| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Michael S. Perry | Director | 2026-08-18 | 11,600 | $87.30 | $1.01MSell |
| Adeoye Y. Olukotun | Director | 2026-08-18 | 2,000 | $86.96 | $173.92kSell |
| Hongbo Lu | Director | 2026-05-12 | 2,970 | $76.88 | $228.33kSell |
| James C. Hamilton | Chief Medical Officer | 2026-04-23 | 10,000 | $75.00 | $750.00kSell |
| Daniel Joseph Apel | Chief Financial Officer | 2026-04-22 | 1,157 | $70.45 | $81.51kSell |
| Daniel Joseph Apel | Chief Financial Officer | 2026-04-22 | 3,208 | $70.11 | $224.91kSell |
| Daniel Joseph Apel | Chief Financial Officer | 2026-04-22 | 8,730 | $71.92 | $627.86kSell |
| James C. Hamilton | Chief Medical Officer | 2026-03-05 | 10,000 | $64.19 | $641.90kSell |
| Patrick 1. Obrien | COO | 2026-01-05 | 600 | $61.12 | $36.67kSell |
| James C. Hamilton | Chief Medical Officer | 2026-01-05 | 4,625 | $61.24 | $283.24kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| David M. Knott | 3.97% | 5,609,690 | $369.79M | Insider |
| Christopher Richard Anzalone | 2.69% | 3,792,739 | $250.02M | Insider |
| Bruce D. Given | 0.60% | 850,730 | $56.08M | Insider |
| Patrick 1. Obrien | 0.39% | 547,408 | $36.09M | Insider |
| R. Bruce Stewart | 0.36% | 511,500 | $33.72M | Insider |
| Kenneth Allen Myszkowski | 0.32% | 455,433 | $30.02M | Insider |
| James C. Hamilton | 0.16% | 226,958 | $14.96M | Insider |
| Zhen Li | 0.14% | 201,700 | $13.30M | Insider |
| Martin Javier San | 0.14% | 198,497 | $13.08M | Insider |
| Daniel Joseph Apel | 0.12% | 162,905 | $10.74M | Insider |