NASDAQ: SYRE
Spyre Therapeutics Inc Stock Ownership - Who owns Spyre Therapeutics?

Insider buying vs selling

Have Spyre Therapeutics Inc insiders been buying or selling?

Buy
Sell
NameRoleDateSharesPriceValue
Scott L. BurrowsChief Financial Officer2026-03-03200$41.66
$8.33kSell
Scott L. BurrowsChief Financial Officer2026-03-032,300$40.56
$93.29kSell
Scott L. BurrowsChief Financial Officer2026-03-032,500$14.50
$36.25kBuy
Cameron TurtleChief Executive Officer2026-03-029,100$42.49
$386.66kSell
Cameron TurtleChief Executive Officer2026-03-025,900$41.73
$246.21kSell
Cameron TurtleChief Executive Officer2026-02-0214,043$32.87
$461.59kSell
Cameron TurtleChief Executive Officer2026-02-02957$31.82
$30.45kSell
Cameron TurtleChief Executive Officer2026-01-022,191$31.79
$69.65kSell
Cameron TurtleChief Executive Officer2026-01-0212,709$30.47
$387.24kSell
Cameron TurtleChief Executive Officer2026-01-02100$32.39
$3.24kSell

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Net Insider Buy/Sell (L12M) Ownership

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SYRE Shareholders

What type of owners hold Spyre Therapeutics Inc stock?

Institutional
Insider
Retail
NameHoldSharesValueType
Fairmount Funds Management LLC18.21%14,301,760$653.30MInsider
Fmr LLC14.82%11,638,819$531.66MInstitution
Blackrock Inc7.03%5,522,101$252.25MInstitution
Rtw Investments LP5.31%4,171,996$190.58MInstitution
Vanguard Group Inc5.14%4,035,074$184.32MInstitution
Fairmount Funds Management LLC5.12%4,018,101$183.55MInstitution
Vr Adviser LLC4.69%3,685,448$168.35MInstitution
Capital International Investors4.45%3,492,541$159.54MInstitution
Baker Bros Advisors LP3.94%3,094,590$141.36MInsider
Perceptive Advisors LLC3.91%3,069,225$140.20MInstitution

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SYRE vs Biotech Stocks

TickerInst. %Insider %Net Insider (L12M)Net Insider (L3M)
SYRE75.85%24.15%Net SellingNet Selling
DNTH59.29%40.71%Net BuyingNet Buying
CRNX89.56%10.44%Net BuyingNet Selling
ACAD72.02%27.98%Net SellingNet Selling
NAMS74.47%25.53%Net SellingNet Selling

Spyre Therapeutics Stock Ownership FAQ

Who owns Spyre Therapeutics?

Spyre Therapeutics (NASDAQ: SYRE) is owned by 103.10% institutional shareholders, 32.83% Spyre Therapeutics insiders, and 0.00% retail investors. Fairmount Funds Management LLC is the largest individual Spyre Therapeutics shareholder, owning 14.30M shares representing 18.21% of the company. Fairmount Funds Management LLC's Spyre Therapeutics shares are currently valued at $679.62M.

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