
SHATTUCK LABS INC
$485.21M71,564,21758.73%20.75%Net BuyingNet Selling
CPRX
CATALYST PHARMACEUTICALS INC
$3.05B122,123,88484.18%15.82%Net Selling
NAGE
NIAGEN BIOSCIENCE INC
$357.96M80,080,48818.63%81.37%Net Buying
LQDA
LIQUIDIA CORP
$3.32B88,114,42949.44%50.56%Net SellingNet Selling
ADMA
ADMA BIOLOGICS INC
$2.21B238,159,17679.68%20.32%Net SellingNet Selling
VCEL
VERICEL CORP
$1.73B50,763,31991.13%8.87%Net SellingNet Selling
TARS
TARSUS PHARMACEUTICALS INC
$2.99B42,557,49272.94%27.06%Net SellingNet Selling
OMER
OMEROS CORP
$783.68M71,996,17147.11%5.03%Net BuyingNet Buying
BMRN
BIOMARIN PHARMACEUTICAL INC
$10.81B192,323,35997.84%1.79%Net SellingNet Selling
ALNY
ALNYLAM PHARMACEUTICALS INC
$43.81B132,623,14482.36%17.64%Net SellingNet Selling
XOMA
XOMA ROYALTY CORP
$401.82M11,905,65219.43%80.57%Net SellingNet Buying
ENTA
ENANTA PHARMACEUTICALS INC
$384.51M29,019,34464.96%35.04%Net SellingNet Selling
AXSM
AXSOME THERAPEUTICS INC
$8.68B51,153,28962.01%37.99%Net SellingNet Selling
SLNO
SOLENO THERAPEUTICS INC
$2.70B51,624,38435.50%64.50%Net SellingNet Selling
RIGL
RIGEL PHARMACEUTICALS INC
$505.42M18,473,13039.34%60.66%Net SellingNet Selling
LCTX
LINEAGE CELL THERAPEUTICS INC
$383.59M249,087,52939.96%60.04%Net SellingNet Selling
NRXP
NRX PHARMACEUTICALS INC
$74.40M33,067,6309.51%90.49%
ADCT
ADC THERAPEUTICS SA
$466.25M127,044,35660.51%39.49%Net SellingNet Selling
FBIO
FORTRESS BIOTECH INC
$80.83M32,202,56418.24%50.14%Net BuyingNet Buying
KNSA
KINIKSA PHARMACEUTICALS INTERNATIONAL PLC
$3.79B76,535,37756.15%9.31%Net SellingNet Selling
UTHR
UNITED THERAPEUTICS CORP
$24.53B43,827,68686.81%13.19%Net SellingNet Selling
NBP
NOVABRIDGE BIOSCIENCES
$279.14M265,169,37312.52%12.04%
HALO
HALOZYME THERAPEUTICS INC
$7.44B118,017,00078.05%21.95%Net SellingNet Selling
SEPN
SEPTERNA INC
$1.11B44,906,37466.75%33.25%Net BuyingNet Buying
MGTX
MEIRAGTX HOLDINGS PLC
$775.37M81,446,12657.68%42.32%Net SellingNet Selling
IBRX
IMMUNITYBIO INC
$7.28B1,028,111,45616.47%7.45%Net BuyingNet Buying
DOMH
DOMINARI HOLDINGS INC
$64.45M22,613,7816.96%68.39%Net Selling
ADAG
ADAGENE INC
$204.71M59,231,9935.22%1.43%
INSM
INSMED INC
$35.31B215,551,89685.00%15.00%Net SellingNet Selling
ARGX
ARGENX SE
$46.30B61,883,30648.47%0.00%
ORMP
ORAMED PHARMACEUTICALS INC
$139.13M40,446,17927.33%55.88%Net SellingNet Selling
VIR
VIR BIOTECHNOLOGY INC
$1.26B139,517,27869.08%30.92%Net SellingNet Selling
LGND
LIGAND PHARMACEUTICALS INC
$4.06B19,941,14118.32%81.68%Net SellingNet Selling
ADPT
ADAPTIVE BIOTECHNOLOGIES CORP
$2.17B153,981,56162.99%37.01%Net SellingNet Selling
KALV
KALVISTA PHARMACEUTICALS INC
$1.03B51,222,48762.25%37.75%Net SellingNet Selling
DTIL
PRECISION BIOSCIENCES INC
$148.61M24,726,69535.28%64.72%Net SellingNet Selling
CYPH
CYPHERPUNK TECHNOLOGIES INC
$69.28M89,979,6199.59%56.99%Net SellingNet Selling
