| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Seth Loring Harrison | 13.57% | 8,124,773 | $35.10M | Insider |
| Bvf Inc | 10.51% | 6,293,282 | $27.19M | Institution |
| Erez Chimovits | 9.55% | 5,720,424 | $24.71M | Insider |
| Novartis Bioventures Ltd | 7.50% | 4,493,458 | $19.41M | Insider |
| Apple Tree Partners II LP | 7.04% | 4,218,641 | $18.22M | Insider |
| Apple Tree Partners II Annex LP | 5.96% | 3,568,438 | $15.42M | Insider |
| Ra Capital Management LP | 5.96% | 3,566,338 | $15.41M | Institution |
| Vanguard Group Inc | 5.54% | 3,318,383 | $14.34M | Institution |
| Blackrock Inc | 5.43% | 3,254,152 | $14.06M | Institution |
| First Light Asset Management LLC | 4.34% | 2,600,498 | $11.23M | Institution |