| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Isabel Kalofonos | Chief Commercial Officer | 2026-01-05 | 2,500 | $40.59 | $101.48kBuy |
| Isabel Kalofonos | Chief Commercial Officer | 2026-01-05 | 2,500 | $55.00 | $137.50kSell |
| Stephen F. Betz | Chief Scientific Officer | 2025-12-26 | 18,000 | $1.91 | $34.38kBuy |
| Richard Scott Struthers | President CEO | 2025-12-18 | 16,342 | $9.28 | $151.65kBuy |
| Richard Scott Struthers | President CEO | 2025-12-18 | 28,400 | $15.29 | $434.24kBuy |
| Dana Pizzuti | Chief Med and Dev Officer | 2025-12-01 | 5,000 | $16.89 | $84.45kBuy |
| Dana Pizzuti | Chief Med and Dev Officer | 2025-12-01 | 5,000 | $45.02 | $225.10kSell |
| Dana Pizzuti | Chief Med and Dev Officer | 2025-11-03 | 4,900 | $42.65 | $208.99kSell |
| Dana Pizzuti | Chief Med and Dev Officer | 2025-11-03 | 5,000 | $16.89 | $84.45kBuy |
| Dana Pizzuti | Chief Med and Dev Officer | 2025-11-03 | 100 | $43.27 | $4.33kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Fmr LLC | 14.95% | 14,187,498 | $736.05M | Institution |
| Vanguard Group Inc | 9.66% | 9,170,129 | $475.75M | Institution |
| Wellington Management Group LLP | 8.83% | 8,381,991 | $434.86M | Institution |
| Perceptive Advisors LLC | 8.33% | 7,908,985 | $410.32M | Insider |
| Blackrock Inc | 7.99% | 7,586,597 | $393.59M | Institution |
| Driehaus Capital Management LLC | 6.83% | 6,481,613 | $336.27M | Institution |
| Farallon Capital Management LLC | 6.08% | 5,770,098 | $299.35M | Institution |
| Price T Rowe Associates Inc | 5.59% | 5,306,248 | $275.29M | Institution |
| Ecor1 Capital LLC | 4.52% | 4,288,120 | $222.47M | Institution |
| Janus Henderson Group PLC | 4.07% | 3,858,791 | $200.19M | Institution |