How to Buy Protagonist Therapeutics Stock

Protagonist Therapeutics Inc

Protagonist Therapeutics, Inc. , a biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address hematology and blood disorders, and inflammatory and immunomodulatory diseases.

Protagonist Therapeutics stock last closed at $101.68, up 4.73% from the previous day, and has increased 87.08% in one year. It has overperformed other stocks in the Biotechnology industry by 1.32 percentage points. Protagonist Therapeutics stock is currently +156.77% from its 52-week low of $39.60, and -3.79% from its 52-week high of $105.69.

There are currently 63.81M PTGX shares outstanding. The market value of PTGX is $6.49B. In the last 24 hours, 1.92M PTGX shares were traded.

How to Buy Protagonist Therapeutics Stock

Not sure how to invest in Protagonist Therapeutics stock? Here's how.

  1. Figure out where to buy Protagonist Therapeutics stock: You need to pick a stock brokerage, but don't worry - we've sifted through dozens of online stock brokerages and apps to help you decide where to buy Protagonist Therapeutics stock.
  2. Open your brokerage account: Sign up for 0% fee trading with the highest-rated brokerage we've identified.
  3. Put funds into your investment account: Select your method of payment and add your info.
  4. Analyze Protagonist Therapeutics stock: The Protagonist Therapeutics ticker symbol is PTGX. Is Protagonist Therapeutics stock a good investment? Should you buy shares of PTGX? How do PTGX's underlying business fundamentals look? Do top analysts think Protagonist Therapeutics is a good buy? Why has PTGX's stock price moved recently? (Hint: Our stock market analysis tools can help you evaluate if PTGX is a good stock to buy).
  5. Make your PTGX buy order: Decide if you will purchase PTGX shares at the current market price or use a limit order to purchase PTGX stock at a given price.
  6. Keep an eye on your PTGX investment: Create a watchlist to monitor your investment in Protagonist Therapeutics stock.

Step 1: Figure out where to buy Protagonist Therapeutics stock

You will need an online brokerage account to access the NASDAQ market and buy PTGX stock.

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Step 2: Open your brokerage account

Now that you've selected the best brokerage, you'll need to fill out some personal details so you can invest in PTGX stock today.

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Step 3: Put funds into your investment account

Now that you've finished signing up on investing apps, you can securely and quickly fund your account:

Watch the video below for more details depositing money into your new brokerage account.

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Step 4: Analyze Protagonist Therapeutics stock

After you have selected the best place to buy Protagonist Therapeutics stock, it's absolutely critical to research their stock prior to investing, so you truly wrap your head around the risk as well as the opportunity.

Protagonist Therapeutics stock data

PTGX Price
$101.68
1w %
6.56%
1y %
87.08%
5y %
226.42%
P/E
-49.6x
P/B
10.55x
P/S
140.44x
PEG
N/A
Revenue
$46.02M
Earnings
-$130.15M
Fore. Rev. Growth
70.67%
Fore. Earn. Growth
N/A
Market Cap
$6.49B
Next Earnings
May 6, 2026
Next Dividend
N/A

Fundamentals of Protagonist Therapeutics

WallStreetZen was built to help average investors do more accurate fundamental analysis quickly.

You can view all of the due diligence checks on PTGX's stock page.

Is PTGX stock undervalued?

Analysts use many financial metrics, analyses, models, and charts to gauge PTGX's fair value.

Using relative valuations metrics:

  • PTGX could be overvalued based on its P/B ratio of 10.55x, relative to Biotechnology industry P/B ratio of 4.68x

You can access more valuation research on PTGX's stock here.

PTGX Financial Overview

Signs that PTGX is financially healthy:

  • PTGX's operating cash flow of $57.67M allows it to safely service it's debt of $10.32M.
  • There are more short-term assets than short-term liabilities on the PTGX balance sheet.
  • There are more short-term assets than long-term liabilities on the PTGX balance sheet.
  • PTGX has a low debt to equity ratio of 0.09.
  • Total PTGX debt is lower than 5 years ago, relative to shareholder equity.

Signs that PTGX is not financially healthy:

  • PTGX earnings of -$129.31M is not enough to cover its interest payments.
  • PTGX profit margin has gone down from 63.3% to -282.8% in the past year.

Is it a good time to buy Protagonist Therapeutics stock, according to Wall Street analysts?

Out of 12 Equities analysts who monitor PTGX, the consensus analyst rating on Protagonist Therapeutics is a Strong Buy

Please note that analyst ratings are not stock recommendations, nor are they investment advice.

Most Recent PTGX Analyst Upgrades/Downgrades

Tara Bancroft, a top 33% analyst from TD Cowen maintains PTGX with a strong buy rating and raises their PTGX price target from $90.00 to $100.00, on Feb 26, 2026.

