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NASDAQ: UPB
Upstream Bio Inc Earnings Dates, Reports, Calls

OverviewForecastEarnings
RevenueDividendOwnership
Upstream Bio earnings were -$163.9M for the trailing 12 months ending Sep 30, 2026, with N/A growth year over year. The latest UPB earnings report on Sep 30, 2026 announced Q3 2026 earnings of -$41.2M, up 3.8% from last quarter. For the last reported fiscal year 2025 ending Dec 31, 2025, UPB reported annual earnings of -$143.4M, with 87.8% growth.

UPB earnings history

Current Revenue
$2.9M
Current Earnings
-$163.9M
Current Profit Margin
-5,712.3%

UPB Return on Equity

Current Company
-57.1%
Current Industry
-17.8%
Current Market
37.4%
UPB's Return on Equity (-57.1%)... subscribe to Premium to read more.
High Return on Equity Performance

UPB Return on Assets

Current Company
-54.7%
Current Industry
-7.5%
UPB is generating lower Return... subscribe to Premium to read more.
Above Average Return on Assets Performance

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UPB Return on Capital Employed

Current Company
-70.05%
Current Industry
-5.1%

UPB vs Biotech Stocks

TickerEBITDAEarningsY/Y EarningsEPS
UPB-$163.13M-$163.94MN/A-$3.01
IVVD-$105.32M-$107.33MN/A-$0.33
IFRX-$32.37M-$32.84MN/A-$0.38
VRXA-$80.06M-$82.24MN/A-$5.68
MDWD-$19.58M-$20.18MN/A-$1.61
View Top Biotech Stocks

Upstream Bio Earnings Reports & History FAQ

What were Upstream Bio's earnings last quarter?

On UPB's earnings call on Nov 10, 2026, Upstream Bio (NASDAQ: UPB) reported Q3 2026 earnings per share (EPS) of -$0.75, up 19.05% year over year. Total UPB earnings for the quarter were -$41.19 million. In the same quarter last year, Upstream Bio's earnings per share (EPS) was -$0.63.

If you're new to stock investing, here's how to buy Upstream Bio stock.

Is Upstream Bio profitable or losing money?

As of the last Upstream Bio earnings report, Upstream Bio is currently losing money. Upstream Bio's net profit (also called net income) for the twelve months ending Sep 30, 2026 was -$163.94 million, a 34.13% increase year over year.

What was UPB's earnings growth in the past year?

As of Upstream Bio's earnings date in Nov 10, 2026, Upstream Bio's earnings has grown year over year. UPB earnings in the past year totalled -$163.94 million.
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