| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Pablo J. Cagnoni | President Global Head of RD | 2026-06-01 | 25,469 | $95.59 | $2.43MSell |
| Thomas Tray | Principal Accounting Officer | 2026-05-26 | 2,051 | $97.35 | $199.66kSell |
| Jean Jacques Bienaime | Director | 2026-05-26 | 15,000 | $84.53 | $1.27MBuy |
| Jean Jacques Bienaime | Director | 2026-05-26 | 13,059 | $97.10 | $1.27MSell |
| Paul J. Clancy | Director | 2026-05-19 | 15,000 | $84.53 | $1.27MBuy |
| Paul J. Clancy | Director | 2026-05-19 | 15,000 | $94.93 | $1.42MSell |
| Baker Bros Advisors LP | Director | 2026-05-08 | 15,000 | $84.53 | $1.27MBuy |
| Baker Bros Advisors LP | Director | 2026-05-08 | 15,000 | $84.53 | $1.27MBuy |
| Pablo J. Cagnoni | President Global Head of RD | 2026-04-17 | 12,590 | $71.93 | $905.60kBuy |
| Pablo J. Cagnoni | President Global Head of RD | 2026-04-17 | 18,667 | $96.50 | $1.80MSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Baker Bros Advisors LP | 15.39% | 30,744,412 | $3.11B | Institution |
| Julian Baker | 9.94% | 19,851,744 | $2.01B | Insider |
| Blackrock Inc | 9.50% | 18,978,198 | $1.92B | Institution |
| Baker Brothers Life Sciences LP | 6.23% | 12,445,783 | $1.26B | Insider |
| Baker Brothers Life Sciences Capital GP LLC | 6.22% | 12,430,783 | $1.26B | Insider |
| Dodge Cox | 6.13% | 12,252,356 | $1.24B | Institution |
| Vanguard Capital Management LLC | 5.47% | 10,930,066 | $1.11B | Institution |
| State Street Corp | 4.83% | 9,641,384 | $976.09M | Institution |
| Vanguard Portfolio Management LLC | 3.88% | 7,759,183 | $785.54M | Institution |
| Aqr Capital Management LLC | 2.91% | 5,807,930 | $587.99M | Institution |