| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Alan J. Russell | Chief Scientific Officer | 2025-08-26 | 100,000 | $0.18 | $18.00kBuy |
| Alan J. Russell | Chief Scientific Officer | 2025-08-26 | 100,000 | $14.60 | $1.46MSell |
| Kevin Koch | President and CEO | 2025-08-12 | 7,972 | $13.39 | $106.76kSell |
| R. Michael Carruthers | Chief Financial Officer | 2025-08-12 | 1,428 | $13.39 | $19.12kSell |
| Behrad Derakhshan | Chief Business Officer | 2025-08-12 | 2,491 | $13.39 | $33.36kSell |
| Alan J. Russell | Chief Scientific Officer | 2025-08-12 | 1,907 | $13.39 | $25.54kSell |
| John R. 1. Moore | General Counsel | 2025-08-12 | 2,098 | $13.39 | $28.10kSell |
| Joanne M. Donovan | CMO | 2025-08-12 | 2,862 | $13.39 | $38.33kSell |
| R. Michael Carruthers | Chief Financial Officer | 2025-05-02 | 1,314 | $16.45 | $21.62kSell |
| Behrad Derakhshan | Chief Business Officer | 2025-05-02 | 1,691 | $16.45 | $27.82kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Orbimed Advisors LLC | 14.73% | 15,518,492 | $254.81M | Institution |
| Ra Capital Management LP | 9.40% | 9,902,633 | $162.60M | Institution |
| Baker Bros Advisors LP | 6.94% | 7,305,940 | $119.96M | Institution |
| Blackrock Inc | 6.44% | 6,781,046 | $111.34M | Institution |
| Paradigm Biocapital Advisors LP | 5.83% | 6,142,344 | $100.86M | Institution |
| Holdings A. Novo | 5.76% | 6,071,703 | $99.70M | Insider |
| Janus Henderson Group PLC | 5.22% | 5,503,349 | $90.36M | Institution |
| Novo Holdings A | 5.08% | 5,350,000 | $87.85M | Institution |
| Braidwell LP | 4.95% | 5,210,831 | $85.56M | Institution |
| Vanguard Group Inc | 4.60% | 4,841,500 | $79.50M | Institution |