| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Brian Dorsey | Chief Operating Officer | 2025-11-13 | 21,828 | $8.71 | $190.06kSell |
| Brian Dorsey | Chief Operating Officer | 2025-11-13 | 21,828 | $0.64 | $13.97kBuy |
| Justin Chakma | Chief Business Officer | 2025-11-12 | 30,000 | $0.84 | $25.20kBuy |
| Justin Chakma | Chief Business Officer | 2025-11-12 | 136,380 | $8.86 | $1.21MSell |
| Justin Chakma | Chief Business Officer | 2025-11-12 | 30,000 | $8.91 | $267.36kSell |
| Richard E. Lowenthal | PRESIDENT AND CEO | 2025-08-21 | 50,000 | $14.49 | $724.35kSell |
| Kathleen D. Scott | Chief Financial Officer | 2025-08-21 | 12,500 | $15.00 | $187.50kSell |
| Kathleen D. Scott | Chief Financial Officer | 2025-08-21 | 12,500 | $1.50 | $18.75kBuy |
| Sarina Tanimoto | CHIEF MEDICAL OFFICER | 2025-08-20 | 37,656 | $14.09 | $530.61kSell |
| Sarina Tanimoto | CHIEF MEDICAL OFFICER | 2025-08-19 | 12,344 | $14.03 | $173.12kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Richard E. Lowenthal | 22.21% | 21,952,529 | $209.65M | Insider |
| Sarina Tanimoto | 20.60% | 20,360,336 | $194.44M | Insider |
| Orbimed Advisors LLC | 17.23% | 17,029,398 | $162.63M | Insider |
| Peter A. Thompson | 17.23% | 17,029,398 | $162.63M | Insider |
| Ra Capital Management LP | 10.99% | 10,860,977 | $103.72M | Institution |
| James E. Flynn | 9.89% | 9,774,508 | $93.35M | Insider |
| Orbimed Advisors LLC | 8.39% | 8,288,510 | $79.16M | Institution |
| Deerfield Management Company LP | 7.59% | 7,503,812 | $71.66M | Institution |
| Blackrock Inc | 4.89% | 4,831,327 | $46.14M | Institution |
| Rubric Capital Management LP | 4.55% | 4,500,000 | $42.98M | Institution |