Alnylam Pharmaceuticals, Inc. , a biopharmaceutical company, focuses on discovering, developing, and commercializing novel therapeutics based on ribonucleic acid interference.
Alnylam Pharmaceuticals stock last closed at $454.38, down 2.82% from the previous day, and has increased 63.84% in one year. It has overperformed other stocks in the Biotechnology industry by 1.24 percentage points. Alnylam Pharmaceuticals stock is currently +120.71% from its 52-week low of $205.87, and -3.28% from its 52-week high of $469.81.
As of Aug 22, 2025, there are 131.08M ALNY shares outstanding. The market cap of ALNY is $59.56B. In the last 24 hours, 1.08M ALNY shares were traded.
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Once you have selected the best place to buy Alnylam Pharmaceuticals stock, it's crucial to analyze their stock prior to investing, so you can comprehend the risk as well as the upside.
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You can view all of the due diligence checks on ALNY's stock page.
Investors use a variety of different financial metrics, analyses, models, and charts to gauge ALNY's intrinsic value.
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Out of 21 Wall Street analysts who give ratings on ALNY, the consensus analyst rating on ALNY is a Strong Buy
It's important to note that analyst forecasts are not recommendations, nor are they financial advice.
Whitney Ijem, a top 6% analyst from Canaccord Genuity maintains ALNY with a strong buy rating and raises their ALNY price target from $390.00 to $415.00, on Aug 1, 2025.
Canaccord Genuity's Whitney Ijem raised their price target on Alnylam Pharmaceuticals (NASDAQ: ALNY) by 6.4% from $390 to $415 on 2025/08/01. The analyst maintained their Strong Buy rating on the stock.
Alnylam Pharmaceuticals reported its Q2 2025 earnings.
The company delivered an outstanding quarter, with Amvuttra sales above expectations, resulting in higher-than-expected guidance, Ijem summarized for readers.
For Q2 2025, Alnylam Pharmaceuticals reported:
For FY 2025, management guided:
CEO Yvonne Greenstreet, M.D. commented: “Our results during Q2 highlight Alnylam’s unique ability to quickly deliver and enable commercial access to innovative medicines for patients, while continuing to advance our high-value pipeline of investigational RNAi therapeutics.
“Our first full quarter of AMVUTTRA sales in ATTR-CM provided a significant inflection in our TTR franchise revenues, with total net product revenues growing 64% Y/Y.
“While still early in the launch, we are very encouraged by the initial pace of uptake, evidence of the clear need for a novel mechanism in ATTR-CM, and the effectiveness of our broad patient access efforts.
“Based on the strong progress during 1H 2025 and our confidence in the overall business for the rest of the year, we are raising our total net product revenue guidance range by 27% at the midpoint, driven by an upward revision to our TTR franchise revenue guidance.
“We also continue to advance key programs in our robust pipeline, with the TRITON-CM Phase 3 trial of nucresiran in ATTR-CM underway, and two more Phase 3 trials on track to start this year: TRITON-PN for nucresiran in hATTR-PN and the cardiovascular outcomes trial of zilebesiran in hypertension.
“The remarkable pace and depth of our progress positions us to deliver on our Alnylam P5x25 goals as we advance toward sustainable profitability and solidify ourselves as a top-tier biotech company delivering transformational innovation to patients.”
Tiago Fauth, a top 32% analyst from Wells Fargo maintains ALNY with a hold rating and raises their ALNY price target from $333.00 to $395.00, on Aug 1, 2025.
Martin Auster, a top 26% analyst from Raymond James reiterates ALNY with a buy rating and raises their ALNY price target from $370.00 to $424.00, on Aug 1, 2025.
Gena Wang, a bottom 6% analyst from Barclays maintains ALNY with a strong buy rating and raises their ALNY price target from $329.00 to $460.00, on Aug 1, 2025.
Edward Tenthoff, a bottom 1% analyst from Piper Sandler maintains ALNY with a strong buy rating and raises their ALNY price target from $304.00 to $449.00, on Aug 1, 2025.
You can dive deeper into what analysts are forecasting on the Alnylam Pharmaceuticals stock forecast page.
Last year, ALNY revenue was $2.46B. Over the last 5 year, ALNY's revenue has increased by 48.13% per year. This was slower than the Biotechnology industry average of 65.21%.
You can analyze ALNY's earnings and revenue performance here.
In the last year, insiders at ALNY have sold more shares than they have bought.
Pushkal Garg, EVP Chief RD of ALNY, was the latest ALNY insider to sell. They sold $125,693.16 worth of ALNY shares on Aug 19, 2025.
Research more about who owns ALNY shares here.
No, Alnylam Pharmaceuticals doesn't provide an income stream by paying out dividends.
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