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NASDAQ: SYRE
Spyre Therapeutics Inc Stock Ownership - Who owns Spyre Therapeutics?

OverviewForecastEarningsRevenueDividendOwnership

Insider buying vs selling

Have Spyre Therapeutics Inc insiders been buying or selling?

Buy
Sell
NameRoleDateSharesPriceValue
Michael Thomas HendersonDirector2026-05-082,404$72.57
$174.46kSell
Michael Thomas HendersonDirector2026-05-0819,269$75.35
$1.45MSell
Michael Thomas HendersonDirector2026-05-0824,814$74.76
$1.86MSell
Michael Thomas HendersonDirector2026-05-0833,513$73.72
$2.47MSell
Cameron TurtleChief Executive Officer2026-05-01300$74.96
$22.49kSell
Scott L. BurrowsChief Financial Officer2026-05-0112,500$14.50
$181.25kBuy
Scott L. BurrowsChief Financial Officer2026-05-0112,500$71.37
$892.13kSell
Sheldon SloanChief Medical Officer2026-05-0178,333$27.46
$2.15MBuy
Sheldon SloanChief Medical Officer2026-05-0121,306$69.53
$1.48MSell
Sheldon SloanChief Medical Officer2026-05-0119,656$70.61
$1.39MSell

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Net Insider Buy/Sell (L12M) Ownership

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SYRE Shareholders

What type of owners hold Spyre Therapeutics Inc stock?

Institutional
Insider
Retail
NameHoldSharesValueType
Fairmount Funds Management LLC16.47%14,301,760$1.08BInsider
Baker Bros Advisors LP3.56%3,094,590$234.11MInsider
Vanguard Capital Management LLC3.52%3,057,401$231.29MInstitution
Orbimed Advisors LLC3.26%2,829,748$214.07MInsider
Novartis Bioventures Ltd2.50%2,175,314$164.56MInsider
Anthony G. Quinn1.18%1,025,680$77.59MInsider
Ubs Group Ag0.77%671,235$50.78MInstitution
Emerald Advisers LLC0.71%613,365$46.40MInstitution
Cameron Turtle0.71%612,540$46.34MInsider
Candriam Sca0.70%610,282$46.17MInstitution

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SYRE vs Biotech Stocks

TickerInst. %Insider %Net Insider (L12M)Net Insider (L3M)
SYRE10.33%29.57%Net SellingNet Selling
PTGX22.36%22.68%Net SellingNet Selling
CELC11.45%24.19%Net BuyingNet Selling
KYMR15.05%32.56%Net BuyingNet Selling
TECH34.96%2.51%Net SellingNet Selling
View Top Biotech Stocks

Spyre Therapeutics Stock Ownership FAQ

Who owns Spyre Therapeutics?

Spyre Therapeutics (NASDAQ: SYRE) is owned by 10.33% institutional shareholders, 29.57% Spyre Therapeutics insiders, and 60.10% retail investors. Fairmount Funds Management LLC is the largest individual Spyre Therapeutics shareholder, owning 14.30M shares representing 16.47% of the company. Fairmount Funds Management LLC's Spyre Therapeutics shares are currently valued at $1.07B.

If you're new to stock investing, here's how to buy Spyre Therapeutics stock.
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