| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Fairmount Funds Management LLC | Director | 2026-01-22 | 3,500,000 | $36.40 | $127.40MSell |
| Jessica Sachs | Chief Medical Officer | 2025-12-26 | 82,642 | $38.70 | $3.20MSell |
| John L. Green | Chief Financial Officer | 2025-12-26 | 77,000 | $38.68 | $2.98MSell |
| John Edward Robinson | Chief Scientific Officer | 2025-12-26 | 90,000 | $38.74 | $3.49MSell |
| Evan Kearns | Chief Legal Officer | 2025-12-26 | 65,000 | $38.70 | $2.52MSell |
| Jessica Sachs | Chief Medical Officer | 2025-12-17 | 154,716 | $39.45 | $6.10MSell |
| Cole Pinnow | Chief Commercial Officer | 2025-12-17 | 94,800 | $39.45 | $3.74MSell |
| John L. Green | Chief Financial Officer | 2025-12-17 | 145,007 | $39.45 | $5.72MSell |
| Evan Kearns | Chief Legal Officer | 2025-12-17 | 125,602 | $39.45 | $4.95MSell |
| Andrew R. Robbins | President and CEO | 2025-12-17 | 367,497 | $39.45 | $14.50MSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Fmr LLC | 14.22% | 23,086,967 | $862.07M | Institution |
| Blackrock Inc | 7.99% | 12,974,591 | $484.47M | Institution |
| Vanguard Group Inc | 7.09% | 11,514,326 | $429.94M | Institution |
| Deerfield Management Company LP | 5.57% | 9,043,903 | $337.70M | Institution |
| Fairmount Funds Management LLC | 5.55% | 9,003,418 | $336.19M | Institution |
| Rtw Investments LP | 4.68% | 7,592,241 | $283.49M | Institution |
| Kynam Capital Management LP | 3.80% | 6,165,223 | $230.21M | Institution |
| Tcg Crossover Management LLC | 3.62% | 5,868,162 | $219.12M | Institution |
| Fairmount Funds Management LLC | 3.39% | 5,503,418 | $205.50M | Insider |
| State Street Corp | 3.04% | 4,940,300 | $184.47M | Institution |