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NASDAQ: UPB
Upstream Bio Inc Earnings Dates, Reports, Calls

OverviewForecastEarnings
RevenueDividendOwnership
Upstream Bio earnings were -$143.4M for the trailing 12 months ending Dec 31, 2025, with N/A growth year over year. The latest UPB earnings report on Dec 31, 2025 announced Q4 2025 earnings of -$42.5M, up 25.8% from last quarter. For the last reported fiscal year 2025 ending Dec 31, 2025, UPB reported annual earnings of -$143.4M, with 87.8% growth. The next UPB earnings date is May 12, 2026.

UPB earnings history

Current Revenue
$2.9M
Current Earnings
-$143.4M
Current Profit Margin
-5,026%

UPB Return on Equity

Current Company
-36.5%
Current Industry
-30.5%
Current Market
28.9%
UPB's Return on Equity (-36.5%)... subscribe to Premium to read more.
High Return on Equity Performance

UPB Return on Assets

Current Company
-35.4%
Current Industry
-9.2%
UPB is generating lower Return... subscribe to Premium to read more.
Above Average Return on Assets Performance

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UPB Return on Capital Employed

Current Company
-42.15%
Current Industry
-3.2%
UPB has gotten more efficient... subscribe to Premium to read more.
Increasing Return on Capital Employed Performance

UPB vs Biotech Stocks

TickerEBITDAEarningsY/Y EarningsEPS
UPB-$142.69M-$143.44MN/A-$2.66
KYTX-$156.12M-$161.31MN/A-$3.64
ADCT-$88.10M-$142.62MN/A-$1.12
FDMT-$132.48M-$140.11MN/A-$2.42
RIGL$131.56M$367.02M+1,960.61%$20.40
View Top Biotech Stocks

UPB earnings dates

Next earnings date
May 12, 2026

Upstream Bio Earnings Reports & History FAQ

What were Upstream Bio's earnings last quarter?

On UPB's earnings call on Invalid Date, Upstream Bio (NASDAQ: UPB) reported Q4 2025 earnings per share (EPS) of -$0.78, up 106.21% year over year. Total UPB earnings for the quarter were -$42.46 million. In the same quarter last year, Upstream Bio's earnings per share (EPS) was $12.57.

If you're new to stock investing, here's how to buy Upstream Bio stock.

When does Upstream Bio report earnings?

The next UPB earnings call is Invalid Date. Add UPB to your watchlist to be reminded of Upstream Bio's next earnings date.

Is Upstream Bio profitable or losing money?

As of the last Upstream Bio earnings report, Upstream Bio is currently losing money. Upstream Bio's net profit (also called net income) for the twelve months ending Dec 31, 2025 was -$143.44 million, a 128.39% increase year over year.

What was UPB's earnings growth in the past year?

As of Upstream Bio's earnings date in Invalid Date, Upstream Bio's earnings has grown year over year. UPB earnings in the past year totalled -$143.44 million.

What are Upstream Bio's earnings expectations?

The current EPS estimate for Upstream Bio's earnings report in Invalid Date is -$0.85.
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