| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Darwin Global Management Ltd | 9.51% | 3,027,704 | $488.70M | Institution |
| Rtw Investments LP | 2.25% | 715,332 | $115.46M | Institution |
| Millennium Management LLC | 1.76% | 558,882 | $90.21M | Institution |
| Ra Capital Management LP | 1.36% | 432,484 | $69.81M | Institution |
| Perceptive Advisors LLC | 1.30% | 414,239 | $66.86M | Institution |
| Eventide Asset Management LLC | 1.20% | 383,091 | $61.83M | Institution |
| Point72 Asset Management LP | 0.89% | 284,437 | $45.91M | Institution |
| Deerfield Management Company LP | 0.73% | 233,813 | $37.74M | Institution |
| Haoyuan Chuang | 0.61% | 195,264 | $31.52M | Insider |
| Marshall Wace LLP | 0.61% | 192,700 | $31.10M | Institution |