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NASDAQ: SYRE
Spyre Therapeutics Inc Stock Ownership - Who owns Spyre Therapeutics?

OverviewForecastEarningsRevenueDividendOwnership

Insider buying vs selling

Have Spyre Therapeutics Inc insiders been buying or selling?

Buy
Sell
NameRoleDateSharesPriceValue
Michael Thomas HendersonDirector2026-05-082,404$72.57
$174.46kSell
Michael Thomas HendersonDirector2026-05-0819,269$75.35
$1.45MSell
Michael Thomas HendersonDirector2026-05-0824,814$74.76
$1.86MSell
Michael Thomas HendersonDirector2026-05-0833,513$73.72
$2.47MSell
Cameron TurtleChief Executive Officer2026-05-01300$74.96
$22.49kSell
Scott L. BurrowsChief Financial Officer2026-05-0112,500$14.50
$181.25kBuy
Scott L. BurrowsChief Financial Officer2026-05-0112,500$71.37
$892.13kSell
Sheldon SloanChief Medical Officer2026-05-0178,333$27.46
$2.15MBuy
Sheldon SloanChief Medical Officer2026-05-0121,306$69.53
$1.48MSell
Sheldon SloanChief Medical Officer2026-05-0119,656$70.61
$1.39MSell

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Net Insider Buy/Sell (L12M) Ownership

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SYRE Shareholders

What type of owners hold Spyre Therapeutics Inc stock?

Institutional
Insider
Retail
NameHoldSharesValueType
Fairmount Funds Management LLC16.47%14,301,760$1.09BInsider
Fmr LLC13.40%11,638,819$889.55MInstitution
Blackrock Inc6.36%5,522,101$422.05MInstitution
Rtw Investments LP4.80%4,171,996$318.87MInstitution
Vanguard Group Inc4.65%4,035,074$308.40MInstitution
Fairmount Funds Management LLC4.63%4,018,101$307.10MInstitution
Vr Adviser LLC4.24%3,685,448$281.68MInstitution
Capital International Investors4.02%3,492,541$266.93MInstitution
Baker Bros Advisors LP3.56%3,094,590$236.52MInsider
Perceptive Advisors LLC3.53%3,069,225$234.58MInstitution

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SYRE vs Biotech Stocks

TickerInst. %Insider %Net Insider (L12M)Net Insider (L3M)
SYRE75.92%24.08%Net SellingNet Selling
MIRM53.72%46.28%Net BuyingNet Selling
TGTX58.07%41.93%Net Selling
PTGX82.90%17.10%Net SellingNet Selling
CGON85.41%14.59%Net BuyingNet Buying
View Top Biotech Stocks

Spyre Therapeutics Stock Ownership FAQ

Who owns Spyre Therapeutics?

Spyre Therapeutics (NASDAQ: SYRE) is owned by 93.25% institutional shareholders, 29.57% Spyre Therapeutics insiders, and 0.00% retail investors. Fairmount Funds Management LLC is the largest individual Spyre Therapeutics shareholder, owning 14.30M shares representing 16.47% of the company. Fairmount Funds Management LLC's Spyre Therapeutics shares are currently valued at $1.07B.

If you're new to stock investing, here's how to buy Spyre Therapeutics stock.
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