| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Steven George Hughes | Chief Medical Officer | 2025-10-22 | 2,209 | $10.16 | $22.44kBuy |
| Steven George Hughes | Chief Medical Officer | 2025-10-22 | 2,209 | $47.54 | $105.01kSell |
| Teresa McCarthy | Chief Human Resources Officer | 2025-10-15 | 20,000 | $50.15 | $1.00MSell |
| Teresa McCarthy | Chief Human Resources Officer | 2025-10-15 | 20,000 | $22.34 | $446.80kBuy |
| Eric Mosbrooker | Chief Commercial Officer | 2025-10-03 | 6,562 | $45.38 | $297.77kSell |
| Eric Mosbrooker | Chief Commercial Officer | 2025-10-03 | 6,562 | $9.05 | $59.39kBuy |
| Steven George Hughes | Chief Medical Officer | 2025-09-22 | 2,208 | $40.58 | $89.60kSell |
| Steven George Hughes | Chief Medical Officer | 2025-09-22 | 2,208 | $10.16 | $22.43kBuy |
| Teresa McCarthy | Chief Human Resources Officer | 2025-09-15 | 15,000 | $41.41 | $621.15kSell |
| Teresa McCarthy | Chief Human Resources Officer | 2025-09-15 | 15,000 | $22.34 | $335.10kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Fmr LLC | 13.43% | 16,185,791 | $1.13B | Institution |
| Price T Rowe Associates Inc | 8.97% | 10,808,727 | $754.23M | Institution |
| Janus Henderson Group PLC | 8.94% | 10,777,317 | $752.04M | Institution |
| Rtw Investments LP | 7.98% | 9,618,845 | $671.20M | Institution |
| Blackrock Inc | 7.75% | 9,336,834 | $651.52M | Institution |
| Wellington Management Group LLP | 7.67% | 9,249,690 | $645.44M | Institution |
| Vanguard Group Inc | 7.67% | 9,248,302 | $645.35M | Institution |
| Rtw Investments LP | 7.29% | 8,790,000 | $613.37M | Insider |
| Ra Capital Management LP | 6.03% | 7,266,031 | $507.02M | Institution |
| Avoro Capital Advisors LLC | 5.85% | 7,050,000 | $491.95M | Institution |