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NASDAQ: IONS
Ionis Pharmaceuticals Inc Stock Forecast, Predictions & Price Target

OverviewForecast
EarningsRevenueDividendOwnership

Analyst price target for IONS

Based on 19 analysts offering 12 month price targets for Ionis Pharmaceuticals Inc

Min Forecast
$46.00-37.06%
Avg Forecast
$77.47+6%
Max Forecast
$96.00+31.34%

Should I buy or sell IONS stock?

Based on 19 analysts offering ratings for Ionis Pharmaceuticals Inc.

Strong Buy
Strong Buy
10 analysts 52.63%
Buy
6 analysts 31.58%
Hold
3 analysts 15.79%
Sell
0 analysts 0%
Strong Sell
0 analysts 0%
Our proven Zen Rating quant model "Buy" agrees with analyst consensus with a "Strong Buy" rating. Learn More

Be the first to know when Wall Street analysts revise their IONS stock forecasts and price targets.

IONS stock forecasts by analyst

Analyst / FirmRatingActionPrice TargetUpside/DownsideDateAnalyst Color
lockedlocked$00.00+00.00%2025-10-16Find Out Why
lockedlocked$00.00+00.00%2025-10-08
lockedlocked$00.00+00.00%2025-10-08
lockedlocked$00.00+00.00%2025-10-08Find Out Why
lockedlocked$00.00+00.00%2025-10-08
Stifel Nicolaus
Bottom 13%
13
HoldMaintains$67.00-8.33%2025-10-06
Goldman Sachs
Top 23%
78
HoldUpgrades$65.00-11.07%2025-09-26
Guggenheim
Top 8%
93
Strong BuyMaintains$92.00+25.87%2025-09-23Find out why
Bank of America
Top 25%
76
Strong BuyMaintains$83.00+13.56%2025-09-23
Barclays
Top 26%
75
Strong BuyMaintains$80.00+9.45%2025-09-23

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Forecast return on equity

Is IONS forecast to generate an efficient return?

Company
4.95%
Industry
96.93%
Market
-62.31%
IONS's Return on Equity is... subscribe to Premium to read more.
Forecast High Return on Equity Forecast

Forecast return on assets

Is IONS forecast to generate an efficient return on assets?

Company
1.05%
Industry
35.83%
IONS is forecast to generate... subscribe to Premium to read more.
Forecast Return on Assets vs Industry Forecast

IONS earnings per share forecast

What is IONS's earnings per share in the next 3 years based on estimates from 12 analysts?

Avg 1 year Forecast
-$2.65
Avg 2 year Forecast
-$3.54
Avg 3 year Forecast
-$1.74

IONS revenue forecast

What is IONS's revenue in the next 3 years based on estimates from 9 analysts?

Avg 1 year Forecast
$857.4M-9.18%
Avg 2 year Forecast
$839.4M-11.09%
Avg 3 year Forecast
$1.2B+31.34%
IONS's revenue is forecast to... subscribe to Premium to read more.
Forecast High Revenue Growth Forecast

IONS revenue growth forecast

How is IONS forecast to perform vs Biotechnology companies and vs the US market?

Company
7.2%
Industry
90.96%
Market
11.86%
IONS's revenues are forecast to... subscribe to Premium to read more.
Forecast Revenue Growth vs Industry Forecast
IONS's revenues are forecast to... subscribe to Premium to read more.
Forecast Revenue Growth vs Market Forecast

IONS vs Biotech Stocks

TickerPricePrice TargetUp/downsideConsensus
IONS$73.09$77.47+6.00%Strong Buy
ROIV$17.26$19.94+15.52%Strong Buy
EXEL$39.25$46.31+17.99%Buy
ASND$210.50$258.50+22.80%Strong Buy
BBIO$54.92$68.08+23.96%Strong Buy
View Top Biotech Stocks

Ionis Pharmaceuticals Stock Forecast FAQ

Is Ionis Pharmaceuticals Stock a good buy in 2025, according to Wall Street analysts?

