WallStreetZenWallStreetZen

NASDAQ: SYRE
Spyre Therapeutics Inc Stock Ownership - Who owns Spyre Therapeutics?

OverviewForecastEarningsRevenueDividendOwnership

Insider buying vs selling

Have Spyre Therapeutics Inc insiders been buying or selling?

Buy
Sell
NameRoleDateSharesPriceValue
Fairmount Funds Management LLCDirector2026-06-234,684,781$85.31
$399.66MSell
Michael Thomas HendersonDirector2026-06-2220,000$100.00
$2.00MSell
Sheldon SloanChief Medical Officer2026-06-038,333$27.46
$228.82kBuy
Sheldon SloanChief Medical Officer2026-06-038,333$75.00
$624.98kSell
Scott L. BurrowsChief Financial Officer2026-06-013,100$72.06
$223.39kSell
Scott L. BurrowsChief Financial Officer2026-06-017,500$14.50
$108.75kBuy
Scott L. BurrowsChief Financial Officer2026-06-012,599$70.77
$183.93kSell
Scott L. BurrowsChief Financial Officer2026-06-011,801$69.75
$125.62kSell
Cameron TurtleChief Executive Officer2026-06-013,294$71.38
$235.13kSell
Cameron TurtleChief Executive Officer2026-06-018,149$70.50
$574.50kSell

1 of 6

SYRE insiders have sold more... subscribe to Premium to read more.
Net Insider Buy/Sell (L12M) Ownership

Be the first to know when SYRE insiders and whales buy or sell their stock.

SYRE Shareholders

What type of owners hold Spyre Therapeutics Inc stock?

Institutional
Insider
Retail
NameHoldSharesValueType
Fmr LLC13.57%11,781,024$1.04BInstitution
Fairmount Funds Management LLC11.84%10,283,659$911.85MInsider
Blackrock Inc6.36%5,521,221$489.57MInstitution
Rtw Investments LP4.80%4,171,996$369.93MInstitution
Fairmount Funds Management LLC4.63%4,018,101$356.29MInstitution
Perceptive Advisors LLC4.36%3,783,225$335.46MInstitution
Venrock Adviser LLC4.24%3,685,448$326.79MInstitution
Baker Bros Advisors LP3.56%3,094,590$274.40MInsider
Vanguard Capital Management LLC3.52%3,057,401$271.10MInstitution
Orbimed Advisors LLC3.26%2,829,748$250.91MInsider

1 of 3

SYRE vs Biotech Stocks

TickerInst. %Insider %Net Insider (L12M)Net Insider (L3M)
SYRE79.26%20.74%Net SellingNet Selling
ABVX63.37%0.00%
MIRM56.48%43.52%Net BuyingNet Buying
RYTM88.71%11.29%Net SellingNet Buying
PTGX84.37%15.63%Net SellingNet Selling
View Top Biotech Stocks

Spyre Therapeutics Stock Ownership FAQ

Who owns Spyre Therapeutics?

Spyre Therapeutics (NASDAQ: SYRE) is owned by 95.17% institutional shareholders, 24.90% Spyre Therapeutics insiders, and 0.00% retail investors. Fairmount Funds Management LLC is the largest individual Spyre Therapeutics shareholder, owning 10.28M shares representing 11.84% of the company. Fairmount Funds Management LLC's Spyre Therapeutics shares are currently valued at $903.83M.

If you're new to stock investing, here's how to buy Spyre Therapeutics stock.
©2026 WallStreetZen
Company
AboutNewsBlogStock Investing FAQPlansPrivacy PolicyTerms of ServiceCancellation & RefundsPerformanceHelp GuidesContactTwitterYouTubeNewsletter
Stock Tools
Top Performing AnalystsStock ScreenerStock ForecastTrending StocksStrong Buy StocksHighest Earnings StocksBest Dividend Paying StocksStatisticsStock Market SectorsStock Market IndustriesHow to Buy Stocks Online
Stock Ideas
Buy The DipBiggest Stock Gainers TodayBiggest Stock Losers Today52 Week High Stocks52 Week Low StocksMost Active Stocks TodayMost Undervalued StocksBest Penny Stocks to Buy NowBest Stocks Under $5Best Stocks Under $10
WallStreetZen does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.

Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.