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Best Biotech Stocks to Buy Now (2026)

Top biotech stocks in 2026 ranked by overall Zen Rating. "A" Rated stocks have returned an average of +32.52% per year, and are the best biotech stocks to buy now. Learn More.

According to Zen Ratings, our proprietary rating system that evaluates 115 factors proven to drive growth in stocks and assigns each stock in our system an overall letter grade as well as 7 individual Component Grades for Value, Growth, Momentum, Sentiment, Safety, Financials, and proprietary AI algorithms, the 3 best biotechnology stocks to buy right now are:

Jazz Pharmaceuticals (NASDAQ:JAZZ) is the #1 top biotech stock out of 607 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Jazz Pharmaceuticals (NASDAQ:JAZZ) is: Value: A, Growth: A, Momentum: B, Sentiment: C, Safety: C, Financials: B, and AI: C.

Jazz Pharmaceuticals (NASDAQ:JAZZ) has a Due Diligence Score of 27, which is 2 points higher than the biotech industry average of 25.

JAZZ passed 9 out of 33 due diligence checks and has average fundamentals. Jazz Pharmaceuticals has seen its stock return 129.44% over the past year, overperforming other biotech stocks by 132 percentage points.

Jazz Pharmaceuticals has an average 1 year price target of $237.67, an upside of 5.26% from Jazz Pharmaceuticals's current stock price of $225.79.

Jazz Pharmaceuticals stock has a consensus Strong Buy recommendation according to Wall Street analysts. Of the 12 analysts covering Jazz Pharmaceuticals, 58.33% have issued a Strong Buy rating, 33.33% have issued a Buy, 8.33% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

Exelixis (NASDAQ:EXEL) is the #2 top biotech stock out of 607 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Exelixis (NASDAQ:EXEL) is: Value: A, Growth: B, Momentum: C, Sentiment: B, Safety: C, Financials: A, and AI: B.

Exelixis (NASDAQ:EXEL) has a Due Diligence Score of 52, which is 27 points higher than the biotech industry average of 25.

EXEL passed 17 out of 33 due diligence checks and has strong fundamentals. Exelixis has seen its stock return 31.95% over the past year, overperforming other biotech stocks by 34 percentage points.

Exelixis has an average 1 year price target of $48.00, a downside of -0.33% from Exelixis's current stock price of $48.16.

Exelixis stock has a consensus Buy recommendation according to Wall Street analysts. Of the 7 analysts covering Exelixis, 14.29% have issued a Strong Buy rating, 14.29% have issued a Buy, 71.43% have issued a hold, while 0% have issued a Sell rating, and 0% have issued a Strong Sell.

Puma Biotechnology (NASDAQ:PBYI) is the #3 top biotech stock out of 607 with a Zen Rating of A. Stocks with a rating of A have had an average return of +32.52% per year. Learn more.

The Component Grade breakdown for Puma Biotechnology (NASDAQ:PBYI) is: Value: A, Growth: C, Momentum: B, Sentiment: A, Safety: C, Financials: B, and AI: C.

Puma Biotechnology (NASDAQ:PBYI) has a Due Diligence Score of 56, which is 31 points higher than the biotech industry average of 25.

PBYI passed 18 out of 33 due diligence checks and has strong fundamentals. Puma Biotechnology has seen its stock return 143.97% over the past year, overperforming other biotech stocks by 146 percentage points.

Out of 6 biotech stocks that have issued dividends in the past year, the 3 biotech stocks with the highest dividend yields are:

Dominari Holdings (NASDAQ:DOMH) has an annual dividend yield of 18.27%, which is 14 percentage points higher than the biotech industry average of 4.3%.

Dominari Holdings's dividend payout ratio of -42.4% indicates that its high dividend yield might not be sustainable for the long-term.

Oramed Pharmaceuticals (NASDAQ:ORMP) has an annual dividend yield of 6.11%, which is 2 percentage points higher than the biotech industry average of 4.3%.

Oramed Pharmaceuticals's dividend payout ratio of 16.3% indicates that its high dividend yield is sustainable for the long-term.

Novo Nordisk (Ozempic) (NYSE:NVO) has an annual dividend yield of 2.77%, which is -2 percentage points lower than the biotech industry average of 4.3%. Novo Nordisk (Ozempic)'s dividend payout is not stable, having dropped more than 10% nine times in the last 10 years. Novo Nordisk (Ozempic)'s dividend has shown consistent growth over the last 10 years.

Novo Nordisk (Ozempic)'s dividend payout ratio of 43.1% indicates that its dividend yield is sustainable for the long-term.

Biotech stocks were up 0.17% in the last day, and up 2.15% over the last week. Traws Pharma was the among the top gainers in the biotechnology industry, gaining 28.24% yesterday.

Traws Pharma shares are trading higher after the company announced plans to advance potential clinical candidates for the treatment of hantavirus infections.

Based on the Valuation rating, one of the 7 components of a stocks overall Zen Ratings grade, which evaluates factors including estimated earnings yield, earnings before interest and taxes/enterprise value, cash flow yield, free cash flow to price, and price-to-earnings growth (PEG ratio), the 3 most undervalued biotech stocks right now are:

Rigel Pharmaceuticals (NASDAQ:RIGL) is the most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Rigel Pharmaceuticals has a valuation score of 43, which is 30 points higher than the biotech industry average of 13. It passed 3 out of 7 valuation due diligence checks.

Rigel Pharmaceuticals's stock has gained 37.78% in the past year. It has overperformed other stocks in the biotech industry by 40 percentage points.

Incyte (NASDAQ:INCY) is the second most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Incyte has a valuation score of 71, which is 58 points higher than the biotech industry average of 13. It passed 5 out of 7 valuation due diligence checks.

Incyte's stock has gained 65.01% in the past year. It has overperformed other stocks in the biotech industry by 67 percentage points.

Harmony Biosciences Holdings (NASDAQ:HRMY) is the third most undervalued biotech stock based on its Valuation Rating of A. Valuation is one of 7 Component Grades used to calculate the overall Zen Rating.

Harmony Biosciences Holdings has a valuation score of 71, which is 58 points higher than the biotech industry average of 13. It passed 5 out of 7 valuation due diligence checks.

Harmony Biosciences Holdings's stock has dropped -9.09% in the past year. It has underperformed other stocks in the biotech industry by -7 percentage points.

65.08% of biotech stocks rated by analysts are a strong buy right now. On average, analysts expect biotech stocks to rise by 61.11% over the next year.

3.09% of biotech stocks have a Zen Rating of A (Strong Buy), 3.75% of biotech stocks are rated B (Buy), 47.46% are rated C (Hold), 34.44% are rated D (Sell), and 11.26% are rated F (Strong Sell).