Vigil Neuroscience Incorporated is a microglia-focused company that develops disease-modifying therapeutics for rare and common neurodegenerative diseases. Its lead product candidate is VGL101 is in Phase I for the treatment of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia, as well as for the treatment of cerebral adrenoleukodystrophy and alzheimer's disease. The company was incorporated in 2020 and is headquartered in Cambridge, MA.