ASND
ASCENDIS PHARMA A
$13.91B61,380,31299.19%0.81%
QTTB
Q32 BIO INC
$82.51M14,629,46328.18%71.82%Net SellingNet Selling
ABUS
ARBUTUS BIOPHARMA CORP
$871.83M195,478,06830.49%69.51%
AKTS
AKTIS ONCOLOGY INC
$874.21M53,403,1730.00%59.96%Net BuyingNet Buying
ACAD
ACADIA PHARMACEUTICALS INC
$3.81B170,494,61372.02%27.98%Net SellingNet Selling
RLAY
RELAY THERAPEUTICS INC
$2.23B178,725,80978.46%21.54%Net SellingNet Selling
TECH
BIO-TECHNE CORP
$8.42B156,453,29297.79%2.21%Net BuyingNet Selling
KZIA
KAZIA THERAPEUTICS LTD
$416.03M5,667,995,7340.04%0.39%
HRMY
HARMONY BIOSCIENCES HOLDINGS INC
$1.60B57,840,61477.07%22.93%Net SellingNet Selling
FENC
FENNEC PHARMACEUTICALS INC
$221.33M34,475,1784.33%95.67%Net SellingNet Buying
ALMS
ALUMIS INC
$2.79B127,199,33362.16%23.09%Net BuyingNet Buying
PGEN
PRECIGEN INC
$1.48B353,928,67231.78%68.22%Net SellingNet Selling
RCUS
ARCUS BIOSCIENCES INC
$2.79B125,349,47668.34%31.66%Net Selling
VRCA
VERRICA PHARMACEUTICALS INC
$102.73M17,178,78615.89%84.11%Net Buying
PTGX
PROTAGONIST THERAPEUTICS INC
$6.57B63,808,71682.89%17.11%Net SellingNet Selling
MIRM
MIRUM PHARMACEUTICALS INC
$5.81B60,341,61753.72%46.28%Net BuyingNet Buying
ARWR
ARROWHEAD PHARMACEUTICALS INC
$8.56B140,032,19082.92%9.84%Net SellingNet Selling
SLN
SILENCE THERAPEUTICS PLC
$273.68M141,701,84812.77%0.09%
RLYB
RALLYBIO CORP
$42.95M5,289,67538.31%61.69%Net SellingNet Selling
TSHA
TAYSHA GENE THERAPIES INC
$1.34B287,269,88589.42%10.58%Net BuyingNet Selling
NRXS
NEURAXIS INC
$82.90M11,187,63914.06%35.15%Net BuyingNet Buying
CDXS
CODEXIS INC
$171.74M90,869,34946.64%53.36%Net SellingNet Selling
PLYX
POLARYX THERAPEUTICS INC
$271.28M47,343,2970.00%52.80%Net BuyingNet Buying
PRLD
PRELUDE THERAPEUTICS INC
$231.85M63,002,24845.19%52.26%Net Selling
VYGR
VOYAGER THERAPEUTICS INC
$236.61M59,599,37553.24%46.76%Net SellingNet Selling
ANL
ADLAI NORTYE LTD
$331.77M110,700,8030.05%0.00%
ARDX
ARDELYX INC
$1.46B245,247,42742.19%57.81%Net BuyingNet Buying
BEAM
BEAM THERAPEUTICS INC
$2.47B101,856,24586.28%13.72%Net SellingNet Selling
CCCC
C4 THERAPEUTICS INC
$277.12M97,578,17579.95%20.05%Net SellingNet Selling
NTHI
NEONC TECHNOLOGIES HOLDINGS INC
$136.65M23,806,2168.95%78.95%Net Buying
MRVI
MARAVAI LIFESCIENCES HOLDINGS INC
$758.35M257,067,24245.21%54.79%Net BuyingNet Selling
VOR
VOR BIOPHARMA INC
$794.75M48,847,50452.26%30.42%Net SellingNet Selling
KRYS
KRYSTAL BIOTECH INC
$7.65B29,232,18980.01%19.99%Net SellingNet Selling
OBIO
ORCHESTRA BIOMED HOLDINGS INC
$248.13M58,520,90137.08%61.27%Net BuyingNet Selling
PHAT
PHATHOM PHARMACEUTICALS INC
$886.49M78,798,71265.08%34.92%Net SellingNet Selling
LEGN
LEGEND BIOTECH CORP
$3.45B369,886,36923.68%0.15%Net SellingNet Selling
ALLO
ALLOGENE THERAPEUTICS INC
$633.82M243,777,92066.72%31.96%Net SellingNet Selling

