How to Buy Spero Therapeutics Stock

Spero Therapeutics Inc

Spero Therapeutics, Inc. , a clinical-stage biopharmaceutical company, focuses on identifying, developing, and commercializing treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States.

Spero Therapeutics stock last closed at $1.98, down 3.54% from the previous day, and has increased 57.85% in one year. It has overperformed other stocks in the Biotechnology industry by 1.22 percentage points. Spero Therapeutics stock is currently +292.08% from its 52-week low of $0.51, and -38.51% from its 52-week high of $3.22.

As of Aug 14, 2025, there are 56.28M SPRO shares outstanding. The market value of SPRO is $111.42M. In the last 24 hours, 626,000 SPRO shares were traded.

How to Buy Spero Therapeutics Stock

Not sure how to invest in Spero Therapeutics stock? Here's how.

  1. Decide where to buy Spero Therapeutics stock: You need to choose an online brokerage, but don't worry - we've analyzed dozens of stock brokerages and apps to help you determine where to buy Spero Therapeutics stock.
  2. Create your brokerage account: Sign up for 0% fee trading with the highest-rated brokerage we've found.
  3. Deposit funds into your brokerage account: Choose your method of payment and add your details.
  4. Research Spero Therapeutics stock: The Spero Therapeutics ticker symbol is SPRO. Is Spero Therapeutics stock a good investment? Should you buy shares of SPRO? How do SPRO's underlying business fundamentals look? Do top analysts think Spero Therapeutics is a good buy? Why has SPRO's stock price moved recently? (Hint: Our stock analysis website can help you understand if SPRO is a good stock to buy).
  5. Execute your SPRO trade: Decide if you will purchase SPRO shares at the current market price or use a limit order to purchase SPRO stock at a particular price.
  6. Get the latest scoop on your investment in SPRO: Create a watchlist to monitor your new investment in Spero Therapeutics shares.

Step 1: Decide where to buy Spero Therapeutics stock

You need an online brokerage account in order to access the NASDAQ market and buy SPRO shares.

A brokerage account is an investment account that enables you to buy and sell a number of financial instruments, such as stocks, bonds, mutual funds, and ETFs.

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Step 2: Create your brokerage account

Now that you've chosen your brokerage, you need to fill out some personal info so you can invest in SPRO stock today.

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  1. Send your information by pressing the "Create Account" button.
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Step 3: Deposit funds into your brokerage account

Now that you've finished signing up on one of the best stock trading apps, you need to deposit funds:

Check out the tutorial below to see the process of depositing money into your new investment account.

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Step 4: Research Spero Therapeutics stock

After you have chosen the best place to buy Spero Therapeutics stock, it's absolutely critical to research their stock prior to buying, so you can comprehend the risk and upside.

Spero Therapeutics quick stats

SPRO Price
$1.98
1w %
-12.79%
1y %
57.85%
5y %
-85.53%
P/E
-2.02x
P/B
3.39x
P/S
2.28x
PEG
N/A
Revenue
$48.58M
Earnings
-$53.60M
Fore. Rev. Growth
23.52%
Fore. Earn. Growth
N/A
Market Cap
$111.42M
Next Earnings
N/A
Next Dividend
N/A

Spero Therapeutics Due Diligence Checks

WallStreetZen was designed to help average investors perform more in-depth fundamental analysis in less time.

You can view all of the due diligence checks on SPRO's stock page.

Is SPRO stock properly valued?

Analysts use many financial metrics, analyses, models, and charts to gauge SPRO's true value.

Using relative valuations ratios:

  • SPRO may be undervalued based on its P/B ratio of 3.39x, relative to Biotechnology industry P/B ratio of 4.42x

You can access additional valuation analysis on SPRO's stock here.

SPRO Financials at a glance

Positive Financial Indicators:

  • There are more short-term assets than long-term liabilities on the SPRO balance sheet.
  • SPRO has $31.19M in cash and short term investments. This is enough to cover its annual cash burn of $32.33M.
  • There are more short-term assets than short-term liabilities on the SPRO balance sheet.

Negative Financial Indicators:

  • SPRO has a relatively high debt to equity ratio of 0.89.
  • SPRO has cash burn of 32333000. It does not have enough cash and short-term investments to cover this.
  • Total SPRO debt is higher than 5 years ago, relative to shareholder equity.
  • SPRO profit margin has gone down from 14.7% to -110.3% in the past year.

You can dive deeper into what analysts are forecasting on the Spero Therapeutics stock forecast page.

SPRO Momentum

SMA10
2.14
SMA20
2.22
SMA50
2.57
SMA100
1.73
SMA200
1.36
MACD
-0.13
MACD Signal
-0.1
MACD Histogram
-0.03
RSI
35.04
Stochastic %K
8.39
Stochastic %D
24.82
StochRSI %K
17.62
StochRSI %D
43.01

SPRO Performance Metrics

Last year, SPRO revenue was $48.58M. In the last five year, SPRO's revenue has grown by 32.94% per year. This was slower than the Biotechnology industry average of 63.37%.

Learn more about SPRO's earnings and revenue performance here.

Who is buying/selling SPRO?

Over the past 12 months, insiders at SPRO have sold more shares than they have bought.

Timothy Keutzer, Chief Operating Officer of SPRO, was the latest SPRO insider to sell. They sold $3,099.72 worth of SPRO stock on Feb 5, 2025.

Learn more about who owns SPRO shares here.

Does SPRO stock generate passive income?

No, Spero Therapeutics doesn't provide an income stream by paying out dividends.

What do other investors have to say about SPRO?

One of the primary reasons eToro is our highest-rated brokerage is because of its social trading community.

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Step 5: Execute your SPRO trade

There are two main types of orders:

  • Market order: A market order is an order to buy or sell a stock at the best possible price.
    Market orders are generally the easiest way to buy.
  • Limit order: A limit order enables you to buy or sell a stock at a specific price (or better).
    If you want to ensure you're buying or selling at a specific price, place a limit order.

Press the Open button and your broker will place your order.

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Step 6: Get the latest scoop on your investment in SPRO

Now that you own some SPRO stock, you'll want to stay up-to-date on your company.

Add SPRO to a watchlist to get alerted to the latest events about your SPRO stock.

SPRO Feed

How to Buy Stock in Spero Therapeutics

To summarize, here are the 6 steps you need to take to buy Spero Therapeutics stock right now:

  1. Decide where to buy Spero Therapeutics stock
  2. Create your brokerage account
  3. Deposit funds into your brokerage account
  4. Research Spero Therapeutics stock
  5. Execute your SPRO trade
  6. Get the latest scoop on your investment in SPRO

If you are looking for a brokerage account, eToro is our recommended venue.

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If you want to get the latest scoop on your investment in Spero Therapeutics, click below.

NASDAQ: SPRO
$1.98+0.00 (+0%)
Updated Aug 14, 2025
Open eToro Account
Your capital is at risk.
NASDAQ: SPRO
$1.98+0.00 (+0%)
Updated Aug 14, 2025
Open eToro Account
Your capital is at risk.

FAQ

How much does it cost to buy one Spero Therapeutics share?

As of Aug 14, 2025, it costs $1.98 to buy one share of Spero Therapeutics stock.

Remember, eToro's fractional share buying allows you to buy partial shares of stocks and ETFs. Even if you only have $0.99, you can buy 0.5 shares of SPRO.

Get Started with eToro Today
eToro is a multi-asset investment platform. The value of your investments may go up or down. Your capital is at risk.

What is the best way to buy Spero Therapeutics stock?

One way to place an order for Spero Therapeutics stock is with a brokerage account.
WallStreetZen does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.

Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.