| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Stephen Stout | General Counsel Corporate Secretary and Chief Ethics and Compliance Officer | 2026-01-25 | 593 | $4.15 | $2.46kSell |
| Arundathy N. Pandite | Chief Medical Officer | 2026-01-25 | 3,195 | $4.15 | $13.26kSell |
| Andrew R. Neill | Chief Financial Officer | 2026-01-25 | 2,589 | $4.15 | $10.74kSell |
| Casi Deyoung | Chief Business Officer | 2026-01-25 | 2,286 | $4.15 | $9.49kSell |
| Arundathy N. Pandite | Chief Medical Officer | 2026-01-10 | 6,851 | $4.75 | $32.54kSell |
| Casi Deyoung | Chief Business Officer | 2026-01-10 | 5,699 | $4.75 | $27.07kSell |
| Andrew R. Neill | Chief Financial Officer | 2026-01-10 | 6,660 | $4.75 | $31.64kSell |
| Stephen Stout | General Counsel Corporate Secretary and Chief Ethics and Compliance Officer | 2026-01-10 | 4,153 | $4.75 | $19.73kSell |
| Stephen Stout | General Counsel Corporate Secretary and Chief Ethics and Compliance Officer | 2025-08-25 | 12,805 | $0.87 | $11.11kBuy |
| Orbimed Advisors LLC | Director | 2025-08-25 | 1,051,021 | $0.87 | $912.29kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Adage Capital Partners GP LLC | 9.97% | 6,306,127 | $25.35M | Institution |
| Orbimed Advisors LLC | 9.97% | 6,306,127 | $25.35M | Institution |
| Redmile Group LLC | 8.75% | 5,539,724 | $22.27M | Institution |
| Redmile Group LLC | 8.75% | 5,539,724 | $22.27M | Insider |
| Prosight Management LP | 8.61% | 5,451,195 | $21.91M | Institution |
| Josiah Hornblower | 5.24% | 3,313,796 | $13.32M | Insider |
| Taylor Schreiber | 4.28% | 2,707,362 | $10.88M | Insider |
| Vanguard Group Inc | 3.36% | 2,128,401 | $8.56M | Institution |
| 683 Capital Management LLC | 2.42% | 1,532,216 | $6.16M | Institution |
| Clark Estates Inc | 2.33% | 1,475,648 | $5.93M | Institution |