Jonathan Wolleben, a top 3% analyst from Citizens maintains PTGX with a buy rating and raises their PTGX price target from $102.00 to $112.00, on Feb 26, 2026.

Roger Song, a top 19% analyst from Jefferies maintains PTGX with a strong buy rating and raises their PTGX price target from $95.00 to $118.00, on Feb 2, 2026.

Douglas Tsao, a top 2% analyst from HC Wainwright & Co. maintains PTGX with a buy rating and raises their PTGX price target from $80.00 to $117.00, on Jan 30, 2026.

Srikripa Devarakonda, a top 12% analyst from Truist Securities maintains PTGX with a strong buy rating and raises their PTGX price target from $88.00 to $110.00, on Jan 5, 2026.

Truist Securities's Srikripa Devarakonda raised their price target on Protagonist Therapeutics (NASDAQ: PTGX) by 25% from $88 to $110 on 2026/01/05. The analyst maintained their Strong Buy rating on the stock.

Contextualizing their price target hike on Protagonist Therapeutics, Devarakonda predicted that 2026 will be a key year for the company because:

  • Rusfertide is expected to be under regulatory review.
  • ICO approval in PsO expected.
  • Upside to the stock price from pipeline progress is possible.

You can dig deeper into what analysts are projecting on the Protagonist Therapeutics stock forecast page.

PTGX Technicals

SMA10
96.28
SMA20
92.95
SMA50
86.78
SMA100
86.02
SMA200
72.52
MACD
3.46
MACD Signal
2.97
MACD Histogram
0.49
RSI
68.96
Stochastic %K
80.96
Stochastic %D
80.16
StochRSI %K
55.85
StochRSI %D
42.55

How are PTGX Revenues/Earnings doing?

Last year, PTGX revenue was $46.02M. Over the past 5 year, PTGX's revenue has increased by 9.96% per year. This was slower than the Biotechnology industry average of 29.02%.

Dig into PTGX's earnings and revenue performance here.

Are PTGX executives and large shareholders buying or selling the stock?

In the past 12 months, insiders at PTGX have sold more shares than they have bought.

Lewis T. Williams, Director of PTGX, was the latest PTGX insider to buy. They bought $195,120.00 worth of PTGX stock on Feb 17, 2026.

Dig into more about who owns PTGX stock here.

Does PTGX stock generate passive income?

No, Protagonist Therapeutics doesn't provide an income stream by paying out dividends.

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Step 5: Make your PTGX buy order

There are two primary types of orders:

  • Market order: A market order is an order to buy or sell a security at the best price on the market.
    Market orders are usually sufficient.
  • Limit order: A limit order is an order to buy or sell a security at a specific price (or better).
    If you want to make sure you're buying or selling at an exact price, use a limit order.

Click the Open button and your broker will execute your order.

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Step 6: Keep an eye on your PTGX investment

Now that you own some PTGX stock, you'll want to stay up-to-date on your new company.

Put PTGX on a watchlist to get notified of the latest news about your PTGX stock.

PTGX Feed

How to Buy Stock in Protagonist Therapeutics

To summarize, here are the 6 steps for buying Protagonist Therapeutics stock:

  1. Figure out where to buy Protagonist Therapeutics stock
  2. Open your brokerage account
  3. Put funds into your investment account
  4. Analyze Protagonist Therapeutics stock
  5. Make your PTGX buy order
  6. Keep an eye on your PTGX investment

If you are looking for a brokerage account, eToro is our favorite venue.

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eToro is a multi-asset investment platform. The value of your investments may go up or down. Your capital is at risk.

If you want to keep an eye on your investment in Protagonist Therapeutics, click the button below.

NASDAQ: PTGX
$101.68+4.59 (+4.73%)
Updated Mar 19, 2026
Open eToro Account
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NASDAQ: PTGX
$101.68+4.59 (+4.73%)
Updated Mar 19, 2026
Open eToro Account
Your capital is at risk.

FAQ

How much does it cost to buy one Protagonist Therapeutics share?

As of Mar 19, 2026, it costs $101.68 to buy one share of Protagonist Therapeutics stock.

Remember, eToro's fractional share buying allows you to buy partial shares of stocks and ETFs. Even if you only have $10, you can buy 0.098 shares of PTGX.

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Is now a good time to buy Protagonist Therapeutics stock?

According to 12 Wall Street analysts who monitor Protagonist Therapeutics, their consensus recommendation is to buy Protagonist Therapeutics stock.

What is the best way to buy Protagonist Therapeutics stock?

One way to place an order for Protagonist Therapeutics stock is with a brokerage account.
WallStreetZen does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.

Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.