| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Coelho Rogerio Vivaldi | Director | 2026-03-12 | 523 | $36.77 | $19.23kSell |
| Coelho Rogerio Vivaldi | Director | 2026-03-12 | 4,477 | $36.08 | $161.53kSell |
| Stephanie Okey | Director | 2026-03-03 | 3,000 | $39.67 | $119.01kSell |
| Tobin Schilke | Chief Financial Officer | 2026-03-03 | 6,713 | $39.67 | $266.30kSell |
| Isabel Kalofonos | Chief Commercial Officer | 2026-01-05 | 2,500 | $55.00 | $137.50kSell |
| Isabel Kalofonos | Chief Commercial Officer | 2026-01-05 | 2,500 | $40.59 | $101.48kBuy |
| Stephen F. Betz | Chief Scientific Officer | 2025-12-26 | 18,000 | $1.91 | $34.38kBuy |
| Richard Scott Struthers | President CEO | 2025-12-18 | 16,342 | $9.28 | $151.65kBuy |
| Richard Scott Struthers | President CEO | 2025-12-18 | 28,400 | $15.29 | $434.24kBuy |
| Dana Pizzuti | Chief Med and Dev Officer | 2025-12-01 | 5,000 | $16.89 | $84.45kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Fmr LLC | 13.65% | 14,293,775 | $535.87M | Institution |
| Vanguard Group Inc | 8.72% | 9,135,504 | $342.49M | Institution |
| Wellington Management Group LLP | 7.68% | 8,037,889 | $301.34M | Institution |
| Blackrock Inc | 7.63% | 7,988,548 | $299.49M | Institution |
| Perceptive Advisors LLC | 7.55% | 7,908,985 | $296.51M | Insider |
| Farallon Capital Management LLC | 6.62% | 6,933,098 | $259.92M | Institution |
| Driehaus Capital Management LLC | 6.10% | 6,387,740 | $239.48M | Institution |
| Price T Rowe Associates Inc | 4.99% | 5,224,387 | $195.86M | Institution |
| Janus Henderson Group PLC | 4.24% | 4,440,691 | $166.48M | Institution |
| Ecor1 Capital LLC | 4.10% | 4,288,120 | $160.76M | Institution |