| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Ra Capital Management LP | 16.83% | 10,281,496 | $2.06B | Institution |
| Westfield Capital Management Co LP | 8.61% | 5,259,909 | $1.05B | Institution |
| Avoro Capital Advisors LLC | 8.36% | 5,110,000 | $1.02B | Institution |
| Fmr LLC | 7.32% | 4,471,733 | $894.30M | Institution |
| Janus Henderson Group PLC | 7.08% | 4,323,059 | $864.57M | Institution |
| Lombard Odier Asset Management Europe Ltd | 6.99% | 4,269,000 | $853.76M | Institution |
| Artisan Partners Limited Partnership | 6.09% | 3,720,880 | $744.14M | Institution |
| Capital International Investors | 5.01% | 3,060,616 | $612.09M | Institution |
| T Rowe Price Investment Management Inc | 4.36% | 2,666,618 | $533.30M | Institution |
| Massachusetts Financial Services Co | 3.08% | 1,882,781 | $376.54M | Institution |