Sectors & IndustriesHealthcareBiotechnology
Best Biotech Stocks to Buy Now (2026)
Top biotech stocks in 2026 ranked by overall Zen Rating. "A" Rated stocks have returned an average of +28.50% per year, and are the best biotech stocks to buy now. Learn More.

Industry: Biotechnology
F
Biotech is Zen Rated F and is the 138th ranked industry out of 145 stock market industries
Learn how the Zen Ratings work
Ticker
Company
Zen Rating
Sentiment
Market Cap
Shares
Institutional %
Insider %
Net Insider (L12M)
Net Insider (L3M)
PBYI
PUMA BIOTECHNOLOGY INC
$492.97M51,620,0660.07%42.52%Net SellingNet Selling
CORT
CORCEPT THERAPEUTICS INC
$12.07B108,098,3970.04%99.96%Net BuyingNet Selling
PGEN
PRECIGEN INC
$2.54B358,035,2470.04%81.76%Net SellingNet Selling
HRMY
HARMONY BIOSCIENCES HOLDINGS INC
$2.46B58,236,3930.09%25.53%Net Selling
FENC
FENNEC PHARMACEUTICALS INC
$434.48M35,067,1590.00%100.00%Net SellingNet Selling
ICCC
IMMUCELL CORP
$89.91M9,082,1970.01%21.31%Net BuyingNet Buying
HALO
HALOZYME THERAPEUTICS INC
$12.51B113,498,0000.11%30.26%Net SellingNet Selling
ONC
BEONE MEDICINES LTD
$40.78B1,478,124,4050.00%30.90%Net SellingNet Selling
JAZZ
JAZZ PHARMACEUTICALS PLC
$16.02B64,914,5770.04%99.96%Net SellingNet Selling
PTGX
PROTAGONIST THERAPEUTICS INC
$9.43B64,708,2850.12%22.54%Net SellingNet Buying
VCYT
VERACYTE INC
$3.42B80,390,7310.11%53.43%Net SellingNet Selling
ARQT
ARCUTIS BIOTHERAPEUTICS INC
$3.00B125,691,9610.10%30.69%Net SellingNet Selling
REGN
REGENERON PHARMACEUTICALS INC
$85.22B102,954,9880.09%39.28%Net SellingNet Buying
RPRX
ROYALTY PHARMA PLC
$36.78B575,001,2040.06%18.01%Net SellingNet Selling
ORMP
ORAMED PHARMACEUTICALS INC
$208.40M41,597,3540.04%53.95%Net SellingNet Selling
MGTX
MEIRAGTX HOLDINGS PLC
$1.33B96,042,9960.08%50.23%Net SellingNet Selling
BMRN
BIOMARIN PHARMACEUTICAL INC
$12.88B193,573,7590.10%1.80%Net SellingNet Selling
BCRX
BIOCRYST PHARMACEUTICALS INC
$2.55B255,535,1050.10%15.10%Net SellingNet Buying
EXEL
EXELIXIS INC
$14.62B247,781,6920.10%5.67%Net SellingNet Selling
AUPH
AURINIA PHARMACEUTICALS INC
$2.14B133,051,1680.06%14.08%Net BuyingNet Selling
ZVRA
ZEVRA THERAPEUTICS INC
$736.36M59,383,7810.08%21.68%Net SellingNet Selling
VCEL
VERICEL CORP
$2.06B51,206,6140.11%10.19%Net SellingNet Selling
ACAD
ACADIA PHARMACEUTICALS INC
$4.83B172,305,5180.10%37.54%Net SellingNet Selling
OMER
OMEROS CORP
$1.37B72,388,3160.05%5.73%Net BuyingNet Buying
PTCT
PTC THERAPEUTICS INC
$5.78B83,460,8020.12%18.88%Net SellingNet Selling
ASND
ASCENDIS PHARMA A
$17.77B65,673,2840.10%0.78%Net SellingNet Buying
RLYB
RALLYBIO CORP
$89.88M5,310,4990.01%99.99%Net BuyingNet Buying
ANL
ADLAI NORTYE GROUP LTD
