How to Buy Apellis Pharmaceuticals Stock

Apellis Pharmaceuticals Inc

Apellis Pharmaceuticals, Inc. , a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapeutic compounds through the inhibition of the complement system for autoimmune and inflammatory diseases.

Apellis Pharmaceuticals stock last closed at $20.96, down 3.14% from the previous day, and has decreased 19.38% in one year. It has underperformed other stocks in the Biotechnology industry by 0.02 percentage points. Apellis Pharmaceuticals stock is currently +30.19% from its 52-week low of $16.10, and -31.23% from its 52-week high of $30.48.

There are currently 127.83M APLS shares outstanding. The market cap of APLS is $2.68B. In the last 24 hours, 1.87M APLS shares were traded.

How to Buy Apellis Pharmaceuticals Stock

Wondering how to invest in Apellis Pharmaceuticals stock? Here's how.

  1. Decide where to buy Apellis Pharmaceuticals stock: You need to choose a stock brokerage, but don't worry - we've tested dozens of online stock brokerages and apps to help you determine where to buy Apellis Pharmaceuticals stock.
  2. Sign up for a brokerage account: Sign up for 0% commission trading with the highest-rated brokerage we've identified.
  3. Deposit money your investment account: Choose your payment method and add your info.
  4. Analyze Apellis Pharmaceuticals stock: The Apellis Pharmaceuticals ticker symbol is APLS. Is Apellis Pharmaceuticals stock a good investment? Should you buy shares of APLS? How do APLS's underlying business fundamentals look? Do top analysts think Apellis Pharmaceuticals is a good buy? Why has APLS's stock price moved recently? (Hint: Our stock market analysis website can help you figure out if APLS is a good stock to buy).
  5. Execute your APLS trade: Decide if you will purchase APLS shares at the current market price or use a limit order to buy APLS shares at a given price.
  6. Keep tabs on your APLS position: Create a watchlist to keep tabs on your position in Apellis Pharmaceuticals stock.

Step 1: Decide where to buy Apellis Pharmaceuticals stock

You will need a brokerage account to access the NASDAQ market and buy APLS shares.

A brokerage account is an investment account that enables you to buy and sell a variety of financial instruments, such as stocks, bonds, mutual funds, and ETFs.

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Step 2: Sign up for a brokerage account

Now that you've picked the right brokerage, the next step is to fill out some personal info so you are able to buy APLS today.

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Step 4: Analyze Apellis Pharmaceuticals stock

After you have selected the best place to buy Apellis Pharmaceuticals stock, it's absolutely critical to analyze their stock prior to buying, so you actually understand the risk and upside.

Overview of key APLS info

APLS Price
$20.96
1w %
-5.92%
1y %
-19.38%
5y %
-56.04%
P/E
116.44x
P/B
7.24x
P/S
2.63x
PEG
1.79x
Revenue
$1.00B
Earnings
$22.39M
Fore. Rev. Growth
7.89%
Fore. Earn. Growth
65.09%
Market Cap
$2.68B
Next Earnings
Mar 4, 2026
Next Dividend
N/A

Apellis Pharmaceuticals Due Diligence Score

WallStreetZen was created to help average investors perform more in-depth fundamental analysis quickly.

You can see all of the due diligence checks on APLS's stock page.

Is APLS stock undervalued or overvalued?

Analysts use many financial metrics, analyses, models, and charts to gauge APLS's intrinsic value.

Using relative valuations metrics:

  • APLS may be overvalued based on its P/E ratio of 116.44x, relative to Biotechnology industry P/E ratio of 36.31x
  • APLS may be overvalued based on its P/B ratio of 7.24x, relative to Biotechnology industry P/B ratio of 4.92x
  • APLS could be overvalued based on its PEG ratio of 1.79x

You can access more valuation analysis on APLS's stock here.

A look at APLS Cashflows and Balance Sheet

Passed Health Checks:

  • There are more short-term assets than long-term liabilities on the APLS balance sheet.
  • APLS profit margin has gone up from -25.3% to 2.2% in the past year.
  • There are more short-term assets than short-term liabilities on the APLS balance sheet.
  • Total APLS debt is lower than 5 years ago, relative to shareholder equity.

Failed Health Checks:

  • APLS earnings of $68.44M is not enough to cover its interest payments.
  • APLS has a relatively high debt to equity ratio of 1.91.
  • APLS's operating cash flow of $45.33M allows it to safely service it's debt of $474.36M.

Do Wall Street analysts think it's a good time to buy APLS stock

Out of 15 sell side analysts who monitor APLS, the consensus analyst rating on APLS is a Buy

It's important to keep in mind that analyst ratings are not stock recommendations, nor are they financial advice.

