| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Stephen L. Sabba | Director | 2026-06-16 | 2,145 | $254.00 | $544.83kSell |
| Stephen L. Sabba | Director | 2026-06-16 | 2,145 | $66.13 | $141.85kBuy |
| Jason Haas | Director | 2026-06-12 | 3,461 | $256.08 | $886.29kSell |
| Jason Haas | Director | 2026-06-12 | 1,000 | $51.56 | $51.56kBuy |
| Jason Haas | Director | 2026-06-12 | 3,000 | $51.56 | $154.68kBuy |
| Jason Haas | Director | 2026-06-12 | 3,000 | $255.01 | $765.03kSell |
| Jason Aryeh | Director | 2026-06-11 | 4,500 | $250.00 | $1.13MSell |
| John L. Lamattina | Director | 2026-06-10 | 232 | $248.11 | $57.56kSell |
| Jason Aryeh | Director | 2026-06-10 | 500 | $250.00 | $125.00kSell |
| John L. Lamattina | Director | 2026-06-10 | 3,405 | $251.62 | $856.75kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Bvf Partners L P | 316.02% | 63,334,719 | $16.60B | Insider |
| David M. Knott | 62.93% | 12,611,277 | $3.31B | Insider |
| Daniel S. Loeb | 48.67% | 9,754,756 | $2.56B | Insider |
| Investment 10 LLC | 17.87% | 3,582,065 | $939.11M | Insider |
| Blackrock Inc | 14.78% | 2,961,923 | $776.53M | Institution |
| Vanguard Portfolio Management LLC | 5.49% | 1,100,267 | $288.46M | Institution |
| Janus Henderson Group PLC | 5.04% | 1,009,891 | $264.76M | Institution |
| Vanguard Capital Management LLC | 4.23% | 848,089 | $222.34M | Institution |
| Invesco Ltd | 4.11% | 823,604 | $215.92M | Institution |
| State Street Corp | 3.89% | 778,856 | $204.19M | Institution |