$965.65M193,193,8130.01%9.11%Net SellingNet Selling
ARGX
ARGENX SE
$64.61B62,537,9230.05%0.00%
KNSA
KINIKSA PHARMACEUTICALS INTERNATIONAL PLC
$6.08B78,024,0130.06%10.48%Net SellingNet Selling
PRLD
PRELUDE THERAPEUTICS INC
$435.73M79,803,4850.06%51.13%Net Buying
INCY
INCYTE CORP
$25.69B202,697,7460.10%28.09%Net SellingNet Selling
XERS
XERIS BIOPHARMA HOLDINGS INC
$1.56B182,320,3060.06%13.43%Net SellingNet Selling
FTRE
FORTREA HOLDINGS INC
$1.68B95,100,0000.11%1.15%Net SellingNet Selling
MRVI
MARAVAI LIFESCIENCES HOLDINGS INC
$1.90B259,673,6250.05%60.31%Net SellingNet Selling
LEGN
LEGEND BIOTECH CORP
$4.17B387,538,9230.03%0.15%Net SellingNet Selling
PLX
PROTALIX BIOTHERAPEUTICS INC
$215.13M80,571,6420.01%99.99%Net Buying
ACIU
AC IMMUNE SA
$290.98M101,742,2310.02%4.41%Net Selling
CYPH
CYPHERPUNK TECHNOLOGIES INC
$260.79M107,764,3820.01%94.00%Net BuyingNet Buying
KRYS
KRYSTAL BIOTECH INC
$10.60B29,598,8360.10%25.15%Net SellingNet Selling
SLN
SILENCE THERAPEUTICS PLC
$688.64M141,740,0370.02%0.09%
OABI
OMNIAB INC
$629.54M145,390,3980.04%22.94%Net Selling
RIGL
RIGEL PHARMACEUTICALS INC
$909.15M18,679,8640.07%99.93%Net SellingNet Selling
TARS
TARSUS PHARMACEUTICALS INC
$3.98B43,882,9960.11%39.18%Net SellingNet Selling
GMAB
GENMAB A
$20.95B62,353,2520.16%0.00%
NVO
NOVO NORDISK A S
$206.71B4,435,800,0000.01%0.00%
HOWL
WEREWOLF THERAPEUTICS INC
$46.95M48,599,0660.02%83.87%Net SellingNet Selling
FHTX
FOGHORN THERAPEUTICS INC
$292.18M59,385,3150.08%14.30%
VRTX
VERTEX PHARMACEUTICALS INC
$138.42B253,460,9240.10%1.52%Net SellingNet Selling
INSM
INSMED INC
$27.58B218,381,5030.10%17.37%Net SellingNet Selling
URGN
UROGEN PHARMA LTD
$2.16B48,880,5640.09%20.41%Net SellingNet Selling
ADMA
ADMA BIOLOGICS INC
$2.15B223,984,6800.09%25.11%Net SellingNet Selling
ARMP
ARMATA PHARMACEUTICALS INC
$217.14M37,181,9790.01%99.99%Net SellingNet Selling
ZYME
ZYMEWORKS INC
$2.07B70,959,2410.10%93.89%Net SellingNet Buying
KYMR
KYMERA THERAPEUTICS INC
$9.76B83,150,6180.12%31.95%Net SellingNet Selling
FBIO
FORTRESS BIOTECH INC
$90.71M33,350,9930.02%49.61%Net Buying
ARVN
ARVINAS INC
$613.98M65,386,1910.08%35.29%Net SellingNet Selling
ALNY
ALNYLAM PHARMACEUTICALS INC
$35.61B133,809,1180.10%20.79%Net Selling
SEPN
SEPTERNA INC
$1.72B46,676,9470.10%58.91%Net SellingNet Selling
AVXL
ANAVEX LIFE SCIENCES CORP
$265.11M92,696,8420.04%4.79%Net Buying
VIR
VIR BIOTECHNOLOGY INC
$1.93B169,215,9580.09%30.90%Net Selling
MDGL
MADRIGAL PHARMACEUTICALS INC
$12.50B23,104,1260.04%99.96%Net SellingNet Selling
TVTX
TRAVERE THERAPEUTICS INC
$6.15B94,261,0820.11%61.61%Net SellingNet Selling
KURA
KURA ONCOLOGY INC
$1.18B88,960,6190.10%11.19%Net SellingNet Buying
