How to Buy Septerna Stock

Septerna Inc

Septerna, Inc. , a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products candidates for the treatment of endocrinology, immunology and inflammation, and metabolic diseases.

Septerna stock last closed at $23.87, down 3.52% from the previous day, and has increased 279.49% in one year. It has overperformed other stocks in the Biotechnology industry by 3.19 percentage points. Septerna stock is currently +412.23% from its 52-week low of $4.66, and -26.85% from its 52-week high of $32.63.

As of Mar 27, 2026, there are 44.91M shares of SEPN outstanding. The market capitalization of SEPN is $1.07B. In the last 24 hours, 145,000 SEPN shares were traded.

How to Buy Septerna Stock

Wondering how to invest in Septerna stock? Here's how.

  1. Figure out where to buy Septerna stock: You need to decide on an online brokerage, but don't worry - we've tested dozens of stock brokerages and apps to help you choose where to buy Septerna stock.
  2. Create your brokerage account: Sign up for 0% fee trading with the highest-rated brokerage we've identified.
  3. Put funds into your investment account: Pick your method of payment and add your details.
  4. Analyze Septerna stock: The Septerna ticker symbol is SEPN. Is Septerna stock a good investment? Should you buy shares of SEPN? How do SEPN's underlying business fundamentals look? Do top analysts think Septerna is a good buy? Why has SEPN's stock price moved recently? (Hint: Our stock market analysis tools can help you decide if SEPN is a good stock to buy).
  5. Place your SEPN trade: Decide if you will purchase SEPN shares at the current market price or use a limit order to buy SEPN shares at a specific price.
  6. Track your investment in SEPN: Create a watchlist to keep track of your position in Septerna shares.

Step 1: Figure out where to buy Septerna stock

You will need an online brokerage account to access the NASDAQ market and buy SEPN shares.

A brokerage account is an investment account that enables you to buy and sell a variety of financial instruments, including stocks, bonds, mutual funds, and ETFs.

Our favorite brokerage: eToro

Based on our research, eToro is the best place to buy stocks. Here's why:

  • Invest in stocks with 0% commissions: Invest without paying trading commissions.
  • Buy fractional shares: Even if you can't afford a full share, you can still buy the stock.
  • Access to global financial markets: From Technology to Industrials, New York to Shanghai (for US users, only US stocks are available) — you can fill your portfolio with stocks from the globe's top stock exchanges.
  • Social investing: eToro boasts a community with more than 20 million users worldwide. Talk to, learn from, and copy the unique crypto portfolios of other investors.
  • Security: eToro is a regulated and licensed brokerage platform.
  • Buy other financial assets: Such as ETFs and cryptocurrencies.

Get $10 towards your purchase of stock by creating an account with eToro now. This offer is only for US users.

Open eToro Account
eToro securities trading is offered by eToro USA Securities, Inc. (“the BD”), member of FINRA and SIPC. Cryptocurrency is offered by eToro USA LLC (“the MSB”) (NMLS: 1769299) and is not FDIC or SIPC insured. Investing involves risk, and content is provided for educational purposes only, does not imply a recommendation, and is not a guarantee of future performance. https://www.wallstreetzen.com is not an affiliate and may be compensated if you access certain products or services offered by the MSB and/or the BD.

Step 2: Create your brokerage account

Now that you've picked your brokerage, it's time to fill out some personal info so you are able to invest in SEPN today.

How to Create a New Brokerage Account on eToro

  1. Click here to get started.
    eToro is a multi-asset investment platform. The value of your investments may go up or down. Your capital is at risk.
  2. Enter your personal details to start your new trading account.
  1. Send your data by hitting the "Create Account" button.
  2. Get started with eToro today
    eToro is a multi-asset investment platform. The value of your investments may go up or down. Your capital is at risk.

Step 3: Put funds into your investment account

Now that you have finished signing up on the best stock app, your next step is to transfer the money for your investment:

Check out the video below to see the process of depositing funds into your new investment account.

Get started with eToro today
eToro is a multi-asset investment platform. The value of your investments may go up or down. Your capital is at risk.

Step 4: Analyze Septerna stock

After you have figured out the best place to buy Septerna stock, it's very important to research their stock before you buy, so you truly understand the risk as well as the opportunity.

Septerna quick stats

SEPN Price
$23.87
1w %
-1.28%
1y %
279.49%
5y %
N/A
P/E
-21.7x
P/B
2.81x
P/S
23x
PEG
N/A
Revenue
$45.95M
Earnings
-$48.88M
Fore. Rev. Growth
11.95%
Fore. Earn. Growth
N/A
Market Cap
$1.07B
Next Earnings
May 14, 2026
Next Dividend
N/A

SEPN Fundamentals

WallStreetZen was created to help average investors perform more in-depth fundamental analysis in minutes instead of hours.

You can see all of the due diligence checks on SEPN's stock page.

