NASDAQ: PBYI
Puma Biotechnology Inc Stock

$8.00+0.10 (+1.27%)
Updated Jul 10, 2026
PBYI Price
$8.00
Fair Value Price
$17.56
Market Cap
$407.20M
52 Week Low
$3.03
52 Week High
$8.44
P/E
16x
P/B
3.17x
P/S
1.43x
PEG
N/A
Dividend Yield
N/A
Revenue
$227.18M
Earnings
$24.38M
Gross Margin
74.5%
Operating Margin
15.08%
Profit Margin
10.7%
Debt to Equity
0.5
Operating Cash Flow
$54M
Beta
0.98
Next Earnings
Aug 6, 2026
Ex-Dividend
N/A
Next Dividend
N/A

PBYI Overview

Puma Biotechnology, Inc. is a biopharmaceutical company dedicated to the global development and commercialization of treatments aimed at advancing cancer care. Its lead drug candidate, orally administered neratinib (PB272), targets a range of indications. These include patients with early-stage HER2-overexpressed/amplified breast cancer, as well as adults suffering from advanced or metastatic HER2-positive breast cancer when used in combination with capecitabine. Furthermore, PB272 is being explored for solid tumors exhibiting HER2 mutations. The company holds a licensing agreement with Pfizer, Inc. for this drug and has established sub-licensing partnerships with Specialised Therapeutics Asia Pte Ltd., CANbridge BIOMED Limited, Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd. Established in 2010, Puma Biotechnology maintains its headquarters in Los Angeles, California.

Zen Rating

Our proven quant model uses 115 proprietary factors, including AI, to determine PBYI's potential to beat the market

BBuy
  • Stocks with a Zen Rating of Buy (B) had an average return of +17.17% per year. Learn More

Zen Rating Component Grades

C
Zen Rating uses advanced AI algorithms that detect subtle patterns in market data; it anticipates future trends that point to superior stock price results.

Industry: Biotech

Industry Rating
F
PBYI
Ranked
#16 of 464

Top Ranked Stocks in Industry

Name / TickerPriceZen Rating
$10.89A
$56.50A
$15.78A
View Top Biotech Stocks

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PBYI News

Overview

Due Diligence Score

Industry Average (24)
You've viewed Due Diligence Score for 10/10 free stocks. Upgrade to Premium to see how PBYI scored across 33 valuation, financial, forecast, performance, and dividend due diligence checks.

Due Diligence Checks

PBYI ($8.00) is undervalued by 54.43% relative to our estimate of its Fair Value price of $17.56 based on Discounted Cash Flow (DCF) modelling, but does not have a significant margin of safety
Below Fair Value Valuation
PBYI ($8.00) is significantly undervalued by 54.43% relative to our estimate of its Fair Value price of $17.56 based on Discounted Cash Flow (DCF) modelling, which includes a healthy margin of safety
Significantly Below Fair Value Valuation
PBYI is forecast by analysts... subscribe to Premium to read more.
Below Benjamin Graham Formula Value Valuation
There are 30 more PBYI due diligence checks available for Premium users.

Valuation

PBYI fair value

Fair Value of PBYI stock based on Discounted Cash Flow (DCF)

Price
$8.00
Fair Value
$17.56
Undervalued by
54.43%
PBYI ($8.00) is undervalued by... subscribe to Premium to read more.
Below Fair Value Valuation
PBYI ($8.00) is significantly undervalued... subscribe to Premium to read more.
Significantly Below Fair Value Valuation
PBYI is forecast by analysts... subscribe to Premium to read more.
Below Benjamin Graham Formula Value Valuation

PBYI price to earnings (PE)

For valuing profitable companies with steady earnings

Company
16x
Industry
17.05x
Market
12.99x
PBYI is good value based... subscribe to Premium to read more.
P/E vs Industry Valuation
PBYI is poor value based... subscribe to Premium to read more.
P/E vs Market Valuation

PBYI price to book (PB)

For valuing companies that are loss-making or have lots of physical asset

Company
3.17x
Industry
5.52x
PBYI is good value based... subscribe to Premium to read more.
P/B vs Industry Valuation

PBYI's financial health

Profit margin

Revenue
$44.8M
Net Income
-$3.8M
Profit Margin
-8.4%
PBYI's Earnings (EBIT) of $34.26M... subscribe to Premium to read more.
Interest Coverage Financials
PBYI's profit margin has decreased... subscribe to Premium to read more.
Profit Margin Growth Financials

Assets to liabilities

Assets
$192.7M
Liabilities
$64.3M
Debt to equity
0.5
PBYI's short-term assets ($142.26M) exceed... subscribe to Premium to read more.
Short-term Liabilities Financials
PBYI's short-term assets ($142.26M) exceed... subscribe to Premium to read more.
Long-term Liabilities Financials
PBYI's debt relative to shareholder... subscribe to Premium to read more.
Shrinking Debt Financials
PBYI's debt to equity ratio... subscribe to Premium to read more.
Healthy Debt to Equity Financials

Cash flow

Operating
$15.4M
Investing
$2.5M
Financing
-$11.3M
PBYI's operating cash flow ($53.61M)... subscribe to Premium to read more.
Debt Coverage Financials

PBYI vs Biotech Stocks

TickerZen RatingMarket Cap1d %P/EP/B
PBYIB$407.20M+1.27%16.00x3.17x
IPSCD$405.80M-2.60%-1.97x1.53x
UPBD$409.78M-3.59%-2.60x1.35x
EPRXF$412.88M-3.33%-6.36x3.00x
DMACD$413.29M-0.52%-10.80x8.75x

Puma Biotechnology Stock FAQ

What is Puma Biotechnology's quote symbol?

(NASDAQ: PBYI) Puma Biotechnology trades on the NASDAQ under the ticker symbol PBYI. Puma Biotechnology stock quotes can also be displayed as NASDAQ: PBYI.

If you're new to stock investing, here's how to buy Puma Biotechnology stock.

What is the 52 week high and low for Puma Biotechnology (NASDAQ: PBYI)?

(NASDAQ: PBYI) Puma Biotechnology's 52-week high was $8.44, and its 52-week low was $3.03. It is currently -5.21% from its 52-week high and 164.03% from its 52-week low.

How much is Puma Biotechnology stock worth today?

(NASDAQ: PBYI) Puma Biotechnology currently has 50,899,456 outstanding shares. With Puma Biotechnology stock trading at $8.00 per share, the total value of Puma Biotechnology stock (market capitalization) is $407.20M.

Puma Biotechnology stock was originally listed at a price of $14.00 in Apr 24, 2012. If you had invested in Puma Biotechnology stock at $14.00, your return over the last 14 years would have been -42.86%, for an annualized return of -3.92% (not including any dividends or dividend reinvestments).

How much is Puma Biotechnology's stock price per share?

(NASDAQ: PBYI) Puma Biotechnology stock price per share is $8.00 today (as of Jul 10, 2026).

What is Puma Biotechnology's Market Cap?

(NASDAQ: PBYI) Puma Biotechnology's market cap is $407.20M, as of Jul 12, 2026.

Market cap (market capitalization) is the total market value of a publicly traded company's outstanding shares.

Puma Biotechnology's market cap is calculated by multiplying PBYI's current stock price of $8.00 by PBYI's total outstanding shares of 50,899,456.
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