Biotech Stocks FAQ

What are the best biotech stocks to buy right now in Apr 2026?

According to Zen Ratings, our proprietary rating system that evaluates 115 factors proven to drive growth in stocks and assigns each stock in our system an overall letter grade as well as 7 individual Component Grades for Value, Growth, Momentum, Sentiment, Safety, Financials, and proprietary AI algorithms, the 3 best biotechnology stocks to buy right now are:

1. Jazz Pharmaceuticals (NASDAQ:JAZZ)


Jazz Pharmaceuticals (NASDAQ:JAZZ) is the #1 top biotech stock out of 606 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Jazz Pharmaceuticals (NASDAQ:JAZZ) is: Value: B, Growth: A, Momentum: B, Sentiment: C, Safety: C, Financials: B, and AI: B.

Jazz Pharmaceuticals (NASDAQ:JAZZ) has a Due Diligence Score of 16, which is -9 points lower than the biotech industry average of 25. Although this number is below the industry average, our proven quant model rates JAZZ as a "A".

JAZZ passed 5 out of 33 due diligence checks and has weak fundamentals. Jazz Pharmaceuticals has seen its stock return 74.74% over the past year, overperforming other biotech stocks by 93 percentage points.

Jazz Pharmaceuticals has an average 1 year price target of $223.91, an upside of 19.83% from Jazz Pharmaceuticals's current stock price of $186.85.

Jazz Pharmaceuticals stock has a consensus Strong Buy recommendation according to Wall Street analysts. Of the 11 analysts covering Jazz Pharmaceuticals, 63.64% have issued a Strong Buy rating, 27.27% have issued a Buy, 9.09% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

2. Innoviva (NASDAQ:INVA)


Innoviva (NASDAQ:INVA) is the #2 top biotech stock out of 606 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Innoviva (NASDAQ:INVA) is: Value: A, Growth: C, Momentum: C, Sentiment: B, Safety: C, Financials: A, and AI: C.

Innoviva (NASDAQ:INVA) has a Due Diligence Score of 56, which is 31 points higher than the biotech industry average of 25.

INVA passed 17 out of 33 due diligence checks and has strong fundamentals. Innoviva has seen its stock return 31.47% over the past year, overperforming other biotech stocks by 50 percentage points.

Innoviva has an average 1 year price target of $37.33, an upside of 62.18% from Innoviva's current stock price of $23.02.

Innoviva stock has a consensus Strong Buy recommendation according to Wall Street analysts. Of the 3 analysts covering Innoviva, 66.67% have issued a Strong Buy rating, 33.33% have issued a Buy, 0% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

3. Aurinia Pharmaceuticals (NASDAQ:AUPH)


Aurinia Pharmaceuticals (NASDAQ:AUPH) is the #3 top biotech stock out of 606 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Aurinia Pharmaceuticals (NASDAQ:AUPH) is: Value: B, Growth: C, Momentum: B, Sentiment: A, Safety: C, Financials: B, and AI: C.

Aurinia Pharmaceuticals (NASDAQ:AUPH) has a Due Diligence Score of 55, which is 30 points higher than the biotech industry average of 25.

AUPH passed 18 out of 33 due diligence checks and has strong fundamentals. Aurinia Pharmaceuticals has seen its stock return 110.8% over the past year, overperforming other biotech stocks by 129 percentage points.

Aurinia Pharmaceuticals has an average 1 year price target of $17.33, an upside of 8.33% from Aurinia Pharmaceuticals's current stock price of $16.00.

