| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Asit Parikh | Director | 2025-12-19 | 8,750 | $10.30 | $90.13kBuy |
| Robert Charles Breedlove | Principal Accounting Officer | 2025-12-18 | 230 | $16.28 | $3.74kSell |
| Steven L. Basta | President and CEO | 2025-12-17 | 31,502 | $15.36 | $483.87kSell |
| Anne Marie Cook | Chief Legal Off. Corp. Sec. | 2025-12-17 | 7,703 | $15.36 | $118.32kSell |
| Steven L. Basta | President and CEO | 2025-11-28 | 48,375 | $15.62 | $755.62kSell |
| Robert Charles Breedlove | Principal Accounting Officer | 2025-11-03 | 524 | $13.51 | $7.08kSell |
| Steven L. Basta | President and CEO | 2025-09-25 | 48,375 | $11.66 | $564.05kSell |
| Robert Charles Breedlove | Principal Accounting Officer | 2025-09-05 | 461 | $12.09 | $5.57kSell |
| Robert Charles Breedlove | Principal Accounting Officer | 2025-07-16 | 1,692 | $8.36 | $14.15kSell |
| James N. Topper | Director | 2025-05-21 | 3,780 | $3.87 | $14.61kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Frazier Life Sciences Management LP | 17.52% | 12,466,489 | $218.91M | Institution |
| Medicxi Ventures Management Jersey Ltd | 10.49% | 7,464,572 | $131.08M | Insider |
| Medicxi Ventures Management Jersey Ltd | 10.49% | 7,464,572 | $131.08M | Institution |
| James N. Topper | 8.35% | 5,937,240 | $104.26M | Insider |
| Frazier Life Sciences IX LP | 8.21% | 5,842,352 | $102.59M | Insider |
| Millennium Management LLC | 7.14% | 5,081,451 | $89.23M | Institution |
| Invesco Ltd | 5.43% | 3,864,971 | $67.87M | Institution |
| Takeda Pharmaceutical Co Ltd | 5.28% | 3,755,583 | $65.95M | Insider |
| Carlyle Group Inc | 4.92% | 3,496,808 | $61.40M | Institution |
| Blackrock Inc | 4.78% | 3,402,324 | $59.74M | Institution |