How to Buy Spero Therapeutics Stock

Spero Therapeutics Inc

Spero Therapeutics, Inc. is a biopharmaceutical firm in the clinical development stage, primarily focused on discovering, advancing, and commercializing innovative treatments for multi-drug resistant (MDR) bacterial infections and rare diseases within the United States.

Spero Therapeutics stock last closed at $1.14, up 0.88% from the previous day, and has decreased 39.36% in one year. It has underperformed other stocks in the Biotechnology industry by 0.25 percentage points. Spero Therapeutics stock is currently +5.56% from its 52-week low of $1.08, and -62.99% from its 52-week high of $3.08.

As of Sep 14, 2026, there are 58.23M SPRO shares outstanding. The market value of SPRO is $66.39M. In the past 24 hours, 266,000 SPRO shares were traded.

How to Buy Spero Therapeutics Stock

Wondering how to invest in Spero Therapeutics stock? Here's how.

  1. Decide where to buy Spero Therapeutics stock: You need to decide on an online brokerage, but don't worry - we've tried dozens of stock brokerages and apps to help you decide where to buy Spero Therapeutics stock.
  2. Create your brokerage account: Sign up for 0% fee trading with the highest-rated brokerage we've identified.
  3. Deposit funds into your brokerage account: Choose your payment method and add your info.
  4. Research Spero Therapeutics stock: The Spero Therapeutics ticker symbol is SPRO. Is Spero Therapeutics stock a good investment? Should you buy shares of SPRO? How do SPRO's underlying business fundamentals look? Do top analysts think Spero Therapeutics is a good buy? Why has SPRO's stock price moved recently? (Hint: Our stock research tools can help you figure out if SPRO is a good stock to buy).
  5. Execute your SPRO trade: Decide if you will purchase SPRO shares at the current market price or use a limit order to buy SPRO stock at a specific price.
  6. Get the latest scoop on your investment in SPRO: Create a watchlist to key updates about your new investment in Spero Therapeutics stock.

Step 1: Decide where to buy Spero Therapeutics stock

You will need a brokerage account in order to access the NASDAQ market and buy SPRO shares.

A brokerage account allows you to buy and sell a number of financial instruments, including stocks, bonds, mutual funds, and ETFs.

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Step 2: Create your brokerage account

Now that you've selected your brokerage, it's time to fill out some personal details so you are able to buy SPRO stock today.

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Step 3: Deposit funds into your brokerage account

Now that you've created your account on the best stock trading app for beginners, you can securely and quickly fund your account:

Check out the walkthrough below to see the process of depositing money into your brokerage account.

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Step 4: Research Spero Therapeutics stock

After you have decided on the best place to buy Spero Therapeutics stock, it's crucial to evaluate their stock before you invest, so you actually understand the risk as well as the upside.

Spero Therapeutics shares at a glance

SPRO Price
$1.14
1w %
-4.2%
1y %
-39.36%
5y %
-93.85%
P/E
8.14x
P/B
1.5x
P/S
1.41x
PEG
0.06x
Revenue
$47.00M
Earnings
$7.38M
Fore. Rev. Growth
-14.78%
Fore. Earn. Growth
128.15%
Market Cap
$66.39M
Next Earnings
N/A
Next Dividend
N/A

SPRO Due Diligence Checks

WallStreetZen was built to help everyday investors perform more accurate fundamental analysis quickly.

You can view all of the due diligence checks on SPRO's stock page.

Is SPRO stock properly valued?

Analysts use many financial metrics, analyses, models, and charts to gauge SPRO's fair value.

Using relative valuations methods:

  • SPRO could be undervalued based on its P/E ratio of 8.14x, relative to Biotechnology industry P/E ratio of 8.25x
  • SPRO may be undervalued based on its P/B ratio of 1.5x, relative to Biotechnology industry P/B ratio of 5.35x
  • SPRO could be undervalued based on its PEG ratio of 0.06x

You can access additional valuation analysis on SPRO's stock here.

SPRO Financial Summary

Positive Financial Indicators:

  • SPRO earnings of $7.64M is not enough to cover its interest payments.
  • Total SPRO debt is lower than 5 years ago, relative to shareholder equity.
  • SPRO has a low debt to equity ratio of 0.19.
  • SPRO's operating cash flow of $19.58M allows it to safely service it's debt of $2.04M.
  • There are more short-term assets than long-term liabilities on the SPRO balance sheet.
  • There are more short-term assets than short-term liabilities on the SPRO balance sheet.
  • SPRO profit margin has gone up from -110.3% to 15.7% in the past year.

