| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Orbis Allan Gray Ltd | 20.12% | 12,925,578 | $343.04M | Institution |
| Alliancebernstein LP | 14.88% | 9,557,149 | $253.65M | Institution |
| Paradigm Biocapital Advisors LP | 12.40% | 7,967,836 | $211.47M | Institution |
| Arrowstreet Capital Limited Partnership | 7.74% | 4,975,324 | $132.05M | Institution |
| Blackrock Inc | 7.06% | 4,536,565 | $120.40M | Institution |
| Renaissance Technologies LLC | 6.87% | 4,414,550 | $117.16M | Institution |
| Deep Track Capital LP | 5.70% | 3,663,250 | $97.22M | Institution |
| Harding Loevner LP | 5.03% | 3,231,601 | $85.77M | Institution |
| Deerfield Management Company LP | 3.83% | 2,462,000 | $65.34M | Institution |
| First Trust Advisors LP | 3.83% | 2,461,342 | $65.32M | Institution |