| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Paul J. Clancy | Director | 2026-05-19 | 15,000 | $94.93 | $1.42MSell |
| Paul J. Clancy | Director | 2026-05-19 | 15,000 | $84.53 | $1.27MBuy |
| Baker Bros Advisors LP | Director | 2026-05-08 | 15,000 | $84.53 | $1.27MBuy |
| Baker Bros Advisors LP | Director | 2026-05-08 | 15,000 | $84.53 | $1.27MBuy |
| Pablo J. Cagnoni | President Global Head of RD | 2026-04-17 | 6,077 | $64.25 | $390.45kBuy |
| Pablo J. Cagnoni | President Global Head of RD | 2026-04-17 | 18,667 | $96.50 | $1.80MSell |
| Pablo J. Cagnoni | President Global Head of RD | 2026-04-17 | 12,590 | $71.93 | $905.60kBuy |
| Paul J. Clancy | Director | 2026-03-31 | 265 | $94.12 | $24.94kBuy |
| Edmund Harrigan | Director | 2026-03-31 | 269 | $94.12 | $25.32kBuy |
| Matteo Trotta | EVP GM Dermatology US | 2026-03-25 | 537 | $92.23 | $49.53kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Baker Bros Advisors LP | 15.39% | 30,744,412 | $2.99B | Institution |
| Julian Baker | 9.94% | 19,851,744 | $1.93B | Insider |
| Blackrock Inc | 9.50% | 18,978,198 | $1.85B | Institution |
| Baker Brothers Life Sciences LP | 6.23% | 12,445,783 | $1.21B | Insider |
| Baker Brothers Life Sciences Capital GP LLC | 6.22% | 12,430,783 | $1.21B | Insider |
| Dodge Cox | 6.13% | 12,252,356 | $1.19B | Institution |
| Vanguard Capital Management LLC | 5.47% | 10,930,066 | $1.06B | Institution |
| State Street Corp | 4.83% | 9,641,384 | $939.17M | Institution |
| Vanguard Portfolio Management LLC | 3.88% | 7,759,183 | $755.82M | Institution |
| Aqr Capital Management LLC | 2.91% | 5,807,930 | $565.75M | Institution |