What is the fair value of SEPN stock?

Investors use many financial metrics, analyses, models, and charts to gauge SEPN's intrinsic value.

Using relative valuations metrics:

  • SEPN could be undervalued based on its P/B ratio of 2.81x, relative to Biotechnology industry P/B ratio of 4.52x

You can access more valuation analysis on SEPN's stock here.

How do SEPN Financials look?

Passed Health Checks:

  • SEPN's operating cash flow of $110.19M allows it to safely service it's debt of $23.63M.
  • There are more short-term assets than long-term liabilities on the SEPN balance sheet.
  • There are more short-term assets than short-term liabilities on the SEPN balance sheet.

Failed Health Checks:

  • SEPN has a relatively high debt to equity ratio of 0.56.
  • SEPN earnings of -$48.87M is not enough to cover its interest payments.
  • SEPN profit margin has gone up by 65.73 percentage points in the past year, but the company is still unprofitable.

Do analysts think it's a good time to buy SEPN stock

Out of 6 Equities analysts who research SEPN, the consensus analyst rating on Septerna is a Strong Buy

Please note that analyst forecasts are not recommendations, nor are they investment advice.

Most Recent SEPN Analyst Forecasts

Martin Auster, a top 21% analyst from Raymond James initiates coverage on SEPN with a strong buy rating and announces their SEPN price target of $38.00, on Dec 19, 2025.

You can dive deeper into what analysts are saying on the Septerna stock forecast page.

SEPN Trading Indicators

SMA10
24.29
SMA20
25.99
SMA50
26.41
SMA100
25.81
SMA200
20.31
MACD
-0.94
MACD Signal
-0.71
MACD Histogram
-0.23
RSI
39.58
Stochastic %K
18.65
Stochastic %D
15.14
StochRSI %K
32.06
StochRSI %D
20.98

SEPN Growth Metrics

Last year, SEPN revenue was $45.95M. In the last two year, SEPN's revenue has increased by 1,644.45% per year. This was faster than the Biotechnology industry average of 29%.

You can research SEPN's earnings and revenue performance here.

Who is buying/selling SEPN?

In the last year, executives and large shareholders at SEPN have bought more shares than they have sold.

Samira Shaikhly, Chief People Officer of SEPN, was the latest SEPN insider to buy. They bought $83,256.70 worth of SEPN stock on Mar 2, 2026.

Dig into more about who owns SEPN stock here.

Does SEPN provide a stable income stream?

No, Septerna doesn't provide an income stream by paying out dividends.

Get opinions from other traders

One of the primary reasons eToro is our top-rated brokerage is because of its social trading community.

Click below to find out what other community members have to say.

Step 5: Place your SEPN trade

You have two primary order types:

  • Market order: A market order is an order to buy or sell a stock at the best price on the market.
    Market orders are generally fine.
  • Limit order: A limit order allows you to buy or sell a security at a specific price (or better).
    If you want to be certain you're buying or selling at an exact price limit, place a limit order.

Hit the Open button and your broker will place the order.

If you require additional info about buying stocks on eToro, watch the how to video below:

Open eToro Account

Step 6: Track your investment in SEPN

Now that you own some SEPN stock, you'll want to stay up-to-date on your investment.

Create a watchlist to get notified of important updates regarding your SEPN stock.

SEPN Feed

How to Buy Stock in Septerna

To summarize, here are the 6 steps for buying Septerna stock:

  1. Figure out where to buy Septerna stock
  2. Create your brokerage account
  3. Put funds into your investment account
  4. Analyze Septerna stock
  5. Place your SEPN trade
  6. Track your investment in SEPN

If you are looking for a online brokerage, eToro is our favorite option.

Get Started with eToro Today
eToro is a multi-asset investment platform. The value of your investments may go up or down. Your capital is at risk.

If you would like to get updates on your investment in Septerna, create a watchlist on WallStreetZen today.

NASDAQ: SEPN
$23.87-0.87 (-3.52%)
Updated Mar 27, 2026
Open eToro Account
Your capital is at risk.
NASDAQ: SEPN
$23.87-0.87 (-3.52%)
Updated Mar 27, 2026
Open eToro Account
Your capital is at risk.

FAQ

How much does it cost to buy one Septerna share?

As of Mar 27, 2026, it costs $23.87 to buy one share of Septerna stock.

Remember, eToro's fractional share buying allows you to buy partial shares of stocks and ETFs. Even if you only have $10, you can buy 0.419 shares of SEPN.

Get Started with eToro Today
eToro is a multi-asset investment platform. The value of your investments may go up or down. Your capital is at risk.

Is now a good time to buy Septerna stock?

According to 6 Wall Street analysts who monitor Septerna, their consensus recommendation is to buy Septerna stock.

What is the best way to buy Septerna stock?

One way to place an order for Septerna stock is with a brokerage account.
WallStreetZen does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.

Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.