| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Owen Hughes | Chief Executive Officer | 2025-12-04 | 100,000 | $25.05 | $2.51MBuy |
| Thomas M. Burns | SVP Finance CFO | 2025-09-22 | 4,300 | $35.98 | $154.71kSell |
| Thomas M. Burns | SVP Finance CFO | 2025-09-22 | 15 | $36.93 | $553.95Sell |
| Thomas M. Burns | SVP Finance CFO | 2025-09-22 | 15 | $36.81 | $552.15Sell |
| Bradley Sitko | Chief Investment Officer | 2025-06-30 | 2,000 | $25.39 | $50.78kBuy |
| Thomas M. Burns | SVP Finance CFO | 2025-05-20 | 10,482 | $25.38 | $266.03kSell |
| Owen Hughes | Chief Executive Officer | 2025-05-20 | 25,637 | $25.38 | $650.67kSell |
| Bvf Partners L P | 10% Owner | 2025-05-16 | 127,407 | $27.10 | $3.45MSell |
| Bvf Partners L P | 10% Owner | 2025-05-16 | 265,316 | $27.10 | $7.19MSell |
| Joseph M. Limber | Director | 2025-04-07 | 5,243 | $25.60 | $134.22kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Baker Brothers Life Sciences Capital GP LLC | 109.88% | 13,606,093 | $414.85M | Insider |
| Baker Brothers Life Sciences LP | 109.88% | 13,606,093 | $414.85M | Insider |
| Bvf Inc | 20.92% | 2,590,303 | $78.98M | Institution |
| Morgan Stanley | 13.30% | 1,646,996 | $50.22M | Institution |
| 667 LP | 12.80% | 1,585,591 | $48.34M | Insider |
| Baker Biotech Capital GP LLC | 12.80% | 1,585,591 | $48.34M | Insider |
| Bvf Partners L P | 10.24% | 1,267,545 | $38.65M | Insider |
| Bvf GP Holdings LLC | 8.91% | 1,103,314 | $33.64M | Insider |
| Fmr LLC | 8.68% | 1,074,325 | $32.76M | Institution |
| Vanguard Group Inc | 5.40% | 668,111 | $20.37M | Institution |