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NASDAQ: SION
Sionna Therapeutics Inc Stock Forecast, Predictions & Price Target

OverviewForecast
EarningsRevenueDividendOwnership

Analyst price target for SION

Based on 8 analysts offering 12 month price targets for Sionna Therapeutics Inc

Min Forecast
$38.00+5.79%
Avg Forecast
$55.00+53.12%
Max Forecast
$63.00+75.39%

Should I buy or sell SION stock?

Based on 8 analysts offering ratings for Sionna Therapeutics Inc.

Strong Buy
Strong Buy
4 analysts 50%
Buy
3 analysts 37.5%
Hold
1 analysts 12.5%
Sell
0 analysts 0%
Strong Sell
0 analysts 0%
Although SION's forecast from analysts indicates a "Strong Buy", our proven Zen Rating quant model rates SION as a "Sell". Stocks with a Zen Rating of Sell have had an average return of -4.50% per year. Learn More

Be the first to know when Wall Street analysts revise their SION stock forecasts and price targets.

SION stock forecasts by analyst

Analyst / FirmRatingActionPrice TargetUpside/DownsideDateAnalyst Color
lockedlocked$00.00+00.00%2026-05-26
lockedlocked$00.00+00.00%2026-05-20
lockedlocked$00.00+00.00%2026-05-18
lockedlocked$00.00+00.00%2026-05-13
lockedlocked$00.00+00.00%2026-05-05
Jones Trading
Top 24%
77
Strong BuyMaintains$63.00+75.39%2026-04-28
Guggenheim
Top 3%
98
Strong BuyMaintains$50.00+39.20%2026-03-03
LifeSci Capital
Top 48%
53
BuyInitiates Coverage On$60.00+67.04%2025-12-23

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Forecast return on equity

Is SION forecast to generate an efficient return?

Company
-51.56%
Industry
95.51%
Market
175.55%
SION's Return on Equity is... subscribe to Premium to read more.
Forecast High Return on Equity Forecast

Forecast return on assets

Is SION forecast to generate an efficient return on assets?

Company
-48.71%
Industry
28.06%
SION is forecast to generate... subscribe to Premium to read more.
Forecast Return on Assets vs Industry Forecast

SION earnings per share forecast

What is SION's earnings per share in the next 3 years based on estimates from 13 analysts?

Avg 1 year Forecast
-$2.65
Avg 2 year Forecast
-$2.89
Avg 3 year Forecast
-$3.30

SION revenue forecast

What is SION's revenue in the next 3 years based on estimates from 13 analysts?

Avg 1 year Forecast
$0.0
Avg 2 year Forecast
$3.1M
Avg 3 year Forecast
$3.4M

SION vs Biotech Stocks

TickerPricePrice TargetUp/downsideConsensus
SION$35.92$55.00+53.12%Strong Buy
AMLX$14.59$25.00+71.35%Strong Buy
SEPN$35.95$42.83+19.15%Strong Buy
SNDX$18.25$103.67+468.04%Strong Buy
SRPT$15.31$26.33+72.00%Hold
View Top Biotech Stocks

Sionna Therapeutics Stock Forecast FAQ

Is Sionna Therapeutics Stock a good buy in 2026, according to Wall Street analysts?

The consensus among 8 Wall Street analysts covering (NASDAQ: SION) stock is to Strong Buy SION stock.

Out of 8 analysts, 4 (50%) are recommending SION as a Strong Buy, 3 (37.5%) are recommending SION as a Buy, 1 (12.5%) are recommending SION as a Hold, 0 (0%) are recommending SION as a Sell, and 0 (0%) are recommending SION as a Strong Sell.

If you're new to stock investing, here's how to buy Sionna Therapeutics stock.

What is SION's earnings growth forecast for 2026-2028?

(NASDAQ: SION) Sionna Therapeutics's forecast annual earnings growth rate of N/A is not forecast to beat the US Biotechnology industry's average forecast earnings growth rate of 16.2%, and while it is not forecast to beat the US market's average forecast earnings growth rate of 34.65%.

Sionna Therapeutics's earnings in 2026 is -$85,565,000.On average, 13 Wall Street analysts forecast SION's earnings for 2026 to be -$119,512,924, with the lowest SION earnings forecast at -$151,768,319, and the highest SION earnings forecast at -$102,400,948. On average, 13 Wall Street analysts forecast SION's earnings for 2027 to be -$130,358,033, with the lowest SION earnings forecast at -$205,307,581, and the highest SION earnings forecast at -$93,867,536.

In 2028, SION is forecast to generate -$148,797,428 in earnings, with the lowest earnings forecast at -$249,554,904 and the highest earnings forecast at -$88,178,594.

What is SION's revenue growth forecast for 2026-2028?

(NASDAQ: SION) Sionna Therapeutics's forecast annual revenue growth rate of N/A is not forecast to beat the US Biotechnology industry's average forecast revenue growth rate of 33.61%, and while it is not forecast to beat the US market's average forecast revenue growth rate of 13.79%.

Sionna Therapeutics's revenue in 2026 is $0.On average, 13 Wall Street analysts forecast SION's revenue for 2026 to be $0, with the lowest SION revenue forecast at $0, and the highest SION revenue forecast at $0. On average, 12 Wall Street analysts forecast SION's revenue for 2027 to be $138,160,010, with the lowest SION revenue forecast at $0, and the highest SION revenue forecast at $1,422,235,395.

In 2028, SION is forecast to generate $153,511,122 in revenue, with the lowest revenue forecast at $0 and the highest revenue forecast at $1,422,235,395.

What is SION's forecast return on assets (ROA) for 2026-2029?

(NASDAQ: SION) forecast ROA is -48.71%, which is lower than the forecast US Biotechnology industry average of 28.06%.

What is SION's Price Target?

According to 8 Wall Street analysts that have issued a 1 year SION price target, the average SION price target is $55.00, with the highest SION stock price forecast at $63.00 and the lowest SION stock price forecast at $38.00.

On average, Wall Street analysts predict that Sionna Therapeutics's share price could reach $55.00 by May 26, 2027. The average Sionna Therapeutics stock price prediction forecasts a potential upside of 53.12% from the current SION share price of $35.92.

What is SION's Earnings Per Share (EPS) forecast for 2026-2028?

(NASDAQ: SION) Sionna Therapeutics's current Earnings Per Share (EPS) is -$1.92. On average, analysts forecast that SION's EPS will be -$2.65 for 2026, with the lowest EPS forecast at -$3.36, and the highest EPS forecast at -$2.27. On average, analysts forecast that SION's EPS will be -$2.89 for 2027, with the lowest EPS forecast at -$4.55, and the highest EPS forecast at -$2.08. In 2028, SION's EPS is forecast to hit -$3.30 (min: -$5.53, max: -$1.95).

What is SION's forecast return on equity (ROE) for 2026-2029?

(NASDAQ: SION) forecast ROE is -51.56%, which is considered weak.
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