| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Orbis Allan Gray Ltd | 22.45% | 14,418,462 | $372.28M | Institution |
| Alliancebernstein LP | 16.93% | 10,877,094 | $280.85M | Institution |
| Paradigm Biocapital Advisors LP | 10.96% | 7,039,834 | $181.77M | Institution |
| Arrowstreet Capital Limited Partnership | 7.75% | 4,978,058 | $128.53M | Institution |
| Blackrock Inc | 7.15% | 4,593,901 | $118.61M | Institution |
| Renaissance Technologies LLC | 5.44% | 3,492,850 | $90.19M | Institution |
| Harding Loevner LP | 5.25% | 3,370,143 | $87.02M | Institution |
| Morgan Stanley | 2.86% | 1,834,439 | $47.37M | Institution |
| First Trust Advisors LP | 2.08% | 1,335,273 | $34.48M | Institution |
| Goldman Sachs Group Inc 1 | 2.08% | 1,333,303 | $34.43M | Institution |