NASDAQ: PBYI
Puma Biotechnology Inc Stock

$7.49+0.23 (+3.17%)
Updated May 8, 2026
PBYI Price
$7.49
Fair Value Price
$17.54
Market Cap
$381.24M
52 Week Low
$2.85
52 Week High
$7.90
P/E
14.98x
P/B
2.97x
P/S
1.43x
PEG
1.52x
Dividend Yield
N/A
Revenue
$227.18M
Earnings
$24.38M
Gross Margin
74.5%
Operating Margin
15.08%
Profit Margin
10.7%
Debt to Equity
0.5
Operating Cash Flow
$54M
Beta
0.99
Next Earnings
N/A
Ex-Dividend
N/A
Next Dividend
N/A

PBYI Overview

Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. The company's drug candidates include PB272 neratinib (oral) for the patients with early stage HER2-overexpressed/amplified breast cancer; PB272 (neratinib, oral) for the use of neratinib in combination with capecitabine for the treatment of adult patients with advanced or metastatic HER2-positive breast cancer; PB272 (neratinib, oral) for HER2 mutation-positive solid tumors. It has a license agreement with Pfizer, Inc.; and sub-license agreement with Specialised Therapeutics Asia Pte Ltd., CANbridge BIOMED Limited, Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd. The company was founded in 2010 and is headquartered in Los Angeles, California.

Zen Rating

Our proven quant model uses 115 proprietary factors, including AI, to determine PBYI's potential to beat the market

AStrong Buy
  • Stocks with a Zen Rating of Strong Buy (A) had an average return of +32.52% per year. Learn More

Zen Rating Component Grades

C
Zen Rating uses advanced AI algorithms that detect subtle patterns in market data; it anticipates future trends that point to superior stock price results.

Industry: Biotech

Industry Rating
F
PBYI
Ranked
#5 of 458

Top Ranked Stocks in Industry

Name / TickerPriceZen Rating
$225.79A
$48.16A
$15.23A
View Top Biotech Stocks

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PBYI News

Overview

Due Diligence Score

Industry Average (25)
You've viewed Due Diligence Score for 10/10 free stocks. Upgrade to Premium to see how PBYI scored across 33 valuation, financial, forecast, performance, and dividend due diligence checks.

Due Diligence Checks

PBYI ($7.49) is undervalued by 57.31% relative to our estimate of its Fair Value price of $17.54 based on Discounted Cash Flow (DCF) modelling, but does not have a significant margin of safety
Below Fair Value Valuation
PBYI ($7.49) is significantly undervalued by 57.31% relative to our estimate of its Fair Value price of $17.54 based on Discounted Cash Flow (DCF) modelling, which includes a healthy margin of safety
Significantly Below Fair Value Valuation
PBYI ($7.49) is trading above... subscribe to Premium to read more.
Below Benjamin Graham Formula Value Valuation
There are 30 more PBYI due diligence checks available for Premium users.

Valuation

PBYI fair value

Fair Value of PBYI stock based on Discounted Cash Flow (DCF)

Price
$7.49
Fair Value
$17.54
Undervalued by
57.31%
PBYI ($7.49) is undervalued by... subscribe to Premium to read more.
Below Fair Value Valuation
PBYI ($7.49) is significantly undervalued... subscribe to Premium to read more.
Significantly Below Fair Value Valuation
PBYI ($7.49) is trading above... subscribe to Premium to read more.
Below Benjamin Graham Formula Value Valuation

PBYI price to earnings (PE)

For valuing profitable companies with steady earnings

Company
14.98x
Industry
16.32x
Market
23.73x
PBYI is good value based... subscribe to Premium to read more.
P/E vs Industry Valuation
PBYI is good value based... subscribe to Premium to read more.
P/E vs Market Valuation

PBYI price to book (PB)

For valuing companies that are loss-making or have lots of physical asset

Company
2.97x
Industry
4.99x
PBYI is good value based... subscribe to Premium to read more.
P/B vs Industry Valuation

PBYI price to earnings growth (PEG)

For valuing profitable companies with growth potential

PBYI is poor value relative... subscribe to Premium to read more.
PEG Value Valuation

PBYI's financial health

Profit margin

Revenue
$44.8M
Net Income
-$3.8M
Profit Margin
-8.4%
PBYI's Earnings (EBIT) of $34.26M... subscribe to Premium to read more.
Interest Coverage Financials
PBYI's profit margin has decreased... subscribe to Premium to read more.
Profit Margin Growth Financials

Assets to liabilities

Assets
$192.7M
Liabilities
$64.3M
Debt to equity
0.5
PBYI's short-term assets ($142.26M) exceed... subscribe to Premium to read more.
Short-term Liabilities Financials
PBYI's short-term assets ($142.26M) exceed... subscribe to Premium to read more.
Long-term Liabilities Financials
PBYI's debt relative to shareholder... subscribe to Premium to read more.
Shrinking Debt Financials
PBYI's debt to equity ratio... subscribe to Premium to read more.
Healthy Debt to Equity Financials

Cash flow

Operating
$15.4M
Investing
$2.5M
Financing
-$11.3M
PBYI's operating cash flow ($53.61M)... subscribe to Premium to read more.
Debt Coverage Financials

PBYI vs Biotech Stocks

TickerZen RatingMarket Cap1d %P/EP/B
PBYIA$381.24M+3.17%14.98x2.97x
VNDAF$377.65M-1.72%-1.55x1.35x
YDES$375.89M+0.34%-44.25x-131.63x
EPRXD$386.95M-0.27%-7.23x4.72x
OVIDC$369.25M+2.56%-12.17x2.83x

Puma Biotechnology Stock FAQ

What is Puma Biotechnology's quote symbol?

(NASDAQ: PBYI) Puma Biotechnology trades on the NASDAQ under the ticker symbol PBYI. Puma Biotechnology stock quotes can also be displayed as NASDAQ: PBYI.

If you're new to stock investing, here's how to buy Puma Biotechnology stock.

What is the 52 week high and low for Puma Biotechnology (NASDAQ: PBYI)?

(NASDAQ: PBYI) Puma Biotechnology's 52-week high was $7.90, and its 52-week low was $2.85. It is currently -5.17% from its 52-week high and 162.81% from its 52-week low.

How much is Puma Biotechnology stock worth today?

(NASDAQ: PBYI) Puma Biotechnology currently has 50,899,456 outstanding shares. With Puma Biotechnology stock trading at $7.49 per share, the total value of Puma Biotechnology stock (market capitalization) is $381.24M.

Puma Biotechnology stock was originally listed at a price of $14.00 in Apr 24, 2012. If you had invested in Puma Biotechnology stock at $14.00, your return over the last 14 years would have been -46.5%, for an annualized return of -4.37% (not including any dividends or dividend reinvestments).

How much is Puma Biotechnology's stock price per share?

(NASDAQ: PBYI) Puma Biotechnology stock price per share is $7.49 today (as of May 8, 2026).

What is Puma Biotechnology's Market Cap?

(NASDAQ: PBYI) Puma Biotechnology's market cap is $381.24M, as of May 11, 2026.

Market cap (market capitalization) is the total market value of a publicly traded company's outstanding shares.

Puma Biotechnology's market cap is calculated by multiplying PBYI's current stock price of $7.49 by PBYI's total outstanding shares of 50,899,456.
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