| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Anthony Mancini | Chief Global Commercialization Officer | 2026-04-27 | 1,049 | $132.88 | $139.39kSell |
| Anthony Mancini | Chief Global Commercialization Officer | 2026-04-27 | 1,671 | $131.66 | $220.01kSell |
| Anthony Mancini | Chief Global Commercialization Officer | 2026-04-27 | 3,120 | $33.62 | $104.89kBuy |
| Anthony Mancini | Chief Global Commercialization Officer | 2026-04-27 | 400 | $134.34 | $53.73kSell |
| Mark A. Goldsmith | President and Chief Executive Officer | 2026-04-15 | 120,000 | $150.09 | $18.01MSell |
| Mark A. Goldsmith | President and Chief Executive Officer | 2026-04-15 | 23,244 | $4.09 | $95.07kBuy |
| Mark A. Goldsmith | President and Chief Executive Officer | 2026-04-15 | 96,756 | $4.73 | $457.66kBuy |
| Anthony Mancini | Chief Global Commercialization Officer | 2026-03-25 | 400 | $97.21 | $38.88kSell |
| Anthony Mancini | Chief Global Commercialization Officer | 2026-03-25 | 11,036 | $96.43 | $1.06MSell |
| Anthony Mancini | Chief Global Commercialization Officer | 2026-03-25 | 21,086 | $95.49 | $2.01MSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Farallon Capital Management LLC | 6.40% | 13,604,796 | $1.98B | Institution |
| Blackrock Inc | 5.27% | 11,212,706 | $1.63B | Institution |
| Janus Henderson Group PLC | 4.59% | 9,766,496 | $1.42B | Institution |
| Baker Bros Advisors LP | 4.49% | 9,555,357 | $1.39B | Institution |
| Fmr LLC | 3.98% | 8,464,314 | $1.23B | Institution |
| Vanguard Capital Management LLC | 3.93% | 8,362,284 | $1.22B | Institution |
| Thilo Schroeder | 3.80% | 8,085,752 | $1.18B | Insider |
| Nextech Invest Ltd | 3.58% | 7,601,087 | $1.11B | Institution |
| Vanguard Portfolio Management LLC | 3.53% | 7,502,623 | $1.09B | Institution |
| Paradigm Biocapital Advisors LP | 3.13% | 6,655,703 | $969.47M | Institution |