| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Joseph Baroldi | EVP Chief Business Officer | 2026-06-26 | 3,866 | $56.78 | $219.51kBuy |
| Brett P. Monia | Chief Executive Officer | 2026-06-26 | 50,000 | $80.59 | $4.03MSell |
| Brett P. Monia | Chief Executive Officer | 2026-06-26 | 50,000 | $56.78 | $2.84MBuy |
| Patrick R. Oneil | EVP CLO General Counsel | 2026-06-26 | 3,069 | $80.00 | $245.52kSell |
| Eugene Schneider | EVP Chf Clinical Develop Ofcr | 2026-06-26 | 26,000 | $81.05 | $2.11MSell |
| Eugene Schneider | EVP Chf Clinical Develop Ofcr | 2026-06-26 | 26,000 | $60.89 | $1.58MBuy |
| Joseph Baroldi | EVP Chief Business Officer | 2026-06-26 | 5,635 | $80.16 | $451.70kSell |
| Joseph Baroldi | EVP Chief Business Officer | 2026-06-26 | 1,769 | $32.60 | $57.67kBuy |
| Eric Swayze | EVP Research | 2026-06-25 | 10,602 | $79.18 | $839.49kSell |
| Brett P. Monia | Chief Executive Officer | 2026-06-25 | 21,072 | $78.49 | $1.65MSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Fmr LLC | 14.86% | 24,556,637 | $1.88B | Institution |
| Capital World Investors | 12.82% | 21,186,369 | $1.62B | Institution |
| Blackrock Inc | 6.32% | 10,442,476 | $799.06M | Institution |
| Vanguard Portfolio Management LLC | 4.73% | 7,808,902 | $597.54M | Institution |
| Vanguard Capital Management LLC | 4.31% | 7,118,330 | $544.69M | Institution |
| Wellington Management Group LLP | 3.87% | 6,391,816 | $489.10M | Institution |
| T Rowe Price Investment Management Inc | 3.73% | 6,159,027 | $471.29M | Institution |
| Two Sigma Investments LP | 3.54% | 5,857,629 | $448.23M | Institution |
| State Street Corp | 2.42% | 3,995,564 | $305.74M | Institution |
| Geode Capital Management LLC | 2.41% | 3,984,332 | $304.88M | Institution |