| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Owen Hughes | Chief Executive Officer | 2025-12-04 | 100,000 | $25.05 | $2.51MBuy |
| Thomas M. Burns | SVP Finance CFO | 2025-09-22 | 4,300 | $35.98 | $154.71kSell |
| Thomas M. Burns | SVP Finance CFO | 2025-09-22 | 15 | $36.93 | $553.95Sell |
| Thomas M. Burns | SVP Finance CFO | 2025-09-22 | 15 | $36.81 | $552.15Sell |
| Bradley Sitko | Chief Investment Officer | 2025-06-30 | 2,000 | $25.39 | $50.78kBuy |
| Owen Hughes | Chief Executive Officer | 2025-05-20 | 25,637 | $25.38 | $650.67kSell |
| Thomas M. Burns | SVP Finance CFO | 2025-05-20 | 10,482 | $25.38 | $266.03kSell |
| Bvf Partners L P | 10% Owner | 2025-05-16 | 127,407 | $27.10 | $3.45MSell |
| Bvf Partners L P | 10% Owner | 2025-05-16 | 265,316 | $27.10 | $7.19MSell |
| Joseph M. Limber | Director | 2025-04-07 | 5,243 | $25.60 | $134.22kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Baker Brothers Life Sciences Capital GP LLC | 114.28% | 13,606,093 | $405.05M | Insider |
| Baker Brothers Life Sciences LP | 114.28% | 13,606,093 | $405.05M | Insider |
| Bvf Inc | 21.76% | 2,590,303 | $77.11M | Institution |
| Morgan Stanley | 14.40% | 1,714,668 | $51.05M | Institution |
| 667 LP | 13.32% | 1,585,591 | $47.20M | Insider |
| Baker Biotech Capital GP LLC | 13.32% | 1,585,591 | $47.20M | Insider |
| Bvf Partners L P | 10.65% | 1,267,545 | $37.73M | Insider |
| Fmr LLC | 9.76% | 1,161,889 | $34.59M | Institution |
| Bvf GP Holdings LLC | 9.27% | 1,103,314 | $32.85M | Insider |
| Vanguard Group Inc | 5.89% | 701,657 | $20.89M | Institution |