| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Kathleen Goin | Chief Operating Officer | 2026-03-18 | 304 | $119.08 | $36.20kSell |
| Kathleen Goin | Chief Operating Officer | 2026-03-18 | 2,268 | $117.56 | $266.63kSell |
| Kathleen Goin | Chief Operating Officer | 2026-03-18 | 2,148 | $9.08 | $19.50kBuy |
| Kathleen Goin | Chief Operating Officer | 2026-03-18 | 2,154 | $7.14 | $15.38kBuy |
| Kathleen Goin | Chief Operating Officer | 2026-03-18 | 1,730 | $118.37 | $204.78kSell |
| George M. Jenkins | Director | 2026-02-27 | 4,000 | $125.00 | $500.00kBuy |
| Elaine J. Heron | Director | 2026-02-27 | 2,400 | $125.00 | $300.00kBuy |
| Kathleen Goin | Chief Operating Officer | 2026-02-18 | 2,148 | $9.08 | $19.50kBuy |
| Kathleen Goin | Chief Operating Officer | 2026-02-18 | 2,154 | $7.14 | $15.38kBuy |
| Kathleen Goin | Chief Operating Officer | 2026-02-18 | 3,026 | $79.16 | $239.53kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Aquilo Capital Management LLC | 31.05% | 3,675,530 | $406.73M | Insider |
| Wes Kaupinen | 13.58% | 1,607,228 | $177.86M | Insider |
| Suvretta Capital Management LLC | 7.54% | 892,400 | $98.75M | Institution |
| Bvf Inc | 7.43% | 879,009 | $97.27M | Institution |
| Frazier Life Sciences Management LP | 6.10% | 722,400 | $79.94M | Institution |
| First Light Asset Management LLC | 5.99% | 709,141 | $78.47M | Institution |
| Vanguard Group Inc | 4.74% | 560,616 | $62.04M | Institution |
| Blackrock Inc | 4.72% | 559,065 | $61.87M | Institution |
| State Street Corp | 3.55% | 420,462 | $46.53M | Institution |
| Summit Partners Public Asset Management LLC | 3.29% | 389,420 | $43.09M | Institution |