| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Mario Alberto Accardi | Chief Executive Officer | 2026-05-01 | 604 | $39.42 | $23.81kSell |
| Karen M. Anderson | Chief People Officer | 2026-03-26 | 41,076 | $8.01 | $329.02kBuy |
| Gregory M. Weinhoff | Chief Business Officer | 2026-03-26 | 23,998 | $30.00 | $719.94kSell |
| Gregory M. Weinhoff | Chief Business Officer | 2026-03-26 | 23,998 | $3.85 | $92.39kBuy |
| Karen M. Anderson | Chief People Officer | 2026-03-26 | 41,076 | $30.12 | $1.24MSell |
| Karen M. Anderson | Chief People Officer | 2026-03-17 | 10,043 | $28.10 | $282.21kSell |
| Karen M. Anderson | Chief People Officer | 2026-03-17 | 10,043 | $4.01 | $40.27kBuy |
| Karen M. Anderson | Chief People Officer | 2026-03-16 | 64,768 | $28.21 | $1.83MSell |
| Karen M. Anderson | Chief People Officer | 2026-03-16 | 64,768 | $4.01 | $259.72kBuy |
| Karen M. Anderson | Chief People Officer | 2026-03-13 | 109,398 | $4.01 | $438.69kBuy |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Medicxi Ventures Management Jersey Ltd | 12.90% | 19,963,157 | $798.93M | Institution |
| Avoro Capital Advisors LLC | 7.39% | 11,430,455 | $457.45M | Institution |
| Index Venture Life Associates VI Ltd | 6.44% | 9,961,789 | $398.67M | Institution |
| Gap Bermuda Ltd | 6.26% | 9,681,818 | $387.47M | Insider |
| Adage Capital Partners GP LLC | 5.77% | 8,925,010 | $357.18M | Institution |
| Pentwater Capital Management LP | 5.28% | 8,170,000 | $326.96M | Institution |
| Fmr LLC | 4.43% | 6,852,047 | $274.22M | Institution |
| Ecor1 Capital LLC | 3.88% | 6,000,000 | $240.12M | Institution |
| Perceptive Advisors LLC | 3.40% | 5,258,903 | $210.46M | Institution |
| Capital World Investors | 3.12% | 4,832,548 | $193.40M | Institution |