Aurinia Pharmaceuticals stock has a consensus Buy recommendation according to Wall Street analysts. Of the 3 analysts covering Aurinia Pharmaceuticals, 33.33% have issued a Strong Buy rating, 0% have issued a Buy, 66.67% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

What are the biotech stocks with highest dividends?

Out of 6 biotech stocks that have issued dividends in the past year, the 3 biotech stocks with the highest dividend yields are:

1. Dominari Holdings (NASDAQ:DOMH)


Dominari Holdings (NASDAQ:DOMH) has an annual dividend yield of 23.33%, which is 19 percentage points higher than the biotech industry average of 4.63%.

Dominari Holdings's dividend payout ratio of -42.4% indicates that its high dividend yield might not be sustainable for the long-term.

2. Oramed Pharmaceuticals (NASDAQ:ORMP)


Oramed Pharmaceuticals (NASDAQ:ORMP) has an annual dividend yield of 7.27%, which is 3 percentage points higher than the biotech industry average of 4.63%.

Oramed Pharmaceuticals's dividend payout ratio of 16.3% indicates that its high dividend yield is sustainable for the long-term.

3. Novo Nordisk (Ozempic) (NYSE:NVO)


Novo Nordisk (Ozempic) (NYSE:NVO) has an annual dividend yield of 3.48%, which is -1 percentage points lower than the biotech industry average of 4.63%. Novo Nordisk (Ozempic)'s dividend payout is not stable, having dropped more than 10% nine times in the last 10 years. Novo Nordisk (Ozempic)'s dividend has shown consistent growth over the last 10 years.

Novo Nordisk (Ozempic)'s dividend payout ratio of 46.1% indicates that its dividend yield is sustainable for the long-term.

Why are biotech stocks down?

Biotech stocks were down -0.18% in the last day, and up 6.31% over the last week. Pmgc Holdings was the among the top losers in the biotechnology industry, dropping -32.87% yesterday.

PMGC Holdings shares are trading lower after the company announced that its subsidiary NorthStrive Defense Tech acquired rights to a novel drone technology through an exclusive option agreement with another corporation.

What are the most undervalued biotech stocks?

Based on the Valuation rating, one of the 7 components of a stocks overall Zen Ratings grade, which evaluates factors including estimated earnings yield, earnings before interest and taxes/enterprise value, cash flow yield, free cash flow to price, and price-to-earnings growth (PEG ratio), the 3 most undervalued biotech stocks right now are:

1. Harmony Biosciences Holdings (NASDAQ:HRMY)


Harmony Biosciences Holdings (NASDAQ:HRMY) is the most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Harmony Biosciences Holdings has a valuation score of 71, which is 57 points higher than the biotech industry average of 14. It passed 5 out of 7 valuation due diligence checks.

Harmony Biosciences Holdings's stock has dropped -2.43% in the past year. It has overperformed other stocks in the biotech industry by 16 percentage points.

2. Incyte (NASDAQ:INCY)


Incyte (NASDAQ:INCY) is the second most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Incyte has a valuation score of 71, which is 57 points higher than the biotech industry average of 14. It passed 5 out of 7 valuation due diligence checks.

Incyte's stock has gained 57.34% in the past year. It has overperformed other stocks in the biotech industry by 76 percentage points.

3. Exelixis (NASDAQ:EXEL)


Exelixis (NASDAQ:EXEL) is the third most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Exelixis has a valuation score of 43, which is 29 points higher than the biotech industry average of 14. It passed 3 out of 7 valuation due diligence checks.

Exelixis's stock has gained 26.23% in the past year. It has overperformed other stocks in the biotech industry by 45 percentage points.

Are biotech stocks a good buy now?

62.23% of biotech stocks rated by analysts are a strong buy right now. On average, analysts expect biotech stocks to rise by 63.75% over the next year.

2.42% of biotech stocks have a Zen Rating of A (Strong Buy), 4.85% of biotech stocks are rated B (Buy), 48.46% are rated C (Hold), 34.14% are rated D (Sell), and 10.13% are rated F (Strong Sell).

What is the average p/e ratio of the biotechnology industry?

The average P/E ratio of the biotechnology industry is 28.11x.
WallStreetZen does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.

Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.