How to Buy Ionis Pharmaceuticals Stock
Ionis Pharmaceuticals Inc
Founded in 1989 and headquartered in Carlsbad, California, Ionis Pharmaceuticals, Inc. is a biopharmaceutical company specializing in the discovery and development of RNA-targeted therapies within the United States.
Ionis Pharmaceuticals stock last closed at $73.96, up 0.93% from the previous day, and has increased 109.88% in one year. It has overperformed other stocks in the Biotechnology industry by 1.82 percentage points. Ionis Pharmaceuticals stock is currently +104.82% from its 52-week low of $36.11, and -14.73% from its 52-week high of $86.74.
At the moment, there are 165.26M IONS shares outstanding. The market capitalization of IONS is $12.22B. In the past 24 hours, 1.51M IONS shares were traded.
How to Buy Ionis Pharmaceuticals Stock
Wondering how to invest in Ionis Pharmaceuticals stock? Here's how.
- Figure out where to buy Ionis Pharmaceuticals stock: You need to decide on an online brokerage, but don't worry - we've sifted through dozens of online stock brokerages and apps to help you determine where to buy Ionis Pharmaceuticals stock.
- Create a brokerage account: Sign up for 0% commission trading with the highest-rated brokerage we've identified.
- Fund your brokerage account: Choose your method of payment and add your details.
- Research Ionis Pharmaceuticals stock: The Ionis Pharmaceuticals ticker symbol is IONS. Is Ionis Pharmaceuticals stock a good investment? Should you buy shares of IONS? How do IONS's underlying business fundamentals look? Do top analysts think Ionis Pharmaceuticals is a good buy? Why has IONS's stock price moved recently? (Hint: Our stock market analysis website can help you figure out if IONS is a good stock to buy).
- Execute your IONS buy order: Decide if you will purchase IONS shares at the current market price or use a limit order to purchase IONS stock at a specific price.
- Get the latest news on your investment in IONS: Create a watchlist to the latest updates on your investment in Ionis Pharmaceuticals stock.
Step 1: Figure out where to buy Ionis Pharmaceuticals stock
You will need a brokerage account to access the NASDAQ market and buy IONS shares.
Our recommended brokerage: eToro
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Open eToro AccountStep 2: Create a brokerage account
Now that you've picked your brokerage, the next step is to fill out some personal information so you can invest in IONS today.
How to Set Up a New Brokerage Account on eToro
- Click here to get started.eToro is a multi-asset investment platform. The value of your investments may go up or down. Your capital is at risk.
- Input your personal data to open a new brokerage account.
- Submit your data by pressing the "Create Account" button. Get started with eToro today
Step 3: Fund your brokerage account
Now that you've filled out your info on the best stock app, your next step is to transfer the money for your investment:
Check out the walkthrough below to see the process of transferring money into your new brokerage account.
Step 4: Research Ionis Pharmaceuticals stock
Once you have decided on the best place to buy Ionis Pharmaceuticals stock, it's absolutely critical to evaluate their stock prior to investing, so you actually comprehend the risk and opportunity.
Ionis Pharmaceuticals quick stats
Ionis Pharmaceuticals Fundamentals
WallStreetZen was created to help average investors perform more accurate fundamental analysis quickly.
You can view all of the due diligence checks on IONS's stock page.
How is IONS stock valued?
You can use a variety of different financial metrics, analyses, models, and charts to gauge IONS's fair value.
Using relative valuations ratios:
- IONS could be overvalued based on its P/B ratio of 24.87x, relative to Biotechnology industry P/B ratio of 4.86x
You can access additional valuation research on IONS's stock here.
IONS Financials at a glance
Signs that IONS is financially healthy:
- There are more short-term assets than short-term liabilities on the IONS balance sheet.
- There are more short-term assets than long-term liabilities on the IONS balance sheet.
- IONS has cash burn of 971257000. It has sufficient cash and short-term investments to cover this for at least one year.
Signs that IONS is not financially healthy:
- IONS has $1.92B in cash and short term investments. This is not sufficient to cover its annual cash burn of $971.26M.
- IONS profit margin has gone up by 0.33 percentage points in the past year, but the company is still unprofitable.
