| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| David P. Meeker | CEO;Pres | 2026-09-14 | 30,746 | $102.35 | $3.15MSell |
| David P. Meeker | CEO;Pres | 2026-09-14 | 2,300 | $105.19 | $241.94kSell |
| David P. Meeker | CEO;Pres | 2026-09-14 | 1,817 | $104.55 | $189.97kSell |
| David P. Meeker | CEO;Pres | 2026-09-14 | 8,698 | $103.43 | $899.63kSell |
| David P. Meeker | CEO;Pres | 2026-09-14 | 50,000 | $6.05 | $302.50kBuy |
| David P. Meeker | CEO;Pres | 2026-09-14 | 6,439 | $101.75 | $655.14kSell |
| Hunter C. Smith | CFO | 2026-08-31 | 57,187 | $25.79 | $1.47MBuy |
| Hunter C. Smith | CFO | 2026-08-31 | 28,188 | $106.20 | $2.99MSell |
| Hunter C. Smith | CFO | 2026-08-31 | 11,514 | $105.37 | $1.21MSell |
| Hunter C. Smith | CFO | 2026-08-31 | 23,072 | $104.59 | $2.41MSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Ra Capital Management LP | 6.33% | 4,360,860 | $427.41M | Insider |
| Orbimed Advisors LLC | 3.99% | 2,750,079 | $269.54M | Insider |
| Todd Foley | 1.32% | 909,258 | $89.12M | Insider |
| Keith Michael Gottesdiener | 0.81% | 558,250 | $54.71M | Insider |
| David P. Meeker | 0.35% | 239,258 | $23.45M | Insider |
| Hunter C. Smith | 0.17% | 114,024 | $11.18M | Insider |
| Third Rock Ventures LP | 0.14% | 99,105 | $9.71M | Insider |
| Yann Mazabraud | 0.08% | 55,655 | $5.45M | Insider |
| Nithya Desikan | 0.06% | 43,602 | $4.27M | Insider |
| Der Ploeg Leonardus Ht Van | 0.06% | 42,339 | $4.15M | Insider |