| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Fairmount Funds Management LLC | Director | 2026-03-31 | 7,000,000 | $34.66 | $242.62MSell |
| Fairmount Funds Management LLC | Director | 2026-01-22 | 3,500,000 | $36.40 | $127.40MSell |
| Jessica Sachs | Chief Medical Officer | 2025-12-26 | 82,642 | $38.70 | $3.20MSell |
| John L. Green | Chief Financial Officer | 2025-12-26 | 77,000 | $38.68 | $2.98MSell |
| Evan Kearns | Chief Legal Officer | 2025-12-26 | 65,000 | $38.70 | $2.52MSell |
| John Edward Robinson | Chief Scientific Officer | 2025-12-26 | 90,000 | $38.74 | $3.49MSell |
| Cole Pinnow | Chief Commercial Officer | 2025-12-17 | 94,800 | $39.45 | $3.74MSell |
| Andrew R. Robbins | President and CEO | 2025-12-17 | 367,497 | $39.45 | $14.50MSell |
| John Edward Robinson | Chief Scientific Officer | 2025-12-17 | 139,998 | $39.45 | $5.52MSell |
| John L. Green | Chief Financial Officer | 2025-12-17 | 145,007 | $39.45 | $5.72MSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Fmr LLC | 13.33% | 23,122,748 | $901.32M | Institution |
| Blackrock Inc | 9.25% | 16,045,014 | $625.43M | Institution |
| Deerfield Management Company LP | 5.21% | 9,043,903 | $352.53M | Institution |
| Vanguard Portfolio Management LLC | 4.23% | 7,333,333 | $285.85M | Institution |
| Vanguard Capital Management LLC | 3.97% | 6,894,959 | $268.77M | Institution |
| Janus Henderson Group PLC | 3.44% | 5,965,125 | $232.52M | Institution |
| State Street Corp | 3.26% | 5,663,543 | $220.76M | Institution |
| Fairmount Funds Management LLC | 3.17% | 5,503,418 | $214.52M | Institution |
| Fairmount Funds Management LLC | 3.17% | 5,503,418 | $214.52M | Insider |
| Rtw Investments LP | 3.15% | 5,458,675 | $212.78M | Institution |