IOVA
IOVANCE BIOTHERAPEUTICS INC
$3.98B452,971,4320.03%99.97%Net SellingNet Selling
YARW
YARROW BIOSCIENCE INC
$80.65M2,669,7460.05%99.95%Net SellingNet Selling
IMCR
IMMUNOCORE HOLDINGS PLC
$1.86B51,498,6170.10%4.27%Net Selling
MRNA
MODERNA INC
$58.11B399,235,8890.08%24.04%Net BuyingNet Buying
NRXS
NEURAXIS INC
$74.84M12,557,7650.02%35.87%Net BuyingNet Buying
ARDX
ARDELYX INC
$941.93M249,187,5720.07%91.72%Net SellingNet Selling
INVA
INNOVIVA INC
$1.54B72,245,4850.10%69.14%Net BuyingNet Selling
ASMB
ASSEMBLY BIOSCIENCES INC
$745.20M20,360,5960.09%63.58%Net BuyingNet Selling
AGEN
AGENUS INC
$370.97M45,020,4070.01%99.99%Net BuyingNet Buying
RLMD
RELMADA THERAPEUTICS INC
$472.55M106,669,8460.09%3.32%Net Buying
XFOR
X4 PHARMACEUTICALS INC
$400.55M99,146,7430.10%7.96%Net SellingNet Selling
ELOX
ELOXX PHARMACEUTICALS INC
$60.55M4,036,4590.00%100.00%Net Buying
MGNX
MACROGENICS INC
$280.28M63,700,1870.08%37.81%Net SellingNet Buying
NBTX
NANOBIOTIX SA
$1.88B48,410,0680.01%0.00%
CCCC
C4 THERAPEUTICS INC
$462.57M123,025,1360.10%16.27%Net SellingNet Selling
NAGE
NIAGEN BIOSCIENCE INC
$250.83M79,126,0020.02%99.98%Net BuyingNet Buying
LGND
LIGAND PHARMACEUTICALS INC
$5.69B19,935,6090.02%99.98%Net SellingNet Selling
XNCR
XENCOR INC
$1.98B74,353,3970.11%42.93%Net SellingNet Selling
UTHR
UNITED THERAPEUTICS CORP
$20.91B42,890,6920.10%14.82%Net SellingNet Selling
OKUR
ONKURE THERAPEUTICS INC
$144.98M40,496,3090.09%72.59%Net SellingNet Selling
STTK
SHATTUCK LABS INC
$681.47M100,363,2530.08%15.04%Net BuyingNet Buying
ALGS
ALIGOS THERAPEUTICS INC
$77.56M12,489,1160.01%99.99%
AUTL
AUTOLUS THERAPEUTICS PLC
$596.20M266,162,5400.05%0.54%Net BuyingNet Buying
RANI
RANI THERAPEUTICS HOLDINGS INC
$120.58M139,395,3190.03%45.58%Net SellingNet Buying
ATRA
ATARA BIOTHERAPEUTICS INC
$97.97M10,037,7100.03%99.97%Net BuyingNet Buying
SRPT
SAREPTA THERAPEUTICS INC
$2.38B105,627,0210.10%29.44%Net Selling
SRZN
SURROZEN INC
$267.51M11,753,5580.06%99.94%Net BuyingNet Selling
AXSM
AXSOME THERAPEUTICS INC
$10.83B52,380,8180.07%58.03%Net SellingNet Selling
KZIA
KAZIA THERAPEUTICS LTD
$697.73M5,667,995,7340.00%0.39%
EDIT
EDITAS MEDICINE INC
$496.06M153,580,0350.08%21.44%Net SellingNet Selling
HYPD
HYPERION DEFI INC
$51.28M15,539,4340.01%99.99%Net Buying
ALLO
ALLOGENE THERAPEUTICS INC
$680.62M345,490,8810.09%22.54%Net SellingNet Selling
RNAC
CARTESIAN THERAPEUTICS INC
$280.47M30,255,3520.02%99.98%Net Buying
PRQR
PROQR THERAPEUTICS NV
$222.96M107,710,9160.06%2.28%Net BuyingNet Buying
CRMD
CORMEDIX INC
$657.07M77,944,3240.06%9.76%Net SellingNet Selling
INDP
INDAPTUS THERAPEUTICS INC
$162.56M133,242,3240.00%74.86%Net Buying

