| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Fmr LLC | 10% Owner | 2025-10-27 | 459 | $26.68 | $12.25kSell |
| John M. Evans | CEO | 2025-10-02 | 25,000 | $24.63 | $615.68kSell |
| John M. Evans | CEO | 2025-10-02 | 25,000 | $0.67 | $16.75kBuy |
| John M. Evans | CEO | 2025-10-01 | 25,000 | $0.67 | $16.75kBuy |
| Christine Bellon | Chief Legal Officer | 2025-10-01 | 373 | $24.53 | $9.15kSell |
| Bethany J. Cavanagh | SVP Finance and Treasurer | 2025-10-01 | 467 | $24.53 | $11.46kSell |
| John M. Evans | CEO | 2025-10-01 | 25,000 | $24.51 | $612.65kSell |
| Fmr LLC | 10% Owner | 2025-07-30 | 48,374 | $20.50 | $991.67kSell |
| Amy Simon | Chief Medical Officer | 2025-07-03 | 876 | $20.12 | $17.63kSell |
| Amy Simon | Chief Medical Officer | 2025-07-01 | 374 | $16.94 | $6.34kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Fmr LLC | 12.81% | 12,961,459 | $324.17M | Institution |
| Farallon Capital Management LLC | 9.90% | 10,013,111 | $250.43M | Institution |
| Vanguard Group Inc | 9.59% | 9,706,224 | $242.75M | Institution |
| Ark Investment Management LLC | 8.75% | 8,847,841 | $221.28M | Institution |
| Blackrock Inc | 7.91% | 8,002,689 | $200.15M | Institution |
| Fmr LLC | 4.70% | 4,752,601 | $118.86M | Insider |
| Sumitomo Mitsui Trust Group Inc | 4.68% | 4,729,444 | $118.28M | Institution |
| Nikko Asset Management Americas Inc | 4.67% | 4,726,799 | $118.22M | Institution |
| Arch Venture Management LLC | 4.49% | 4,540,132 | $113.55M | Institution |
| State Street Corp | 3.60% | 3,638,266 | $90.99M | Institution |