Latest APLS Analyst Forecasts

Tazeen Ahmad, a top 27% analyst from Bank of America upgrades APLS to a strong buy rating and maintains their APLS price target from $28.00 to $28.00, on Jan 21, 2026.

Derek Archila, a top 2% analyst from Wells Fargo maintains APLS with a strong buy rating and lowers their APLS price target from $29.00 to $26.00, on Jan 20, 2026.

Steve Seedhouse, a top 38% analyst from Cantor Fitzgerald maintains APLS with a strong buy rating and lowers their APLS price target from $39.00 to $35.00, on Jan 13, 2026.

Joseph Stringer, a top 1% analyst from Needham maintains APLS with a buy rating and lowers their APLS price target from $29.00 to $28.00, on Jan 13, 2026.

Annabel Samimy, a top 7% analyst from Stifel Nicolaus maintains APLS with a strong buy rating and lowers their APLS price target from $55.00 to $48.00, on Dec 19, 2025.

You can dig deeper into what analysts are forecasting on the Apellis Pharmaceuticals stock forecast page.

APLS Momentum

SMA10
21.92
SMA20
22.34
SMA50
23.15
SMA100
23.14
SMA200
22.36
MACD
-0.35
MACD Signal
-0.25
MACD Histogram
-0.09
RSI
39.76
Stochastic %K
33.28
Stochastic %D
39.12
StochRSI %K
5.44
StochRSI %D
19.51

How is APLS performing as a company?

Last year, APLS revenue was $1.00B. Over the past 5 year, APLS's revenue has increased by 31.98% per year. This was slower than the Biotechnology industry average of 32.76%.

You can analyze APLS's earnings and revenue performance here.

Who is buying/selling APLS?

Over the past year, insiders at APLS have sold more shares than they have bought.

Mark Jeffrey Delong, Chief Business Strat Officer of APLS, was the latest APLS insider to sell. They sold $8,152.67 worth of APLS shares on Feb 11, 2026.

Learn more about who owns APLS shares here.

Can I rely on APLS as an income stream?

No, Apellis Pharmaceuticals doesn't provide an income stream by paying out dividends.

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Step 5: Execute your APLS trade

There are two main options:

  • Market order: A market order is an order to buy or sell a security at the best available price.
    Market orders are usually the best for newer investors.
  • Limit order: A limit order enables you to buy or sell a stock at a specific price (or better).
    If you want to be certain you're buying or selling at a specific price limit, use a limit order.

Press the Open button and your broker will execute your order.

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Step 6: Keep tabs on your APLS position

Now that you own some shares in APLS, you'll want to keep up with your new investment.

Create a watchlist to monitor your APLS stock.

APLS Feed

How to Buy Stock in Apellis Pharmaceuticals

To reiterate, here are the 6 steps to buy stock in Apellis Pharmaceuticals:

  1. Decide where to buy Apellis Pharmaceuticals stock
  2. Sign up for a brokerage account
  3. Deposit money your investment account
  4. Analyze Apellis Pharmaceuticals stock
  5. Execute your APLS trade
  6. Keep tabs on your APLS position

If you need a brokerage account, eToro is our recommended venue.

Get Started with eToro Today
eToro is a multi-asset investment platform. The value of your investments may go up or down. Your capital is at risk.

If you would like to monitor your new investment in Apellis Pharmaceuticals, create a watchlist on WallStreetZen today.

NASDAQ: APLS
$20.96-0.68 (-3.14%)
Updated Feb 27, 2026
Open eToro Account
Your capital is at risk.
NASDAQ: APLS
$20.96-0.68 (-3.14%)
Updated Feb 27, 2026
Open eToro Account
Your capital is at risk.

FAQ

How much does it cost to buy one Apellis Pharmaceuticals share?

As of Feb 27, 2026, it costs $20.96 to buy one share of Apellis Pharmaceuticals stock.

Remember, eToro's fractional share buying allows you to buy partial shares of stocks and ETFs. Even if you only have $10, you can buy 0.477 shares of APLS.

Get Started with eToro Today
eToro is a multi-asset investment platform. The value of your investments may go up or down. Your capital is at risk.

Is now a good time to buy Apellis Pharmaceuticals stock?

According to 15 Wall Street analysts who monitor Apellis Pharmaceuticals, their consensus recommendation is to buy Apellis Pharmaceuticals stock.

What is the best way to buy Apellis Pharmaceuticals stock?

One way to place an order for Apellis Pharmaceuticals stock is with a brokerage account.
WallStreetZen does not provide financial advice and does not issue recommendations or offers to buy stock or sell any security.

Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.