| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Masaru Matsuda | Reporting Persons title EVP Chief Legal Officer | 2026-05-04 | 884 | $23.61 | $20.87kSell |
| Todd Watanabe | Reporting Persons title President and Chief Executive Officer | 2026-05-04 | 3,172 | $23.61 | $74.89kSell |
| Masaru Matsuda | Reporting Persons title EVP Chief Legal Officer | 2026-05-04 | 7,372 | $23.27 | $171.55kSell |
| Patrick Burnett | Reporting Persons Title EVP Chief Medical Officer | 2026-05-04 | 684 | $23.61 | $16.15kSell |
| Latha Vairavan | SVP Chief Financial Officer | 2026-05-04 | 1,341 | $23.61 | $31.66kSell |
| Howard G. Welgus | Director | 2026-05-01 | 7,144 | $22.99 | $164.22kSell |
| Howard G. Welgus | Director | 2026-04-01 | 10,000 | $23.88 | $238.80kSell |
| Masaru Matsuda | Reporting Persons title EVP Chief Legal Officer | 2026-03-02 | 193 | $25.91 | $5.00kSell |
| Latha Vairavan | SVP Chief Financial Officer | 2026-03-02 | 81 | $25.91 | $2.10kSell |
| Keith R. Leonard | Director | 2026-03-02 | 27,052 | $8.63 | $233.46kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Patrick J. Heron | 15.67% | 19,430,454 | $455.06M | Insider |
| Suvretta Capital Management LLC | 9.65% | 11,964,000 | $280.20M | Institution |
| Frazier Life Sciences Management LP | 7.96% | 9,874,511 | $231.26M | Institution |
| Blackrock Inc | 7.34% | 9,099,579 | $213.11M | Institution |
| Frazier Life Sciences VIII LP | 7.13% | 8,838,534 | $207.00M | Insider |
| Rubric Capital Management LP | 6.67% | 8,271,577 | $193.72M | Institution |
| Vanguard Group Inc | 5.85% | 7,253,936 | $169.89M | Institution |
| Jennison Associates LLC | 5.45% | 6,758,006 | $158.27M | Institution |
| Polar Capital Holdings PLC | 4.48% | 5,556,169 | $130.13M | Institution |
| State Street Corp | 4.42% | 5,488,301 | $128.54M | Institution |