| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Harry Shuman | VP Controller PAO | 2025-11-25 | 8,300 | $95.92 | $796.14kSell |
| Peter B. Silverman | COO GC | 2025-07-17 | 25,000 | $60.00 | $1.50MSell |
| Peter B. Silverman | COO GC | 2025-07-17 | 25,000 | $24.43 | $610.75kBuy |
| Peter B. Silverman | COO GC | 2025-07-10 | 16,805 | $55.00 | $924.28kSell |
| Peter B. Silverman | COO GC | 2025-07-10 | 16,805 | $18.61 | $312.74kBuy |
| Peter B. Silverman | COO GC | 2025-07-09 | 6,695 | $55.00 | $368.23kSell |
| Peter B. Silverman | COO GC | 2025-07-09 | 6,695 | $18.61 | $124.59kBuy |
| Peter B. Silverman | COO GC | 2025-06-20 | 34,000 | $52.76 | $1.79MSell |
| Peter B. Silverman | COO GC | 2025-06-20 | 34,000 | $18.61 | $632.74kBuy |
| Sven Ante Lundberg | President CEO PEO | 2025-04-17 | 26,500 | $13.52 | $358.28kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Paradigm Biocapital Advisors LP | 5.77% | 4,373,770 | $420.49M | Institution |
| Incyte Corp | 4.68% | 3,550,000 | $341.30M | Insider |
| Avoro Capital Advisors LLC | 4.67% | 3,542,500 | $340.58M | Institution |
| Commodore Capital LP | 4.65% | 3,525,000 | $338.89M | Institution |
| Deerfield Management Company LP | 4.02% | 3,046,916 | $292.93M | Institution |
| Hbk Investments L P | 3.76% | 2,850,000 | $274.00M | Institution |
| Fmr LLC | 3.71% | 2,810,935 | $270.24M | Institution |
| Blackrock Inc | 2.86% | 2,172,015 | $208.82M | Institution |
| Westfield Capital Management Co LP | 2.81% | 2,132,489 | $205.02M | Institution |
| Rtw Investments LP | 2.67% | 2,025,277 | $194.71M | Institution |