| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Rebecca Taub | Director | 2026-01-26 | 647 | $492.42 | $318.60kSell |
| William John Sibold | President and CEO | 2026-01-26 | 1,577 | $492.42 | $776.55kSell |
| Carole Huntsman | Chief Commercial Officer | 2026-01-26 | 340 | $492.42 | $167.42kSell |
| Carole Huntsman | Chief Commercial Officer | 2026-01-26 | 570 | $494.59 | $281.92kSell |
| Richard S. Levy | Director | 2026-01-26 | 4,000 | $16.46 | $65.84kBuy |
| Shannon T. Kelley | General Counsel | 2026-01-20 | 429 | $501.40 | $215.10kSell |
| Shannon T. Kelley | General Counsel | 2026-01-20 | 263 | $490.77 | $129.07kSell |
| Rebecca Taub | Director | 2026-01-20 | 2,238 | $490.77 | $1.10MSell |
| Paul A. Friedman | Director | 2026-01-09 | 280 | $530.69 | $148.59kSell |
| Paul A. Friedman | Director | 2026-01-09 | 80 | $532.50 | $42.60kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Bruce Kovner | 99.99% | 22,937,805 | $9.98B | Insider |
| Cxsynta LLC | 33.83% | 7,761,716 | $3.38B | Insider |
| Lan Bo Chen | 26.78% | 6,142,288 | $2.67B | Insider |
| Fred B. Craves | 26.33% | 6,040,140 | $2.63B | Insider |
| Lin Huey Chen | 26.12% | 5,991,757 | $2.61B | Insider |
| Bay City Capital LLC | 25.05% | 5,747,267 | $2.50B | Insider |
| Safi R. Bahcall | 12.29% | 2,818,885 | $1.23B | Insider |
| Keith R. Gollust | 9.99% | 2,290,933 | $996.58M | Insider |
| Baker Bros Advisors LP | 9.34% | 2,141,701 | $931.66M | Institution |
| Rtw Investments LP | 8.69% | 1,993,687 | $867.27M | Institution |