NASDAQ: SEPN
Septerna Inc Earnings Dates, Reports, Calls

Septerna earnings were -$24.2M for the trailing 12 months ending Jun 30, 2026, with N/A growth year over year. The latest SEPN earnings report on Jun 30, 2026 announced Q2 2026 earnings of -$13.0M, up 50.9% from last quarter. For the last reported fiscal year 2025 ending Dec 31, 2025, SEPN reported annual earnings of -$48.9M, with -31.9% growth. The next SEPN earnings date is Nov 9, 2026.

SEPN earnings history

Current Revenue
$98.9M
Current Earnings
-$24.2M
Current Profit Margin
-24.5%

SEPN Return on Equity

Current Company
-6.3%
Current Industry
-10.8%
Current Market
30.9%
SEPN's Return on Equity (-6.3%)... subscribe to Premium to read more.
High Return on Equity Performance

SEPN Return on Assets

Current Company
-4.1%
Current Industry
-10.7%
SEPN is generating higher Return... subscribe to Premium to read more.
Above Average Return on Assets Performance

Be the first to know when SEPN announces earnings.

SEPN Return on Capital Employed

Current Company
-4.7%
Current Industry
-7.4%

SEPN vs Biotech Stocks

TickerEBITDAEarningsY/Y EarningsEPS
SEPN-$19.06M-$24.24MN/A-$0.54
GENBN/AN/AN/AN/A
ZYME-$133.34M-$149.99MN/A-$2.02
NVAX-$205.59M-$247.73MN/A-$1.52
NTLA-$384.74M-$399.98MN/A-$3.35

SEPN earnings dates

Next earnings date
Nov 9, 2026

Septerna Earnings Reports & History FAQ

What were Septerna's earnings last quarter?

On SEPN's earnings call on Aug 10, 2026, Septerna (NASDAQ: SEPN) reported Q2 2026 earnings per share (EPS) of -$0.29, up 48.21% year over year. Total SEPN earnings for the quarter were -$13.03 million. In the same quarter last year, Septerna's earnings per share (EPS) was -$0.56.

If you're new to stock investing, here's how to buy Septerna stock.

When does Septerna report earnings?

The next SEPN earnings call is Nov 9, 2026. Add SEPN to your watchlist to be reminded of Septerna's next earnings date.

Is Septerna profitable or losing money?

As of the last Septerna earnings report, Septerna is currently losing money. Septerna's net profit (also called net income) for the twelve months ending Jun 30, 2026 was -$24.24 million, a 72.3% decrease year over year.

What was SEPN's earnings growth in the past year?

As of Septerna's earnings date in Aug 10, 2026, Septerna's earnings has grown year over year. SEPN earnings in the past year totalled -$24.24 million.

What are Septerna's earnings expectations?

The current EPS estimate for Septerna's earnings report in Nov 9, 2026 is -$0.55.
WallStreetZen does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.

Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.