NASDAQ: STOK
Stoke Therapeutics Inc Stock

$31.62-0.97 (-2.98%)
Updated Aug 28, 2026
STOK Price
$31.62
Fair Value Price
N/A
Market Cap
$2.04B
52 Week Low
$18.80
52 Week High
$40.22
P/E
-9.38x
P/B
5.9x
P/S
78.3x
PEG
N/A
Dividend Yield
N/A
Revenue
$27.59M
Earnings
-$207.90M
Gross Margin
100%
Operating Margin
-808.9%
Profit Margin
-753.6%
Debt to Equity
0.14
Operating Cash Flow
-$178M
Beta
1.38
Next Earnings
N/A
Ex-Dividend
N/A
Next Dividend
N/A

STOK Overview

Stoke Therapeutics, Inc. is an emerging biopharmaceutical company dedicated to developing innovative antisense oligonucleotide (ASO) therapies. Its primary focus is to target and address the fundamental causes of severe genetic disorders, particularly within the United States. The company employs its exclusive Targeted Augmentation of Nuclear Gene Output (TANGO) platform to engineer ASOs that precisely enhance protein expression. Stoke's most advanced candidate, STK-001, is currently progressing through Phase I/IIa clinical trials for Dravet syndrome, a severe and debilitating genetic epilepsy. Additionally, STK-002 is in the preclinical development stage for treating autosomal dominant optic atrophy. The company has also established a licensing and collaborative agreement with Acadia Pharmaceuticals Inc. to identify, develop, and market new RNA-based medicines for critical and rare genetic neurodevelopmental conditions impacting the central nervous system. Formerly known as ASOthera Pharmaceuticals, Inc., the company rebranded to Stoke Therapeutics, Inc. in May 2016. Founded in 2014, Stoke Therapeutics, Inc. maintains its headquarters in Bedford, Massachusetts.

Zen Rating

Our proven quant model uses 115 proprietary factors, including AI, to determine STOK's potential to beat the market

DSell
  • Stocks with a Zen Rating of Sell (D) had an average loss of -6.47% per year. Learn More

Zen Rating Component Grades

D
Zen Rating uses advanced AI algorithms that detect subtle patterns in market data; it anticipates future trends that point to superior stock price results.

Industry: Biotech

Industry Rating
F
STOK
Ranked
#337 of 463

Top Ranked Stocks in Industry

Name / TickerPriceZen Rating
$9.06A
$113.88A
$6.95A
View Top Biotech Stocks

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STOK News

Overview

Due Diligence Score

Industry Average (24)
You've viewed Due Diligence Score for 10/10 free stocks. Upgrade to Premium to see how STOK scored across 33 valuation, financial, forecast, performance, and dividend due diligence checks.

Due Diligence Checks

STOK is unprofitable, so we are unable to calculate its intrinsic value according to an updated version of Benjamin Graham's Formula from "The Intelligent Investor"
Below Benjamin Graham Formula Value Valuation
STOK is poor value based on its book value relative to its share price (5.9x), compared to the US Biotechnology industry average (5.46x)
P/B vs Industry Valuation
STOK is unprofitable, so we... subscribe to Premium to read more.
PEG Value Valuation
There are 30 more STOK due diligence checks available for Premium users.

Valuation

STOK price to earnings (PE)

For valuing profitable companies with steady earnings

Company
-9.38x
Industry
16.84x
Market
40.56x

STOK price to book (PB)

For valuing companies that are loss-making or have lots of physical asset

Company
5.9x
Industry
5.46x
STOK is poor value based... subscribe to Premium to read more.
P/B vs Industry Valuation

STOK's financial health

Profit margin

Revenue
$9.3M
Net Income
-$61.6M
Profit Margin
-660.8%
STOK's cash and short-term investments... subscribe to Premium to read more.
Interest Coverage Financials
STOK's profit margin has decreased... subscribe to Premium to read more.
Profit Margin Growth Financials

Assets to liabilities

Assets
$394.0M
Liabilities
$48.4M
Debt to equity
0.14
STOK's short-term assets ($322.54M) exceed... subscribe to Premium to read more.
Short-term Liabilities Financials
STOK's short-term assets ($322.54M) exceed... subscribe to Premium to read more.
Long-term Liabilities Financials
STOK's debt has increased relative... subscribe to Premium to read more.
Shrinking Debt Financials
STOK's debt to equity ratio... subscribe to Premium to read more.
Healthy Debt to Equity Financials

Cash flow

Operating
-$56.6M
Investing
$9.0M
Financing
$1.9M
STOK's cash and short-term investments... subscribe to Premium to read more.
Debt Coverage Financials

STOK vs Biotech Stocks

TickerZen RatingMarket Cap1d %P/EP/B
STOKD$2.04B-2.98%-9.38x5.90x
ZBIOD$2.04B-4.14%-3.25x8.25x
ZYMEC$2.01B-2.55%-14.00x24.96x
NBTXC$2.00B-8.70%-71.70x-20.55x
MRVIC$1.99B-8.24%-14.77x9.75x

Stoke Therapeutics Stock FAQ

What is Stoke Therapeutics's quote symbol?

(NASDAQ: STOK) Stoke Therapeutics trades on the NASDAQ under the ticker symbol STOK. Stoke Therapeutics stock quotes can also be displayed as NASDAQ: STOK.

If you're new to stock investing, here's how to buy Stoke Therapeutics stock.

What is the 52 week high and low for Stoke Therapeutics (NASDAQ: STOK)?

(NASDAQ: STOK) Stoke Therapeutics's 52-week high was $40.22, and its 52-week low was $18.80. It is currently -21.38% from its 52-week high and 68.19% from its 52-week low.

How much is Stoke Therapeutics stock worth today?

(NASDAQ: STOK) Stoke Therapeutics currently has 64,526,242 outstanding shares. With Stoke Therapeutics stock trading at $31.62 per share, the total value of Stoke Therapeutics stock (market capitalization) is $2.04B.

Stoke Therapeutics stock was originally listed at a price of $25.57 in Jun 19, 2019. If you had invested in Stoke Therapeutics stock at $25.57, your return over the last 7 years would have been 23.66%, for an annualized return of 3.08% (not including any dividends or dividend reinvestments).

How much is Stoke Therapeutics's stock price per share?

(NASDAQ: STOK) Stoke Therapeutics stock price per share is $31.62 today (as of Aug 28, 2026).

What is Stoke Therapeutics's Market Cap?

(NASDAQ: STOK) Stoke Therapeutics's market cap is $2.04B, as of Aug 30, 2026.

Market cap (market capitalization) is the total market value of a publicly traded company's outstanding shares.

Stoke Therapeutics's market cap is calculated by multiplying STOK's current stock price of $31.62 by STOK's total outstanding shares of 64,526,242.
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Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.