Is it a good time to buy SPRO stock, according to Wall Street analysts?

Out of 1 Wall Street analysts who monitor SPRO, the consensus analyst rating on SPRO is a Buy

It's important to keep in mind that analyst forecasts are not stock recommendations, nor are they investment advice.

You can dig deeper into what analysts are forecasting on the Spero Therapeutics stock forecast page.

SPRO Technical Indicators

SMA10
1.18
SMA20
1.2
SMA50
1.36
SMA100
1.97
SMA200
2.19
MACD
-0.06
MACD Signal
-0.07
MACD Histogram
0.01
RSI
33.12
Stochastic %K
7.14
Stochastic %D
4.41
StochRSI %K
20.33
StochRSI %D
12.71

SPRO Performance Metrics

Last year, SPRO earnings were $7.38M. In the last 3 year, SPRO's earnings have gone up by 55.03% per year. This was faster than the Biotechnology industry average of 9.68%.

Last year, SPRO revenue was $47.00M. Over the past five year, SPRO's revenue has increased by 20.69% per year. This was slower than the Biotechnology industry average of 24.04%.

You can research SPRO's earnings and revenue performance here.

What are SPRO executives and large shareholders up to?

Over the past year, executives and large shareholders at SPRO have sold more shares than they have bought.

Esther Rajavelu, Chief Executive Officer Chief Financial Officer and Chief Business Officer of SPRO, was the latest SPRO insider to sell. They sold $63,352.40 worth of SPRO stock on May 4, 2026.

Get more info about who owns SPRO shares here.

Can I rely on SPRO as an income stream?

No, Spero Therapeutics doesn't provide an income stream by paying out dividends.

What do other traders have to say about SPRO?

One of the primary reasons eToro is our top-rated brokerage is because of its social trading community.

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Step 5: Execute your SPRO trade

There are two main types of orders:

  • Market order: A market order is an order to buy or sell a security at the best possible price.
    Market orders are generally the best for newer investors.
  • Limit order: A limit order allows you to buy or sell a security at a specific price (or better).
    If you want to be certain you're buying or selling at a particular price, use a limit order.

Click the Open button and eToro will execute the order.

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Step 6: Get the latest scoop on your investment in SPRO

Now that you own some SPRO shares, you'll want to keep up with your new company.

Add SPRO to a watchlist to get alerted to the latest events about your SPRO stock.

SPRO Feed

How to Buy Stock in Spero Therapeutics

To reiterate, here are the 6 steps for buying Spero Therapeutics stock:

  1. Decide where to buy Spero Therapeutics stock
  2. Create your brokerage account
  3. Deposit funds into your brokerage account
  4. Research Spero Therapeutics stock
  5. Execute your SPRO trade
  6. Get the latest scoop on your investment in SPRO

If you need a online brokerage, eToro is our favorite option.

Get Started with eToro Today
eToro is a multi-asset investment platform. The value of your investments may go up or down. Your capital is at risk.

If you would like to get the latest news on your new investment in Spero Therapeutics, add SPRO to your watchlist below.

NASDAQ: SPRO
$1.14+0.01 (+0.88%)
Updated Sep 14, 2026
Open eToro Account
Your capital is at risk.
NASDAQ: SPRO
$1.14+0.01 (+0.88%)
Updated Sep 14, 2026
Open eToro Account
Your capital is at risk.

FAQ

How much does it cost to buy one Spero Therapeutics share?

As of Sep 14, 2026, it costs $1.14 to buy one share of Spero Therapeutics stock.

Remember, eToro's fractional share buying allows you to buy partial shares of stocks and ETFs. Even if you only have $0.57, you can buy 0.5 shares of SPRO.

Get Started with eToro Today
eToro is a multi-asset investment platform. The value of your investments may go up or down. Your capital is at risk.

Is now a good time to buy Spero Therapeutics stock?

According to 1 Wall Street analysts who monitor Spero Therapeutics, their consensus recommendation is to buy Spero Therapeutics stock.

What is the best way to buy Spero Therapeutics stock?

One way to place an order for Spero Therapeutics stock is with a brokerage account.
WallStreetZen does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.

Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.