| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Howard G. Welgus | Director | 2026-06-17 | 635 | $25.67 | $16.30kSell |
| Howard G. Welgus | Director | 2026-06-15 | 4,096 | $24.41 | $99.98kSell |
| Howard G. Welgus | Director | 2026-06-15 | 2,255 | $8.63 | $19.46kBuy |
| Suejean Lin | Director | 2026-06-15 | 4,946 | $24.38 | $120.59kSell |
| Howard G. Welgus | Director | 2026-06-15 | 1,019 | $7.51 | $7.65kBuy |
| Howard G. Welgus | Director | 2026-06-15 | 822 | $6.52 | $5.36kBuy |
| Patrick Burnett | Reporting Persons Title EVP Chief Medical Officer | 2026-05-11 | 222 | $21.05 | $4.67kSell |
| Latha Vairavan | SVP Chief Financial Officer | 2026-05-11 | 435 | $21.05 | $9.16kSell |
| Todd Watanabe | Reporting Persons title President and Chief Executive Officer | 2026-05-04 | 3,172 | $23.61 | $74.89kSell |
| Patrick Burnett | Reporting Persons Title EVP Chief Medical Officer | 2026-05-04 | 684 | $23.61 | $16.15kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Patrick J. Heron | 15.54% | 19,436,232 | $509.42M | Insider |
| Suvretta Capital Management LLC | 9.86% | 12,327,000 | $323.09M | Institution |
| Frazier Life Sciences Management LP | 7.89% | 9,874,511 | $258.81M | Institution |
| Blackrock Inc | 7.36% | 9,200,411 | $241.14M | Institution |
| Frazier Life Sciences VIII LP | 7.07% | 8,838,534 | $231.66M | Insider |
| Rubric Capital Management LP | 6.61% | 8,271,577 | $216.80M | Institution |
| State Street Corp | 5.03% | 6,296,197 | $165.02M | Institution |
| Polar Capital Holdings PLC | 4.53% | 5,666,940 | $148.53M | Institution |
| Jennison Associates LLC | 3.98% | 4,980,770 | $130.55M | Institution |
| Vanguard Capital Management LLC | 3.89% | 4,871,536 | $127.68M | Institution |