| Name | Role | Date | Shares | Price | Value | 
|---|---|---|---|---|---|
| Amy E. McKee | Director | 2025-08-29 | 676 | $8.31 | $5.62kBuy | 
| Vincent Milano | Director | 2025-08-29 | 676 | $8.31 | $5.62kBuy | 
| Steven Frank | Director | 2025-08-29 | 1,353 | $8.31 | $11.24kBuy | 
| Theresa Heggie | Director | 2025-08-13 | 40,000 | $5.41 | $216.40kBuy | 
| Theresa Heggie | Director | 2025-08-13 | 70,000 | $8.51 | $595.84kSell | 
| Theresa Heggie | Director | 2025-08-13 | 30,000 | $2.91 | $87.30kBuy | 
| Steven Frank | Director | 2025-05-30 | 333 | $10.75 | $3.58kBuy | 
| Vincent Milano | Director | 2025-05-30 | 523 | $10.75 | $5.62kBuy | 
| Helen M. Thackray | Chief RD Officer | 2025-03-31 | 7,525 | $7.50 | $56.44kSell | 
| Vincent Milano | Director | 2025-02-28 | 653 | $8.61 | $5.62kBuy | 
| Name | Hold | Shares | Value | Type | 
|---|---|---|---|---|
| Baker Bros Advisors LP | 10.26% | 21,543,334 | $157.48M | Insider | 
| Blackrock Inc | 10.21% | 21,425,849 | $156.62M | Institution | 
| Vanguard Group Inc | 9.79% | 20,544,248 | $150.18M | Institution | 
| State Street Corp | 4.05% | 8,505,392 | $62.17M | Institution | 
| Kynam Capital Management LP | 4.03% | 8,463,742 | $61.87M | Institution | 
| Alkeon Capital Management LLC | 2.72% | 5,714,021 | $41.77M | Institution | 
| Ubs Group Ag | 2.67% | 5,614,651 | $41.04M | Institution | 
| Morgan Stanley | 2.54% | 5,329,679 | $38.96M | Institution | 
| Geode Capital Management LLC | 2.41% | 5,054,610 | $36.95M | Institution | 
| Deerfield Management Company LP | 2.24% | 4,692,000 | $34.30M | Institution |