- Total IONS debt is higher than 5 years ago, relative to shareholder equity.
- IONS has a relatively high debt to equity ratio of 6.02.
Do analysts think it's a good time to buy Ionis Pharmaceuticals stock
Out of 12 Equities analysts who track IONS, the consensus analyst rating on IONS is a Strong Buy
It's important to keep in mind that analyst ratings are not recommendations, nor are they financial advice.
Most Recent IONS Analyst Recommendations
Gary Nachman, a bottom 16% analyst from Canaccord Genuity initiates coverage on IONS with a strong buy rating and announces their IONS price target of $110.00, on Apr 21, 2026.
Michael Ulz, a top 8% analyst from Morgan Stanley maintains IONS with a strong buy rating and raises their IONS price target from $95.00 to $130.00, on Apr 21, 2026.
Morgan Stanley's Michael Ulz raised their price target on Ionis Pharmaceuticals (NASDAQ: IONS) by 36.8% from $95 to $130 on 2026/04/21. The analyst maintained their Strong Buy rating on the stock.
According to Ulz, RNA therapies have a promising future in treating severe hypertriglyceridemia, but this potential "remains underappreciated despite groundbreaking data and a high unmet need."
In spite of the $4.3B consensus estimate, the analyst raised their peak U.S. sales for severe hypertriglyceridemia estimates to $9B.
In addition, Ulz increased Ionis Pharmaceuticals' Tryngolza's peak sales estimate from $1.9B to $4.7B.
Jason Gerberry, a top 13% analyst from Bank of America maintains IONS with a strong buy rating and raises their IONS price target from $100.00 to $111.00, on Apr 9, 2026.
Joseph Stringer, a top 2% analyst from Needham maintains IONS with a buy rating and raises their IONS price target from $103.00 to $105.00, on Mar 25, 2026.
Mani Foroohar, a bottom 1% analyst from Leerink Partners maintains IONS with a buy rating and raises their IONS price target from $102.00 to $104.00, on Mar 3, 2026.
You can dive deeper into what analysts are forecasting on the Ionis Pharmaceuticals stock forecast page.
IONS Revenue
Last year, IONS revenue was $1.06B. Over the past 5 year, IONS's revenue has gone up by 8.38% per year. This was slower than the Biotechnology industry average of 32.16%.
You can analyze IONS's earnings and revenue performance here.
Latest Insiders Trades at IONS
In the past year, executives and large shareholders at IONS have sold more shares than they have bought.
Spencer R. Berthelsen, Director of IONS, was the latest IONS insider to buy. They bought $195,360.00 worth of IONS stock on Jun 15, 2026.
Dig into more about who owns IONS shares here.
Can I get consistent income from IONS stock?
No, Ionis Pharmaceuticals doesn't provide an income stream by paying out dividends.
IONS Social Trading Data
One of the primary reasons eToro is our favorite brokerage is because of its social trading community.
Click below to learn what other investors have to say.
Step 5: Execute your IONS buy order
You have two main order types:
- Market order: A market order is an order to buy or sell a security at the best possible price.
Market orders are usually sufficient. - Limit order: A limit order is an order to buy or sell a stock at a specific price (or better).
If you want to be certain you're buying or selling at a given dollar amount, place a limit order.
Hit the Open Trade button and eToro will place the order.
If you require additional assistance buying stocks on eToro, watch the helpful video below:
Step 6: Get the latest news on your investment in IONS
Now that you own some IONS shares, you'll want to stay up-to-date on your investment.
Start a watchlist to get alerted to the latest events about your IONS stock.
IONS Feed
How to Buy Stock in Ionis Pharmaceuticals
To reiterate, here are the 6 steps to buy Ionis Pharmaceuticals stock:
- Figure out where to buy Ionis Pharmaceuticals stock
- Create a brokerage account
- Fund your brokerage account
- Research Ionis Pharmaceuticals stock
- Execute your IONS buy order
- Get the latest news on your investment in IONS
If you need a online brokerage, eToro is our recommended option.
Get Started with eToro TodayIf you would like to get the latest news on your new investment in Ionis Pharmaceuticals, get started below.
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