NASDAQ: DNLI
Denali Therapeutics Inc Stock

$14.55-0.38 (-2.55%)
Updated Jun 13, 2025
DNLI Price
$14.55
Fair Value Price
$0.77
Market Cap
$2.11B
52 Week Low
$10.57
52 Week High
$33.33
P/E
-5.43x
P/B
1.88x
P/S
N/A
PEG
N/A
Dividend Yield
N/A
Revenue
$0.00
Earnings
-$453.94M
Gross Margin
N/A
Operating Margin
N/A
Profit Margin
N/A
Debt to Equity
0.13
Operating Cash Flow
-$366M
Beta
1.57
Next Earnings
N/A
Ex-Dividend
N/A
Next Dividend
N/A

DNLI Overview

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutic candidates for neurodegenerative diseases in the United States. It offers leucine-rich repeat kinase 2 (LRRK2) inhibitor product candidate, including BIIB122/DNL151, a small molecule inhibitor, which is in phase I and phase Ib clinical trials for the treatment of Parkinson's disease. The company also develops DNL310 that is in Phase I/II clinical trials for the treatment of hunter syndrome; DNL343, which is in phase 1 clinical trial the treatment of amyotrophic lateral sclerosis (ALS); AR443820/DNL788 completed a phase I clinical trial for the treatment of ALS, multiple sclerosis (MS), and Alzheimer's disease; and SAR443122/DNL758, which is in phase II clinical trial for the treatment of cutaneous lupus erythematosus. It has collaboration agreement with Takeda Pharmaceutical Company, Genentech, Inc., Sanofi, F-star Gamma Limited, F-star Biotechnologische Forschungs-Und Entwicklungsges M.B.H, F-star Biotechnology Limited, SIRION Biotech GmbH, Genzyme Corporation, Harvard University, the Michael J. Fox Foundation, and Centogene; and a research and option agreement with Secarna Pharmaceuticals GmbH & Co. KG. to develop antisense therapies in the field of neurodegenerative diseases. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

Zen Rating

Our proven quant model uses 115 proprietary factors, including AI, to determine DNLI's potential to beat the market

FStrong Sell
  • Stocks with a Zen Rating of Strong Sell (F) had an average loss of -8.02% per year. Learn More

Zen Rating Component Grades

D
Zen Rating uses advanced AI algorithms that detect subtle patterns in market data; it anticipates future trends that point to superior stock price results.

Industry: Biotech

Industry Rating
F
DNLI
Ranked
#403 of 464

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Overview

Due Diligence Score

Industry Average (24)
You've viewed Due Diligence Score for 10/10 free stocks. Upgrade to Premium to see how DNLI scored across 33 valuation, financial, forecast, performance, and dividend due diligence checks.

Due Diligence Checks

DNLI ($14.55) is overvalued by 1,795.47% relative to our estimate of its Fair Value price of $0.77 based on Discounted Cash Flow (DCF) modelling
Below Fair Value Valuation
DNLI ($14.55) is not significantly undervalued (1,795.47%) relative to our estimate of its Fair Value price of $0.77 based on Discounted Cash Flow (DCF) modelling, when including a healthy margin of safety
Significantly Below Fair Value Valuation
DNLI is unprofitable, so we... subscribe to Premium to read more.
Below Benjamin Graham Formula Value Valuation
There are 30 more DNLI due diligence checks available for Premium users.

Valuation

DNLI fair value

Fair Value of DNLI stock based on Discounted Cash Flow (DCF)

Price
$14.55
Fair Value
$0.77
Overvalued by
1,795.47%
DNLI ($14.55) is overvalued by... subscribe to Premium to read more.
Below Fair Value Valuation
DNLI ($14.55) is not significantly... subscribe to Premium to read more.
Significantly Below Fair Value Valuation
DNLI is unprofitable, so we... subscribe to Premium to read more.
Below Benjamin Graham Formula Value Valuation

DNLI price to earnings (PE)

For valuing profitable companies with steady earnings

Company
-5.43x
Industry
-108.97x
Market
31.36x

DNLI price to book (PB)

For valuing companies that are loss-making or have lots of physical asset

Company
1.88x
Industry
4.66x
DNLI is good value based... subscribe to Premium to read more.
P/B vs Industry Valuation

DNLI's financial health

Profit margin

Revenue
$0.0
Net Income
-$133.0M
Profit Margin
0%
DNLI's cash burn is expected... subscribe to Premium to read more.
Interest Coverage Financials

Assets to liabilities

Assets
$1.3B
Liabilities
$148.7M
Debt to equity
0.13
DNLI's short-term assets ($878.64M) exceed... subscribe to Premium to read more.
Short-term Liabilities Financials
DNLI's short-term assets ($878.64M) exceed... subscribe to Premium to read more.
Long-term Liabilities Financials
DNLI's debt relative to shareholder... subscribe to Premium to read more.
Shrinking Debt Financials
DNLI's debt to equity ratio... subscribe to Premium to read more.
Healthy Debt to Equity Financials

Cash flow

Operating
-$131.5M
Investing
$18.7M
Financing
-$3.8M
DNLI's cash and short-term investments... subscribe to Premium to read more.
Debt Coverage Financials

DNLI vs Biotech Stocks

TickerZen RatingMarket Cap1d %P/EP/B
DNLIF$2.11B-2.51%-5.43x1.88x
VCELC$2.15B+0.45%853.40x7.27x
VCYTB$2.07B-0.94%61.49x1.73x
KNSAB$2.07B+2.06%-117.92x4.51x
BCRXA$2.17B-0.29%-39.88x-4.80x

Denali Therapeutics Stock FAQ

What is Denali Therapeutics's quote symbol?

(NASDAQ: DNLI) Denali Therapeutics trades on the NASDAQ under the ticker symbol DNLI. Denali Therapeutics stock quotes can also be displayed as NASDAQ: DNLI.

If you're new to stock investing, here's how to buy Denali Therapeutics stock.

What is the 52 week high and low for Denali Therapeutics (NASDAQ: DNLI)?

(NASDAQ: DNLI) Denali Therapeutics's 52-week high was $33.33, and its 52-week low was $10.57. It is currently -56.35% from its 52-week high and 37.65% from its 52-week low.

How much is Denali Therapeutics stock worth today?

(NASDAQ: DNLI) Denali Therapeutics currently has 145,276,299 outstanding shares. With Denali Therapeutics stock trading at $14.55 per share, the total value of Denali Therapeutics stock (market capitalization) is $2.11B.

Denali Therapeutics stock was originally listed at a price of $21.45 in Dec 8, 2017. If you had invested in Denali Therapeutics stock at $21.45, your return over the last 7 years would have been -32.17%, for an annualized return of -5.39% (not including any dividends or dividend reinvestments).

How much is Denali Therapeutics's stock price per share?

(NASDAQ: DNLI) Denali Therapeutics stock price per share is $14.55 today (as of Jun 13, 2025).

What is Denali Therapeutics's Market Cap?

(NASDAQ: DNLI) Denali Therapeutics's market cap is $2.11B, as of Jun 15, 2025.

Market cap (market capitalization) is the total market value of a publicly traded company's outstanding shares.

Denali Therapeutics's market cap is calculated by multiplying DNLI's current stock price of $14.55 by DNLI's total outstanding shares of 145,276,299.
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Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.