| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Eric Karas | Chief Commercial Officer | 2026-06-12 | 25,000 | $1.50 | $37.50kBuy |
| Alexander A. Fitzpatrick | Chief Legal Officer | 2026-06-12 | 3,355 | $10.00 | $33.55kSell |
| Eric Karas | Chief Commercial Officer | 2026-06-12 | 25,000 | $10.00 | $250.00kSell |
| Brian Dorsey | Chief Operating Officer | 2025-11-13 | 21,828 | $0.64 | $13.97kBuy |
| Brian Dorsey | Chief Operating Officer | 2025-11-13 | 21,828 | $8.71 | $190.06kSell |
| Justin Chakma | Chief Business Officer | 2025-11-12 | 136,380 | $8.86 | $1.21MSell |
| Justin Chakma | Chief Business Officer | 2025-11-12 | 30,000 | $0.84 | $25.20kBuy |
| Justin Chakma | Chief Business Officer | 2025-11-12 | 30,000 | $8.91 | $267.36kSell |
| Kathleen D. Scott | Chief Financial Officer | 2025-08-21 | 12,500 | $1.50 | $18.75kBuy |
| Richard E. Lowenthal | PRESIDENT AND CEO | 2025-08-21 | 50,000 | $14.49 | $724.35kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Richard E. Lowenthal | 22.11% | 21,952,529 | $211.84M | Insider |
| Sarina Tanimoto | 20.50% | 20,360,336 | $196.48M | Insider |
| Peter A. Thompson | 17.15% | 17,029,398 | $164.33M | Insider |
| Orbimed Advisors LLC | 17.15% | 17,029,398 | $164.33M | Insider |
| Ra Capital Management LP | 10.94% | 10,860,977 | $104.81M | Institution |
| James E. Flynn | 9.84% | 9,774,508 | $94.32M | Insider |
| Orbimed Advisors LLC | 8.35% | 8,288,510 | $79.98M | Institution |
| Rubric Capital Management LP | 8.06% | 8,000,000 | $77.20M | Institution |
| Deerfield Management Company LP | 7.56% | 7,503,812 | $72.41M | Institution |
| Millennium Management LLC | 6.02% | 5,982,919 | $57.74M | Institution |