| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Brett P. Monia | Chief Executive Officer | 2026-05-14 | 3,220 | $78.68 | $253.35kSell |
| Brett P. Monia | Chief Executive Officer | 2026-05-14 | 3,220 | $32.60 | $104.97kBuy |
| Brett P. Monia | Chief Executive Officer | 2026-05-13 | 1,316 | $32.60 | $42.90kBuy |
| Brett P. Monia | Chief Executive Officer | 2026-05-13 | 1,316 | $78.01 | $102.67kSell |
| Joseph Loscalzo | Director | 2026-05-04 | 17,781 | $75.58 | $1.34MSell |
| Joseph Loscalzo | Director | 2026-05-04 | 12,000 | $60.20 | $722.40kBuy |
| Joseph Loscalzo | Director | 2026-05-04 | 59,508 | $74.90 | $4.46MSell |
| Joseph Loscalzo | Director | 2026-05-04 | 16,000 | $42.88 | $686.08kBuy |
| Joseph Loscalzo | Director | 2026-05-04 | 10,321 | $41.08 | $423.99kBuy |
| Joseph Loscalzo | Director | 2026-05-04 | 12,000 | $40.05 | $480.60kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Vanguard Portfolio Management LLC | 4.73% | 7,808,902 | $589.18M | Institution |
| Vanguard Capital Management LLC | 4.31% | 7,118,330 | $537.08M | Institution |
| Lilly Co Eli | 1.51% | 2,500,000 | $188.63M | Insider |
| Tweedy Browne Co LLC 1 | 1.38% | 2,275,625 | $171.70M | Institution |
| Pictet Asset Management Holding Sa | 0.87% | 1,434,995 | $108.27M | Institution |
| Stanley T. Crooke | 0.80% | 1,324,914 | $99.96M | Insider |
| Invesco Ltd | 0.77% | 1,277,358 | $96.38M | Institution |
| Vanguard Fiduciary Trust Co | 0.62% | 1,024,377 | $77.29M | Institution |
| Connor Clark Lunn Investment Management Ltd | 0.53% | 874,089 | $65.95M | Institution |
| Ubs Group Ag | 0.49% | 808,443 | $61.00M | Institution |