The consensus among 19 Wall Street analysts covering (NASDAQ: IONS) stock is to Strong Buy IONS stock.

Out of 19 analysts, 10 (52.63%) are recommending IONS as a Strong Buy, 6 (31.58%) are recommending IONS as a Buy, 3 (15.79%) are recommending IONS as a Hold, 0 (0%) are recommending IONS as a Sell, and 0 (0%) are recommending IONS as a Strong Sell.

If you're new to stock investing, here's how to buy Ionis Pharmaceuticals stock.

What is IONS's earnings growth forecast for 2025-2027?

(NASDAQ: IONS) Ionis Pharmaceuticals's forecast annual earnings growth rate of N/A is not forecast to beat the US Biotechnology industry's average forecast earnings growth rate of 4.13%, and while it is not forecast to beat the US market's average forecast earnings growth rate of 16.01%.

Ionis Pharmaceuticals's earnings in 2025 is -$268,216,000.On average, 12 Wall Street analysts forecast IONS's earnings for 2025 to be -$421,717,314, with the lowest IONS earnings forecast at -$519,615,407, and the highest IONS earnings forecast at -$226,335,545. On average, 12 Wall Street analysts forecast IONS's earnings for 2026 to be -$563,447,995, with the lowest IONS earnings forecast at -$749,138,776, and the highest IONS earnings forecast at -$321,970,283.

In 2027, IONS is forecast to generate -$277,340,738 in earnings, with the lowest earnings forecast at -$508,458,021 and the highest earnings forecast at -$22,314,772.

What is IONS's revenue growth forecast for 2025-2027?

(NASDAQ: IONS) Ionis Pharmaceuticals's forecast annual revenue growth rate of 7.2% is not forecast to beat the US Biotechnology industry's average forecast revenue growth rate of 90.96%, and while it is not forecast to beat the US market's average forecast revenue growth rate of 11.86%.

Ionis Pharmaceuticals's revenue in 2025 is $944,051,000.On average, 9 Wall Street analysts forecast IONS's revenue for 2025 to be $136,666,183,917, with the lowest IONS revenue forecast at $132,737,827,687, and the highest IONS revenue forecast at $151,804,206,500. On average, 9 Wall Street analysts forecast IONS's revenue for 2026 to be $133,785,506,235, with the lowest IONS revenue forecast at $108,629,904,300, and the highest IONS revenue forecast at $160,347,576,374.

In 2027, IONS is forecast to generate $197,633,647,792 in revenue, with the lowest revenue forecast at $145,360,019,111 and the highest revenue forecast at $228,726,413,615.

What is IONS's forecast return on assets (ROA) for 2025-2028?

(NASDAQ: IONS) forecast ROA is 1.05%, which is lower than the forecast US Biotechnology industry average of 35.83%.

What is IONS's Price Target?

According to 19 Wall Street analysts that have issued a 1 year IONS price target, the average IONS price target is $77.47, with the highest IONS stock price forecast at $96.00 and the lowest IONS stock price forecast at $46.00.

On average, Wall Street analysts predict that Ionis Pharmaceuticals's share price could reach $77.47 by Oct 16, 2026. The average Ionis Pharmaceuticals stock price prediction forecasts a potential upside of 6% from the current IONS share price of $73.09.

What is IONS's Earnings Per Share (EPS) forecast for 2025-2027?

(NASDAQ: IONS) Ionis Pharmaceuticals's current Earnings Per Share (EPS) is -$1.76. On average, analysts forecast that IONS's EPS will be -$2.65 for 2025, with the lowest EPS forecast at -$3.26, and the highest EPS forecast at -$1.42. On average, analysts forecast that IONS's EPS will be -$3.54 for 2026, with the lowest EPS forecast at -$4.70, and the highest EPS forecast at -$2.02. In 2027, IONS's EPS is forecast to hit -$1.74 (min: -$3.19, max: -$0.14).

What is IONS's forecast return on equity (ROE) for 2025-2028?

(NASDAQ: IONS) forecast ROE is 4.95%, which is considered weak.
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