| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Seth Loring Harrison | 13.56% | 8,124,773 | $13.16M | Insider |
| Bvf Inc | 10.50% | 6,293,282 | $10.20M | Institution |
| Erez Chimovits | 9.54% | 5,720,424 | $9.27M | Insider |
| Novartis Bioventures Ltd | 7.50% | 4,493,458 | $7.28M | Insider |
| Apple Tree Partners II LP | 7.04% | 4,218,641 | $6.83M | Insider |
| Apple Tree Partners II Annex LP | 5.95% | 3,568,438 | $5.78M | Insider |
| Ra Capital Management LP | 5.95% | 3,566,338 | $5.78M | Institution |
| Blackrock Inc | 5.78% | 3,465,082 | $5.61M | Institution |
| Vanguard Group Inc | 5.45% | 3,267,783 | $5.29M | Institution |
| Siren LLC | 3.46% | 2,072,767 | $3.36M | Institution |