| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Steven George Hughes | Chief Medical Officer | 2025-10-22 | 2,209 | $10.16 | $22.44kBuy |
| Steven George Hughes | Chief Medical Officer | 2025-10-22 | 2,209 | $47.54 | $105.01kSell |
| Teresa McCarthy | Chief Human Resources Officer | 2025-10-15 | 20,000 | $50.15 | $1.00MSell |
| Teresa McCarthy | Chief Human Resources Officer | 2025-10-15 | 20,000 | $22.34 | $446.80kBuy |
| Eric Mosbrooker | Chief Commercial Officer | 2025-10-03 | 6,562 | $45.38 | $297.77kSell |
| Eric Mosbrooker | Chief Commercial Officer | 2025-10-03 | 6,562 | $9.05 | $59.39kBuy |
| Steven George Hughes | Chief Medical Officer | 2025-09-22 | 2,208 | $40.58 | $89.60kSell |
| Steven George Hughes | Chief Medical Officer | 2025-09-22 | 2,208 | $10.16 | $22.43kBuy |
| Teresa McCarthy | Chief Human Resources Officer | 2025-09-15 | 15,000 | $41.41 | $621.15kSell |
| Teresa McCarthy | Chief Human Resources Officer | 2025-09-15 | 15,000 | $22.34 | $335.10kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Fmr LLC | 14.33% | 21,585,984 | $1.55B | Institution |
| Janus Henderson Group PLC | 9.64% | 14,522,915 | $1.04B | Institution |
| Vanguard Group Inc | 8.77% | 13,219,759 | $946.93M | Institution |
| Rtw Investments LP | 7.55% | 11,372,829 | $814.64M | Institution |
| Wellington Management Group LLP | 6.68% | 10,065,187 | $720.97M | Institution |
| Price T Rowe Associates Inc | 6.50% | 9,787,417 | $701.07M | Institution |
| Blackrock Inc | 6.11% | 9,202,579 | $659.18M | Institution |
| Rtw Investments LP | 5.83% | 8,790,000 | $629.63M | Insider |
| Ra Capital Management LP | 5.73% | 8,641,031 | $618.96M | Institution |
| Avoro Capital Advisors LLC | 5.07% | 7,645,000 | $547.61M | Institution |