Biotech Stocks FAQ

What are the best biotech stocks to buy right now in Sep 2026?

According to Zen Ratings, our proprietary rating system that evaluates 115 factors proven to drive growth in stocks and assigns each stock in our system an overall letter grade as well as 7 individual Component Grades for Value, Growth, Momentum, Sentiment, Safety, Financials, and proprietary AI algorithms, the 3 best biotechnology stocks to buy right now are:

1. Puma Biotechnology (NASDAQ:PBYI)


Puma Biotechnology (NASDAQ:PBYI) is the #1 top biotech stock out of 607 with a Zen Rating of A. Stocks with a rating of A have had an average return of +28.5% per year. Learn more.

The Component Grade breakdown for Puma Biotechnology (NASDAQ:PBYI) is: Value: A, Growth: C, Momentum: A, Sentiment: B, Safety: C, Financials: A, and AI: C.

Puma Biotechnology (NASDAQ:PBYI) has a Due Diligence Score of 48, which is 24 points higher than the biotech industry average of 24.

PBYI passed 15 out of 33 due diligence checks and has strong fundamentals. Puma Biotechnology has seen its stock return 86.89% over the past year, overperforming other biotech stocks by 99 percentage points.

Puma Biotechnology has an average 1 year price target of $6.00, a downside of -37.17% from Puma Biotechnology's current stock price of $9.55.

Puma Biotechnology stock has a consensus Hold recommendation according to Wall Street analysts. Of the 1 analyst covering Puma Biotechnology, 0% have issued a Strong Buy rating, 0% have issued a Buy, 100% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

2. Corcept Therapeutics (NASDAQ:CORT)


Corcept Therapeutics (NASDAQ:CORT) is the #2 top biotech stock out of 607 with a Zen Rating of A. Stocks with a rating of A have had an average return of +28.5% per year. Learn more.

The Component Grade breakdown for Corcept Therapeutics (NASDAQ:CORT) is: Value: B, Growth: A, Momentum: B, Sentiment: A, Safety: C, Financials: B, and AI: C.

Corcept Therapeutics (NASDAQ:CORT) has a Due Diligence Score of 50, which is 26 points higher than the biotech industry average of 24.

CORT passed 17 out of 33 due diligence checks and has strong fundamentals. Corcept Therapeutics has seen its stock return 60.91% over the past year, overperforming other biotech stocks by 73 percentage points.

Corcept Therapeutics has an average 1 year price target of $122.60, an upside of 9.84% from Corcept Therapeutics's current stock price of $111.62.

Corcept Therapeutics stock has a consensus Buy recommendation according to Wall Street analysts. Of the 5 analysts covering Corcept Therapeutics, 60% have issued a Strong Buy rating, 20% have issued a Buy, 0% have issued a hold, while 20% have issued a Sell rating, and 0% have issued a Strong Sell.

3. Precigen (NASDAQ:PGEN)


Precigen (NASDAQ:PGEN) is the #3 top biotech stock out of 607 with a Zen Rating of A. Stocks with a rating of A have had an average return of +28.5% per year. Learn more.

The Component Grade breakdown for Precigen (NASDAQ:PGEN) is: Value: C, Growth: A, Momentum: B, Sentiment: B, Safety: D, Financials: C, and AI: B.

Precigen (NASDAQ:PGEN) has a Due Diligence Score of 29, which is 5 points higher than the biotech industry average of 24.

PGEN passed 10 out of 33 due diligence checks and has average fundamentals. Precigen has seen its stock return 55.7% over the past year, overperforming other biotech stocks by 67 percentage points.

Precigen has an average 1 year price target of $14.50, an upside of 104.23% from Precigen's current stock price of $7.10.

Precigen stock has a consensus Buy recommendation according to Wall Street analysts. Of the 2 analysts covering Precigen, 0% have issued a Strong Buy rating, 100% have issued a Buy, 0% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

What are the biotech stocks with highest dividends?

