Alnylam Pharmaceuticals, Inc. , a biopharmaceutical company, focuses on discovering, developing, and commercializing novel therapeutics based on ribonucleic acid interference.
Alnylam Pharmaceuticals stock last closed at $295.50, down 0.66% from the previous day, and has increased 1.86% in one year. It has overperformed other stocks in the Biotechnology industry by 0.77 percentage points. Alnylam Pharmaceuticals stock is currently +3.95% from its 52-week low of $284.28, and -40.37% from its 52-week high of $495.55.
There are currently 133.51M ALNY shares outstanding. The market value of ALNY is $39.45B. In the last 24 hours, 506,000 ALNY shares were traded.
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After you have chosen the best place to buy Alnylam Pharmaceuticals stock, it's critical to analyze their stock prior to investing, so you can understand the risk as well as the opportunity.
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You can see all of the due diligence checks on ALNY's stock page.
Investors use many financial metrics, analyses, models, and charts to gauge ALNY's intrinsic value.
Using relative valuations ratios:
You can access additional valuation analysis on ALNY's stock here.
Out of 15 sell side analysts who track ALNY, the consensus analyst rating on Alnylam Pharmaceuticals is a Strong Buy
Please note that analyst ratings are not recommendations, nor are they financial advice.
Keay Nakae, a top 5% analyst from Chardan Capital maintains ALNY with a strong buy rating and maintains their ALNY price target from $425.00 to $425.00, on Mar 25, 2026.
Faisal Khurshid, a top 10% analyst from Jefferies downgrades ALNY to a hold rating and lowers their ALNY price target from $522.00 to $330.00, on Mar 16, 2026.
Ilya Zubkov, a bottom 5% analyst from Freedom Broker upgrades ALNY to a strong buy rating and lowers their ALNY price target from $470.00 to $410.00, on Feb 17, 2026.
Whitney Ijem, a top 6% analyst from Canaccord Genuity maintains ALNY with a strong buy rating and raises their ALNY price target from $415.00 to $429.00, on Feb 17, 2026.
Canaccord Genuity's Whitney Ijem raised their price target on Alnylam Pharmaceuticals (NASDAQ: ALNY) by 3.4% from $415 to $429 on 2026/02/17. The analyst maintained their Strong Buy rating on the stock.
Alnylam Pharmaceuticals reported its Q4 and FY 2025 earnings.
Ijem said they revised their model in light of the unremarkable results, which followed Alnylam Pharmaceuticals' 2026/01 preannouncement of modest top and bottom line miss
However, at a macro level, Amvuttra's launch in TTR is off to a great start, the analyst said, adding that management and the Street both expect upside going forward.
Alnylam Pharmaceuticals reported:
For Q4 2025:
For FY 2025:
Management did not provide EPS and total revenue in its press release.
CEO Yvonne Greenstreet, M.D. commented: “2025 was a year of key accomplishments for Alnylam, highlighted by the landmark approval of AMVUTTRA for ATTR-CM in the U.S., which drove total net product revenues of nearly $3B, or 81% growth Y/Y, and propelled us to profitability.
“We also achieved great progress across our portfolio, initiating three Phase 3 studies, expanding our pipeline with four proprietary CTAs, and launching a potential best-in-class enzymatic ligation-based RNAi manufacturing platform.
“Further, we are excited to have recently unveiled our new set of five-year aspirational goals, Alnylam 2030, under which we aim to achieve global TTR leadership with a durable franchise; grow through innovation by delivering therapies that prevent, halt, or reverse disease; and scale with financial discipline and agility.
“By pursuing these ambitious goals, we believe Alnylam will drive substantial patient impact by addressing serious unmet medical needs around the world and create substantial long-term shareholder value.”
Joseph Stringer, a top 2% analyst from Needham maintains ALNY with a buy rating and lowers their ALNY price target from $529.00 to $510.00, on Feb 12, 2026.
You can dive deeper into what analysts are saying on the Alnylam Pharmaceuticals stock forecast page.
Last year, ALNY revenue was $4.29B. During the past five year, ALNY's revenue has increased by 49.66% per year. This was faster than the Biotechnology industry average of 30.44%.
You can research ALNY's earnings and revenue performance here.
Over the last 12 months, executives and large shareholders at ALNY have sold more shares than they have bought.
Amy W. Schulman, Director of ALNY, was the latest ALNY insider to buy. They bought $789,750.00 worth of ALNY shares on May 13, 2026.
Get more info about who owns ALNY shares here.
No, Alnylam Pharmaceuticals doesn't provide an income stream by paying out dividends.
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