NASDAQ: SYRE
Spyre Therapeutics Inc Stock Ownership - Who owns Spyre Therapeutics?

Insider buying vs selling

Have Spyre Therapeutics Inc insiders been buying or selling?

Buy
Sell
NameRoleDateSharesPriceValue
Scott L. BurrowsCFO2026-09-0218,232$89.35
$1.63MSell
Heidy KingjonesOfficer2026-09-02400$14.50
$5.80kBuy
Heidy KingjonesOfficer2026-09-02400$90.00
$36.00kSell
Cameron TurtleCEO2026-09-01400$89.07
$35.63kSell
Cameron TurtleCEO2026-09-013,700$88.06
$325.82kSell
Cameron TurtleCEO2026-09-018,400$87.15
$732.06kSell
Cameron TurtleCEO2026-09-012,500$86.36
$215.90kSell
Scott L. BurrowsCFO2026-09-012,016$88.03
$177.47kSell
Heidy KingjonesOfficer2026-09-014,845$86.40
$418.61kSell
Heidy KingjonesOfficer2026-09-0127,999$14.50
$405.99kBuy

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Net Insider Buy/Sell (L12M) Ownership

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SYRE Shareholders

What type of owners hold Spyre Therapeutics Inc stock?

Institutional
Insider
Retail
NameHoldSharesValueType
Fairmount Funds Management LLC11.66%10,283,659$946.41MInsider
Baker Bros Advisors LP3.51%3,094,590$284.80MInsider
Orbimed Advisors LLC3.21%2,829,748$260.42MInsider
Novartis Bioventures Ltd2.47%2,175,314$200.19MInsider
Anthony G. Quinn1.16%1,025,680$94.39MInsider
Cameron Turtle0.63%552,540$50.85MInsider
George Georgiou0.51%446,337$41.08MInsider
David George Lowe0.24%212,040$19.51MInsider
Armen Shanafelt0.24%207,619$19.11MInsider
Jonathan Alspaugh0.19%165,372$15.22MInsider

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SYRE vs Biotech Stocks

TickerInst. %Insider %Net Insider (L12M)Net Insider (L3M)
SYRE0.11%24.47%Net SellingNet Selling
ABVX0.07%0.00%
PRAX0.12%50.28%Net SellingNet Buying
IMVT0.05%57.73%Net BuyingNet Selling
IONS0.11%3.35%Net SellingNet Selling

Spyre Therapeutics Stock Ownership FAQ

Who owns Spyre Therapeutics?

Spyre Therapeutics (NASDAQ: SYRE) is owned by 0.11% institutional shareholders, 24.47% Spyre Therapeutics insiders, and 75.42% retail investors. Fairmount Funds Management LLC is the largest individual Spyre Therapeutics shareholder, owning 10.28M shares representing 11.66% of the company. Fairmount Funds Management LLC's Spyre Therapeutics shares are currently valued at $945.79M.

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