Out of 6 biotech stocks that have issued dividends in the past year, the 3 biotech stocks with the highest dividend yields are:

1. Oramed Pharmaceuticals (NASDAQ:ORMP)


Oramed Pharmaceuticals (NASDAQ:ORMP) has an annual dividend yield of 4.99%, which is 3 percentage points higher than the biotech industry average of 1.81%.

Oramed Pharmaceuticals's dividend payout ratio of 5.9% indicates that its high dividend yield is sustainable for the long-term.

2. Novo Nordisk (Ozempic) (NYSE:NVO)


Novo Nordisk (Ozempic) (NYSE:NVO) has an annual dividend yield of 3.98%, which is 2 percentage points higher than the biotech industry average of 1.81%. Novo Nordisk (Ozempic)'s dividend payout is not stable, having dropped more than 10% ten times in the last 10 years. Novo Nordisk (Ozempic)'s dividend has shown consistent growth over the last 10 years.

Novo Nordisk (Ozempic)'s dividend payout ratio of 46.1% indicates that its dividend yield is sustainable for the long-term.

3. Royalty Pharma (NASDAQ:RPRX)


Royalty Pharma (NASDAQ:RPRX) has an annual dividend yield of 1.45%, which is the same as the biotech industry average of 1.81%. Royalty Pharma's dividend payout is stable, having never dropped by more than 10% in the last 10 years. Royalty Pharma's dividend has shown consistent growth over the last 10 years.

Royalty Pharma's dividend payout ratio of 48.4% indicates that its dividend yield is sustainable for the long-term.

Why are biotech stocks down?

Biotech stocks were down -0.32% in the last day, and up 1.53% over the last week. Clearmind Medicine was the among the top losers in the biotechnology industry, dropping -31.76% yesterday.

Clearmind shares are trading lower. The company announced a definitive agreement to acquire a 51% controlling stake in Charging Robotics for an aggregate purchase price of $2.5 million.

What are the most undervalued biotech stocks?

Based on the Valuation rating, one of the 7 components of a stocks overall Zen Ratings grade, which evaluates factors including estimated earnings yield, earnings before interest and taxes/enterprise value, cash flow yield, free cash flow to price, and price-to-earnings growth (PEG ratio), the 3 most undervalued biotech stocks right now are:

1. Harmony Biosciences Holdings (NASDAQ:HRMY)


Harmony Biosciences Holdings (NASDAQ:HRMY) is the most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Harmony Biosciences Holdings has a valuation score of 43, which is 30 points higher than the biotech industry average of 13. It passed 3 out of 7 valuation due diligence checks.

Harmony Biosciences Holdings's stock has gained 16.39% in the past year. It has overperformed other stocks in the biotech industry by 28 percentage points.

2. Jazz Pharmaceuticals (NASDAQ:JAZZ)


Jazz Pharmaceuticals (NASDAQ:JAZZ) is the second most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Jazz Pharmaceuticals has a valuation score of 71, which is 58 points higher than the biotech industry average of 13. It passed 5 out of 7 valuation due diligence checks.

Jazz Pharmaceuticals's stock has gained 92.79% in the past year. It has overperformed other stocks in the biotech industry by 104 percentage points.

3. Exelixis (NASDAQ:EXEL)


Exelixis (NASDAQ:EXEL) is the third most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Exelixis has a valuation score of 14, which is 1 points higher than the biotech industry average of 13. It passed 1 out of 7 valuation due diligence checks.

Exelixis's stock has gained 57.87% in the past year. It has overperformed other stocks in the biotech industry by 70 percentage points.

Are biotech stocks a good buy now?

67.51% of biotech stocks rated by analysts are a strong buy right now. On average, analysts expect biotech stocks to rise by 49.12% over the next year.

2.88% of biotech stocks have a Zen Rating of A (Strong Buy), 3.98% of biotech stocks are rated B (Buy), 42.48% are rated C (Hold), 39.6% are rated D (Sell), and 11.06% are rated F (Strong Sell).

What is the average p/e ratio of the biotechnology industry?

The average P/E ratio of the biotechnology industry is 10.49x.
WallStreetZen does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.

Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.