Protagonist Therapeutics, Inc. , a biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address hematology and blood disorders, and inflammatory and immunomodulatory diseases.
Protagonist Therapeutics stock last closed at $101.68, up 4.73% from the previous day, and has increased 87.08% in one year. It has overperformed other stocks in the Biotechnology industry by 1.32 percentage points. Protagonist Therapeutics stock is currently +156.77% from its 52-week low of $39.60, and -3.79% from its 52-week high of $105.69.
There are currently 63.81M PTGX shares outstanding. The market value of PTGX is $6.49B. In the last 24 hours, 1.92M PTGX shares were traded.
How to Buy Protagonist Therapeutics Stock
Not sure how to invest in Protagonist Therapeutics stock? Here's how.
Figure out where to buy Protagonist Therapeutics stock: You need to pick a stock brokerage, but don't worry - we've sifted through dozens of online stock brokerages and apps to help you decide where to buy Protagonist Therapeutics stock.
Open your brokerage account: Sign up for 0% fee trading with the highest-rated brokerage we've identified.
Put funds into your investment account: Select your method of payment and add your info.
Analyze Protagonist Therapeutics stock: The Protagonist Therapeutics ticker symbol is PTGX. Is Protagonist Therapeutics stock a good investment? Should you buy shares of PTGX? How do PTGX's underlying business fundamentals look? Do top analysts think Protagonist Therapeutics is a good buy? Why has PTGX's stock price moved recently? (Hint: Our stock market analysis tools can help you evaluate if PTGX is a good stock to buy).
Make your PTGX buy order: Decide if you will purchase PTGX shares at the current market price or use a limit order to purchase PTGX stock at a given price.
Keep an eye on your PTGX investment: Create a watchlist to monitor your investment in Protagonist Therapeutics stock.
Step 1: Figure out where to buy Protagonist Therapeutics stock
You will need an online brokerage account to access the NASDAQ market and buy PTGX stock.
A brokerage account is an investment account that enables you to buy and sell a number of investments, such as stocks, bonds, mutual funds, and ETFs.
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Step 2: Open your brokerage account
Now that you've selected the best brokerage, you'll need to fill out some personal details so you can invest in PTGX stock today.
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Step 4: Analyze Protagonist Therapeutics stock
After you have selected the best place to buy Protagonist Therapeutics stock, it's absolutely critical to research their stock prior to investing, so you truly wrap your head around the risk as well as the opportunity.
Protagonist Therapeutics stock data
PTGX Price
$101.68
1w %
6.56%
1y %
87.08%
5y %
226.42%
P/E
-49.6x
P/B
10.55x
P/S
140.44x
PEG
N/A
Revenue
$46.02M
Earnings
-$130.15M
Fore. Rev. Growth
70.67%
Fore. Earn. Growth
N/A
Market Cap
$6.49B
Next Earnings
May 6, 2026
Next Dividend
N/A
Fundamentals of Protagonist Therapeutics
WallStreetZen was built to help average investors do more accurate fundamental analysis quickly.
PTGX's operating cash flow of $57.67M allows it to safely service it's debt of $10.32M.
There are more short-term assets than short-term liabilities on the PTGX balance sheet.
There are more short-term assets than long-term liabilities on the PTGX balance sheet.
PTGX has a low debt to equity ratio of 0.09.
Total PTGX debt is lower than 5 years ago, relative to shareholder equity.
Signs that PTGX is not financially healthy:
PTGX earnings of -$129.31M is not enough to cover its interest payments.
PTGX profit margin has gone down from 63.3% to -282.8% in the past year.
Is it a good time to buy Protagonist Therapeutics stock, according to Wall Street analysts?
Out of 12 Equities analysts who monitor PTGX, the consensus analyst rating on Protagonist Therapeutics is a Strong Buy
Please note that analyst ratings are not stock recommendations, nor are they investment advice.
Most Recent PTGX Analyst Upgrades/Downgrades
Tara Bancroft, a top 33% analyst from TD Cowen maintains PTGX with a strong buy rating and raises their PTGX price target from $90.00 to $100.00, on Feb 26, 2026.
Jonathan Wolleben, a top 3% analyst from Citizens maintains PTGX with a buy rating and raises their PTGX price target from $102.00 to $112.00, on Feb 26, 2026.
Roger Song, a top 19% analyst from Jefferies maintains PTGX with a strong buy rating and raises their PTGX price target from $95.00 to $118.00, on Feb 2, 2026.
Douglas Tsao, a top 2% analyst from HC Wainwright & Co. maintains PTGX with a buy rating and raises their PTGX price target from $80.00 to $117.00, on Jan 30, 2026.
Srikripa Devarakonda, a top 12% analyst from Truist Securities maintains PTGX with a strong buy rating and raises their PTGX price target from $88.00 to $110.00, on Jan 5, 2026.
Truist Securities's Srikripa Devarakonda raised their price target on Protagonist Therapeutics (NASDAQ: PTGX) by 25% from $88 to $110 on 2026/01/05. The analyst maintained their Strong Buy rating on the stock.
Contextualizing their price target hike on Protagonist Therapeutics, Devarakonda predicted that 2026 will be a key year for the company because:
Rusfertide is expected to be under regulatory review.
ICO approval in PsO expected.
Upside to the stock price from pipeline progress is possible.
Last year, PTGX revenue was $46.02M. Over the past 5 year, PTGX's revenue has increased by 9.96% per year. This was slower than the Biotechnology industry average of 29.02%.
No, Protagonist Therapeutics doesn't provide an income stream by paying out dividends.
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Step 5: Make your PTGX buy order
There are two primary types of orders:
Market order: A market order is an order to buy or sell a security at the best price on the market. Market orders are usually sufficient.
Limit order: A limit order is an order to buy or sell a security at a specific price (or better). If you want to make sure you're buying or selling at an exact price, use a limit order.
Click the Open button and your broker will execute your order.
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How much does it cost to buy one Protagonist Therapeutics share?
As of Mar 19, 2026, it costs $101.68 to buy one share of Protagonist Therapeutics stock.
Remember, eToro's fractional share buying allows you to buy partial shares of stocks and ETFs. Even if you only have $10, you can buy 0.098 shares of PTGX.
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Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.