| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Samarth Kulkarni | Chief Executive Officer | 2025-10-17 | 50,895 | $67.91 | $3.46MSell |
| Samarth Kulkarni | Chief Executive Officer | 2025-10-14 | 4,242 | $66.60 | $282.52kSell |
| James R. Kasinger | General Counsel and Secretary | 2025-10-14 | 1,076 | $66.60 | $71.66kSell |
| Samarth Kulkarni | Chief Executive Officer | 2025-08-18 | 13,081 | $58.15 | $760.66kSell |
| Douglas A. Treco | Director | 2025-08-06 | 20,000 | $57.03 | $1.14MBuy |
| Simeon George | Director | 2025-07-16 | 6,510 | $52.03 | $338.72kBuy |
| Simeon George | Director | 2025-07-16 | 960,983 | $52.03 | $50.00MBuy |
| Simeon George | Director | 2025-07-16 | 22,319 | $52.03 | $1.16MBuy |
| Naimish Patel | Chief Medical Officer | 2025-05-29 | 3,932 | $35.94 | $141.32kSell |
| Raju Prasad | Chief Financial Officer | 2025-03-21 | 2,197 | $41.23 | $90.58kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Ark Investment Management LLC | 11.20% | 10,182,590 | $622.16M | Institution |
| Celgene Corp | 9.41% | 8,557,514 | $522.86M | Insider |
| Blackrock Inc | 6.67% | 6,066,358 | $370.65M | Institution |
| Capital International Investors | 6.15% | 5,593,747 | $341.78M | Institution |
| Vertex Pharmaceuticals Europe Ltd | 5.92% | 5,380,940 | $328.78M | Insider |
| Simeon George | 5.78% | 5,259,390 | $321.35M | Insider |
| Bayer Global Investments Bv | 5.61% | 5,105,330 | $311.94M | Insider |
| T Rowe Price Investment Management Inc | 4.05% | 3,683,026 | $225.03M | Institution |
| State Street Corp | 3.60% | 3,270,596 | $199.83M | Institution |
| Glaxosmithkline PLC | 3.54% | 3,220,627 | $196.78M | Insider |