Spruce Biosciences, Inc. , founded in 2014 and situated in Daly City, California, operates as a biopharmaceutical enterprise.
Spruce Biosciences stock last closed at $52.36, up 7.38% from the previous day, and has increased 872.33% in one year. It has overperformed other stocks in the Biotechnology industry by 9.44 percentage points. Spruce Biosciences stock is currently +997.69% from its 52-week low of $4.77, and -78.18% from its 52-week high of $240.00.
At the moment, there are 2.75M shares of SPRB outstanding. The market value of SPRB is $144.11M. In the last 24 hours, 139,000 SPRB shares were traded.
How to Buy Spruce Biosciences Stock
Not sure how to invest in Spruce Biosciences stock? Here's how.
Choose where to buy Spruce Biosciences stock: You need to choose a stock brokerage, but don't worry - we've tested dozens of online stock brokerages and apps to help you figure out where to buy Spruce Biosciences stock.
Sign up for your brokerage account: Sign up for 0% commission trading with the highest-rated brokerage we've identified.
Fund your brokerage account: Pick your method of payment and add your details.
Evaluate Spruce Biosciences stock: The Spruce Biosciences ticker symbol is SPRB. Is Spruce Biosciences stock a good investment? Should you buy shares of SPRB? How do SPRB's underlying business fundamentals look? Do top analysts think Spruce Biosciences is a good buy? Why has SPRB's stock price moved recently? (Hint: Our stock market analysis tools can help you figure out if SPRB is a good stock to buy).
Make your SPRB buy order: Decide if you will purchase SPRB shares at the current market price or use a limit order to buy SPRB shares at a given price.
Get the latest news on your investment in SPRB: Create a watchlist to track your position in Spruce Biosciences stock.
Step 1: Choose where to buy Spruce Biosciences stock
You will need an online brokerage account to access the NASDAQ market and buy SPRB shares.
A brokerage account allows you to buy and sell a number of investments, such as stocks, bonds, mutual funds, and ETFs.
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Step 2: Sign up for your brokerage account
Now that you've chosen the best brokerage, it's time to fill out some personal info so you are able to buy SPRB today.
eToro is a multi-asset investment platform. The value of your investments may go up or down. Your capital is at risk.
Step 4: Evaluate Spruce Biosciences stock
Once you have selected the best place to buy Spruce Biosciences stock, it's crucial to evaluate their stock prior to investing, so you truly understand the risk as well as the upside.
Spruce Biosciences shares data
SPRB Price
$52.36
1w %
6.63%
1y %
872.33%
5y %
-93.96%
P/E
-1.43x
P/B
4.16x
P/S
N/A
PEG
N/A
Revenue
$0.00
Earnings
-$37.19M
Fore. Rev. Growth
N/A
Fore. Earn. Growth
N/A
Market Cap
$144.11M
Next Earnings
N/A
Next Dividend
N/A
Spruce Biosciences Due Diligence Score
WallStreetZen was designed to help everyday investors perform more in-depth fundamental analysis.
SPRB has $54.08M in cash and short term investments. This is sufficient to cover its annual cash burn of $29.34M.
There are more short-term assets than long-term liabilities on the SPRB balance sheet.
SPRB has cash burn of 29342000. It has enough cash and short-term investments to cover this for at least one year.
There are more short-term assets than short-term liabilities on the SPRB balance sheet.
Signs that SPRB is not financially healthy:
Total SPRB debt is higher than 5 years ago, relative to shareholder equity.
SPRB has a relatively high debt to equity ratio of 0.62.
Do analysts think it's a good time to buy SPRB stock
Out of 6 Wall Street analysts who monitor SPRB, the consensus analyst rating on SPRB is a Strong Buy
It's important to note that analyst ratings are not stock recommendations, nor are they investment advice.
Latest SPRB Analyst Forecasts
Leland Gershell, a top 4% analyst from Oppenheimer initiates coverage on SPRB with a buy rating and announces their SPRB price target of $283.00, on Dec 23, 2025.
Last year, SPRB revenue was $0.00. Over the past three year, SPRB's revenue has gone up by -100% per year. This was slower than the Biotechnology industry average of 32.37%.
No, Spruce Biosciences doesn't provide an income stream by paying out dividends.
SPRB Social Trading Data
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Step 5: Make your SPRB buy order
There are two main options:
Market order: A market order is an order to buy or sell a stock at the best possible price. Market orders are mostly fine.
Limit order: A limit order enables you to buy or sell a security at a specific price (or better). If you want to be sure you're buying or selling at a particular dollar amount, place a limit order.
Click the Open button and eToro will place your order.
If you need more help with buying stocks on eToro, watch the how to video below:
How much does it cost to buy one Spruce Biosciences share?
As of Jun 18, 2026, it costs $52.36 to buy one share of Spruce Biosciences stock.
Remember, eToro's fractional share buying allows you to buy partial shares of stocks and ETFs. Even if you only have $10, you can buy 0.191 shares of SPRB.
WallStreetZen does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.
Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.