NASDAQ: KPTI
Karyopharm Therapeutics Inc Earnings Dates, Reports, Calls

Karyopharm Therapeutics earnings were -$224.7M for the trailing 12 months ending Jun 30, 2026, with N/A growth year over year. The latest KPTI earnings report on Jun 30, 2026 announced Q2 2026 earnings of -$67.0M, up 199.3% from last quarter. For the last reported fiscal year 2025 ending Dec 31, 2025, KPTI reported annual earnings of -$196.0M, with 156.5% growth. The next KPTI earnings date is Nov 2, 2026.

KPTI earnings history

Current Revenue
$146.6M
Current Earnings
-$224.7M
Current Profit Margin
-153.3%

KPTI Return on Equity

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KPTI Return on Assets

Current Company
-200.9%
Current Industry
-10.2%
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Above Average Return on Assets Performance

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KPTI Return on Capital Employed

Current Company
765.61%
Current Industry
-6.7%
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Increasing Return on Capital Employed Performance

KPTI vs Biotech Stocks

TickerEBITDAEarningsY/Y EarningsEPS
KPTI-$175.30M-$224.74MN/A-$14.16
FLNA-$41.30M-$42.28MN/A-$0.87
ATYR-$59.23M-$60.81MN/A-$0.62
CRVO-$30.35M-$30.35MN/A-$3.22
LITS-$60.82M-$60.82MN/A-$2.00

KPTI earnings dates

Next earnings date
Nov 2, 2026

Karyopharm Therapeutics Earnings Reports & History FAQ

What were Karyopharm Therapeutics's earnings last quarter?

On KPTI's earnings call on Aug 13, 2026, Karyopharm Therapeutics (NASDAQ: KPTI) reported Q2 2026 earnings per share (EPS) of -$2.32, up 46.3% year over year. Total KPTI earnings for the quarter were -$67.02 million. In the same quarter last year, Karyopharm Therapeutics's earnings per share (EPS) was -$4.32.

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When does Karyopharm Therapeutics report earnings?

The next KPTI earnings call is Nov 2, 2026. Add KPTI to your watchlist to be reminded of Karyopharm Therapeutics's next earnings date.

Is Karyopharm Therapeutics profitable or losing money?

As of the last Karyopharm Therapeutics earnings report, Karyopharm Therapeutics is currently losing money. Karyopharm Therapeutics's net profit (also called net income) for the twelve months ending Jun 30, 2026 was -$224.74 million, a 81.88% increase year over year.

What was KPTI's earnings growth in the past year?

As of Karyopharm Therapeutics's earnings date in Aug 13, 2026, Karyopharm Therapeutics's earnings has grown year over year. KPTI earnings in the past year totalled -$224.74 million.

What are Karyopharm Therapeutics's earnings expectations?

The current EPS estimate for Karyopharm Therapeutics's earnings report in Nov 2, 2026 is -$1.15.
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