NASDAQ: SYRE
Spyre Therapeutics Inc Stock Ownership - Who owns Spyre Therapeutics?

Insider buying vs selling

Have Spyre Therapeutics Inc insiders been buying or selling?

Buy
Sell
NameRoleDateSharesPriceValue
Jeffrey W. AlbersDirector2026-08-075,000$104.47
$522.35kSell
Jeffrey W. AlbersDirector2026-08-078,000$104.38
$835.04kSell
Jeffrey W. AlbersDirector2026-08-0710,000$104.68
$1.05MSell
Jeffrey W. AlbersDirector2026-08-075,000$10.39
$51.95kBuy
Scott L. BurrowsCFO2026-08-037,500$14.50
$108.75kBuy
Cameron TurtleCEO2026-08-031,392$96.82
$134.77kSell
Cameron TurtleCEO2026-08-035,635$95.93
$540.57kSell
Cameron TurtleCEO2026-08-037,157$95.10
$680.63kSell
Cameron TurtleCEO2026-08-03800$93.97
$75.18kSell
Scott L. BurrowsCFO2026-08-03100$97.10
$9.71kSell

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Net Insider Buy/Sell (L12M) Ownership

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SYRE Shareholders

What type of owners hold Spyre Therapeutics Inc stock?

Institutional
Insider
Retail
NameHoldSharesValueType
Fmr LLC13.36%11,781,024$1.24BInstitution
Fairmount Funds Management LLC11.66%10,283,659$1.08BInsider
Blackrock Inc6.26%5,521,221$581.55MInstitution
Rtw Investments LP4.73%4,171,996$439.44MInstitution
Fairmount Funds Management LLC4.56%4,018,101$423.23MInstitution
Perceptive Advisors LLC4.29%3,783,225$398.49MInstitution
Venrock Adviser LLC4.18%3,685,448$388.19MInstitution
Baker Bros Advisors LP3.51%3,094,590$325.95MInsider
Vanguard Capital Management LLC3.47%3,057,401$322.04MInstitution
Orbimed Advisors LLC3.21%2,829,748$298.06MInsider

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SYRE vs Biotech Stocks

TickerInst. %Insider %Net Insider (L12M)Net Insider (L3M)
SYRE79.28%20.72%Net SellingNet Selling
KYMR78.37%21.63%Net SellingNet Selling
CRNX89.67%10.33%Net SellingNet Buying
IONS96.88%3.12%Net SellingNet Selling
PCVX88.92%11.08%Net SellingNet Selling

Spyre Therapeutics Stock Ownership FAQ

Who owns Spyre Therapeutics?

Spyre Therapeutics (NASDAQ: SYRE) is owned by 93.73% institutional shareholders, 24.50% Spyre Therapeutics insiders, and 0.00% retail investors. Fairmount Funds Management LLC is the largest individual Spyre Therapeutics shareholder, owning 10.28M shares representing 11.66% of the company. Fairmount Funds Management LLC's Spyre Therapeutics shares are currently valued at $1.06B.

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