| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| John Charles Thomas | EVP General Counsel | 2026-06-25 | 1,000 | $179.25 | $179.25kBuy |
| John Charles Thomas | EVP General Counsel | 2026-06-25 | 1,000 | $347.27 | $347.27kSell |
| Krish S. Krishnan | President and CEO | 2026-06-04 | 640 | $302.24 | $193.43kSell |
| Krish S. Krishnan | President and CEO | 2026-06-04 | 320 | $300.75 | $96.24kSell |
| Suma Krishnan | President RD | 2026-06-04 | 240 | $311.65 | $74.80kSell |
| Suma Krishnan | President RD | 2026-06-04 | 2,039 | $310.94 | $634.00kSell |
| Suma Krishnan | President RD | 2026-06-04 | 2,801 | $309.95 | $868.16kSell |
| Suma Krishnan | President RD | 2026-06-04 | 3,803 | $308.89 | $1.17MSell |
| Suma Krishnan | President RD | 2026-06-04 | 12,729 | $307.81 | $3.92MSell |
| Suma Krishnan | President RD | 2026-06-04 | 1,348 | $307.10 | $413.96kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Fmr LLC | 14.78% | 4,373,987 | $1.42B | Institution |
| Blackrock Inc | 13.31% | 3,940,456 | $1.28B | Institution |
| Krish S. Krishnan | 10.84% | 3,208,408 | $1.05B | Insider |
| Suma Krishnan | 10.84% | 3,208,408 | $1.05B | Insider |
| Avoro Capital Advisors LLC | 9.76% | 2,888,888 | $941.14M | Institution |
| Vanguard Portfolio Management LLC | 4.92% | 1,456,727 | $474.57M | Institution |
| State Street Corp | 4.44% | 1,314,434 | $428.22M | Institution |
| Vanguard Capital Management LLC | 3.94% | 1,165,324 | $379.64M | Institution |
| Soleus Capital Management LP | 3.90% | 1,153,087 | $375.65M | Institution |
| Capital World Investors | 2.79% | 824,720 | $268.68M | Institution |