NASDAQ: SYRE
Spyre Therapeutics Inc Stock Ownership - Who owns Spyre Therapeutics?

Insider buying vs selling

Have Spyre Therapeutics Inc insiders been buying or selling?

Buy
Sell
NameRoleDateSharesPriceValue
Heidy KingjonesCLO;Sec2026-10-01400$89.24
$35.70kSell
Scott L. BurrowsCFO2026-10-01229$93.57
$21.43kSell
Scott L. BurrowsCFO2026-10-013,071$92.95
$285.45kSell
Scott L. BurrowsCFO2026-10-012,100$91.92
$193.03kSell
Scott L. BurrowsCFO2026-10-011,500$90.27
$135.41kSell
Cameron TurtleCEO2026-10-014,990$93.37
$465.92kSell
Cameron TurtleCEO2026-10-013,989$92.31
$368.22kSell
Cameron TurtleCEO2026-10-012,638$91.49
$241.35kSell
Cameron TurtleCEO2026-10-012,683$90.10
$241.74kSell
Cameron TurtleCEO2026-10-01600$89.14
$53.48kSell

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Net Insider Buy/Sell (L12M) Ownership

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SYRE Shareholders

What type of owners hold Spyre Therapeutics Inc stock?

Institutional
Insider
Retail
NameHoldSharesValueType
Fairmount Funds Management LLC10.83%10,283,659$1.07BInsider
Baker Bros Advisors LP3.26%3,094,590$321.40MInsider
Orbimed Advisors LLC2.98%2,829,748$293.90MInsider
Novartis Bioventures Ltd2.29%2,175,314$225.93MInsider
Anthony G. Quinn1.08%1,025,680$106.53MInsider
Cameron Turtle0.57%537,540$55.83MInsider
George Georgiou0.47%446,337$46.36MInsider
David George Lowe0.22%212,040$22.02MInsider
Armen Shanafelt0.22%207,619$21.56MInsider
Jonathan Alspaugh0.17%165,372$17.18MInsider

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SYRE vs Biotech Stocks

TickerInst. %Insider %Net Insider (L12M)Net Insider (L3M)
SYRE0.10%22.70%Net SellingNet Selling
PCVX0.11%12.80%Net SellingNet Selling
MDGL0.03%99.97%Net BuyingNet Buying
TGTX0.07%48.64%Net SellingNet Selling
IBRX0.02%7.21%Net BuyingNet Selling

Spyre Therapeutics Stock Ownership FAQ

Who owns Spyre Therapeutics?

Spyre Therapeutics (NASDAQ: SYRE) is owned by 0.10% institutional shareholders, 22.70% Spyre Therapeutics insiders, and 77.20% retail investors. Fairmount Funds Management LLC is the largest individual Spyre Therapeutics shareholder, owning 10.28M shares representing 10.83% of the company. Fairmount Funds Management LLC's Spyre Therapeutics shares are currently valued at $1.07B.

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