| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| William Lewis | Chair and CEO | 2026-06-25 | 1,292 | $106.27 | $137.30kSell |
| William Lewis | Chair and CEO | 2026-06-25 | 12,518 | $30.46 | $381.30kBuy |
| William Lewis | Chair and CEO | 2026-06-25 | 8,880 | $17.16 | $152.38kBuy |
| William Lewis | Chair and CEO | 2026-06-25 | 12,091 | $102.34 | $1.24MSell |
| William Lewis | Chair and CEO | 2026-06-25 | 1,836 | $103.10 | $189.29kSell |
| William Lewis | Chair and CEO | 2026-06-25 | 3,723 | $104.28 | $388.23kSell |
| William Lewis | Chair and CEO | 2026-06-25 | 2,456 | $105.27 | $258.54kSell |
| Michael Alexander Smith | Chief Legal Officer | 2026-06-22 | 1,806 | $95.82 | $173.05kSell |
| William Lewis | Chair and CEO | 2026-06-08 | 6,515 | $94.03 | $612.61kSell |
| Martina Md Flammer | Chief Medical Officer | 2026-06-05 | 1,858 | $103.78 | $192.82kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Jpmorgan Chase Co | 11.14% | 24,150,499 | $2.70B | Institution |
| Richard S. Kollender | 10.12% | 21,924,540 | $2.45B | Insider |
| Darwin Global Management Ltd | 7.75% | 16,805,184 | $1.88B | Institution |
| Blackrock Inc | 7.69% | 16,678,146 | $1.86B | Institution |
| Fmr LLC | 6.07% | 13,160,167 | $1.47B | Institution |
| Vanguard Portfolio Management LLC | 4.79% | 10,371,802 | $1.16B | Institution |
| Vanguard Capital Management LLC | 4.45% | 9,642,131 | $1.08B | Institution |
| Baker Bros Advisors LP | 3.42% | 7,421,111 | $828.20M | Institution |
| Artisan Partners Limited Partnership | 3.01% | 6,527,301 | $728.45M | Institution |
| D E Shaw Co Inc | 2.60% | 5,625,825 | $627.84M | Institution |