| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Mohamed Khairie Issa | EVP;Head | 2026-07-16 | 1,093 | $115.01 | $125.71kSell |
| Steven H. Stein | CMO;Head | 2026-07-16 | 1,877 | $114.73 | $215.35kSell |
| Steven H. Stein | CMO;Head | 2026-07-15 | 3,088 | $115.09 | $355.40kSell |
| Patrick A. Mayes | CSci;EVP | 2026-07-15 | 1,512 | $115.09 | $174.02kSell |
| Pablo J. Cagnoni | Pres;Head | 2026-07-15 | 4,950 | $115.09 | $569.70kSell |
| Thomas Tray | PAO | 2026-07-15 | 1,098 | $115.09 | $126.37kSell |
| Mohamed Khairie Issa | EVP;Head | 2026-07-15 | 1,099 | $115.09 | $126.48kSell |
| Steven H. Stein | CMO;Head | 2026-07-15 | 28,237 | $113.05 | $3.19MSell |
| Thomas Tray | PAO | 2026-07-14 | 692 | $114.88 | $79.50kSell |
| Patrick A. Mayes | CSci;EVP | 2026-07-14 | 437 | $114.88 | $50.20kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Baker Bros Advisors LP | 15.17% | 30,744,412 | $3.64B | Institution |
| Julian Baker | 9.79% | 19,851,744 | $2.35B | Insider |
| Blackrock Inc | 9.36% | 18,978,198 | $2.25B | Institution |
| Baker Brothers Life Sciences LP | 6.14% | 12,445,783 | $1.47B | Insider |
| Baker Brothers Life Sciences Capital GP LLC | 6.13% | 12,430,783 | $1.47B | Insider |
| Dodge Cox | 6.04% | 12,252,356 | $1.45B | Institution |
| Vanguard Capital Management LLC | 5.39% | 10,930,066 | $1.29B | Institution |
| State Street Corp | 4.76% | 9,641,384 | $1.14B | Institution |
| Vanguard Portfolio Management LLC | 3.83% | 7,759,183 | $918.92M | Institution |
| Aqr Capital Management LLC | 2.87% | 5,807,930 | $687.83M | Institution |