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NASDAQ: SEPN
Septerna Inc Stock Forecast, Predictions & Price Target

OverviewForecast
EarningsRevenueDividendOwnership

Analyst price target for SEPN

Based on 7 analysts offering 12 month price targets for Septerna Inc

Min Forecast
$43.00+8.72%
Avg Forecast
$52.43+32.56%
Max Forecast
$62.00+56.76%

Should I buy or sell SEPN stock?

Based on 7 analysts offering ratings for Septerna Inc.

Strong Buy
Strong Buy
6 analysts 85.71%
Buy
1 analysts 14.29%
Hold
0 analysts 0%
Sell
0 analysts 0%
Strong Sell
0 analysts 0%
Although SEPN's forecast from analysts indicates a "Strong Buy", our proven Zen Rating quant model rates SEPN as a "Hold". Stocks with a Zen Rating of Hold have had an average return of +5.11% per year. Learn More

Be the first to know when Wall Street analysts revise their SEPN stock forecasts and price targets.

SEPN stock forecasts by analyst

Analyst / FirmRatingActionPrice TargetUpside/DownsideDateAnalyst Color
lockedlocked$00.00+00.00%2026-08-19
lockedlocked$00.00+00.00%2026-08-13Find Out Why
lockedlocked$00.00+00.00%2026-08-12
lockedlocked$00.00+00.00%2026-08-12
lockedlocked$00.00+00.00%2026-08-11Find Out Why
Truist Securities
Top 8%
93
Strong BuyMaintains$43.00+8.72%2026-07-01Find out why
Raymond James
Top 17%
84
Strong BuyMaintains$53.00+34.01%2026-06-08Find out why

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Forecast return on equity

Is SEPN forecast to generate an efficient return?

Company
-38.9%
Industry
19.68%
Market
168.87%
SEPN's Return on Equity is... subscribe to Premium to read more.
Forecast High Return on Equity Forecast

Forecast return on assets

Is SEPN forecast to generate an efficient return on assets?

Company
-26.55%
Industry
23.53%
SEPN is forecast to generate... subscribe to Premium to read more.
Forecast Return on Assets vs Industry Forecast

SEPN earnings per share forecast

What is SEPN's earnings per share in the next 3 years based on estimates from 12 analysts?

Avg 1 year Forecast
-$1.61
Avg 2 year Forecast
-$2.31
Avg 3 year Forecast
-$3.05

SEPN revenue forecast

What is SEPN's revenue in the next 3 years based on estimates from 12 analysts?

Avg 1 year Forecast
$98.0M-0.93%
Avg 2 year Forecast
$83.4M-15.62%
Avg 3 year Forecast
$68.3M-30.89%
SEPN's revenue is forecast to... subscribe to Premium to read more.
Forecast High Revenue Growth Forecast

SEPN revenue growth forecast

How is SEPN forecast to perform vs Biotechnology companies and vs the US market?

Company
-11.53%
Industry
32.68%
Market
13.54%
SEPN's revenues are forecast to... subscribe to Premium to read more.
Forecast Revenue Growth vs Industry Forecast
SEPN's revenues are forecast to... subscribe to Premium to read more.
Forecast Revenue Growth vs Market Forecast

SEPN vs Biotech Stocks

TickerPricePrice TargetUp/downsideConsensus
SEPN$39.55$52.43+32.56%Strong Buy
RXRX$3.41$7.83+129.71%Buy
XNCR$24.53$31.86+29.87%Strong Buy
VIR$10.77$24.00+122.94%Strong Buy
COAG$40.47$51.40+27.01%Strong Buy
View Top Biotech Stocks

Septerna Stock Forecast FAQ

Is Septerna Stock a good buy in 2026, according to Wall Street analysts?

The consensus among 7 Wall Street analysts covering (NASDAQ: SEPN) stock is to Strong Buy SEPN stock.

Out of 7 analysts, 6 (85.71%) are recommending SEPN as a Strong Buy, 1 (14.29%) are recommending SEPN as a Buy, 0 (0%) are recommending SEPN as a Hold, 0 (0%) are recommending SEPN as a Sell, and 0 (0%) are recommending SEPN as a Strong Sell.

If you're new to stock investing, here's how to buy Septerna stock.

What is SEPN's earnings growth forecast for 2026-2028?

(NASDAQ: SEPN) Septerna's forecast annual earnings growth rate of N/A is not forecast to beat the US Biotechnology industry's average forecast earnings growth rate of 11.23%, and while it is not forecast to beat the US market's average forecast earnings growth rate of 31.19%.

Septerna's earnings in 2026 is -$24,236,000.On average, 12 Wall Street analysts forecast SEPN's earnings for 2026 to be -$75,014,522, with the lowest SEPN earnings forecast at -$152,325,549, and the highest SEPN earnings forecast at -$41,169,067. On average, 12 Wall Street analysts forecast SEPN's earnings for 2027 to be -$107,968,446, with the lowest SEPN earnings forecast at -$167,878,308, and the highest SEPN earnings forecast at -$66,654,680.

In 2028, SEPN is forecast to generate -$142,294,673 in earnings, with the lowest earnings forecast at -$212,249,413 and the highest earnings forecast at -$85,768,890.

What is SEPN's revenue growth forecast for 2026-2028?

(NASDAQ: SEPN) Septerna's forecast annual revenue growth rate of -11.53% is not forecast to beat the US Biotechnology industry's average forecast revenue growth rate of 32.68%, and while it is not forecast to beat the US market's average forecast revenue growth rate of 13.54%.

Septerna's revenue in 2026 is $98,882,000.On average, 12 Wall Street analysts forecast SEPN's revenue for 2026 to be $4,572,707,113, with the lowest SEPN revenue forecast at $2,438,123,650, and the highest SEPN revenue forecast at $5,783,273,733. On average, 12 Wall Street analysts forecast SEPN's revenue for 2027 to be $3,894,537,750, with the lowest SEPN revenue forecast at $0, and the highest SEPN revenue forecast at $6,028,327,705.

In 2028, SEPN is forecast to generate $3,189,902,558 in revenue, with the lowest revenue forecast at $1,601,019,282 and the highest revenue forecast at $4,410,971,492.

What is SEPN's forecast return on assets (ROA) for 2026-2029?

(NASDAQ: SEPN) forecast ROA is -26.55%, which is lower than the forecast US Biotechnology industry average of 23.53%.

What is SEPN's Price Target?

According to 7 Wall Street analysts that have issued a 1 year SEPN price target, the average SEPN price target is $52.43, with the highest SEPN stock price forecast at $62.00 and the lowest SEPN stock price forecast at $43.00.

On average, Wall Street analysts predict that Septerna's share price could reach $52.43 by Aug 19, 2027. The average Septerna stock price prediction forecasts a potential upside of 32.56% from the current SEPN share price of $39.55.

What is SEPN's Earnings Per Share (EPS) forecast for 2026-2028?

(NASDAQ: SEPN) Septerna's current Earnings Per Share (EPS) is -$0.54. On average, analysts forecast that SEPN's EPS will be -$1.61 for 2026, with the lowest EPS forecast at -$3.26, and the highest EPS forecast at -$0.88. On average, analysts forecast that SEPN's EPS will be -$2.31 for 2027, with the lowest EPS forecast at -$3.60, and the highest EPS forecast at -$1.43. In 2028, SEPN's EPS is forecast to hit -$3.05 (min: -$4.55, max: -$1.84).

What is SEPN's forecast return on equity (ROE) for 2026-2029?

(NASDAQ: SEPN) forecast ROE is -38.9%, which is considered weak.
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