| Name | Role | Date | Shares | Price | Value | 
|---|---|---|---|---|---|
| Claire Mazumdar | Chief Executive Officer | 2025-10-16 | 24,103 | $18.83 | $453.76kSell | 
| Claire Mazumdar | Chief Executive Officer | 2025-10-16 | 24,103 | $3.79 | $91.35kBuy | 
| Claire Mazumdar | Chief Executive Officer | 2025-10-15 | 13,289 | $3.79 | $50.37kBuy | 
| Ryan Cohlhepp | President and COO | 2025-10-15 | 4,500 | $18.16 | $81.70kSell | 
| Claire Mazumdar | Chief Executive Officer | 2025-10-15 | 13,289 | $18.84 | $250.39kSell | 
| Ryan Cohlhepp | President and COO | 2025-10-15 | 8,000 | $3.79 | $30.32kBuy | 
| Ryan Cohlhepp | President and COO | 2025-10-15 | 8,000 | $18.16 | $145.24kSell | 
| Claire Mazumdar | Chief Executive Officer | 2025-10-13 | 11,445 | $18.92 | $216.55kSell | 
| Claire Mazumdar | Chief Executive Officer | 2025-10-13 | 11,445 | $3.79 | $43.38kBuy | 
| David Raben | Chief Medical Officer | 2025-10-09 | 22,000 | $18.45 | $405.90kSell | 
| Name | Hold | Shares | Value | Type | 
|---|---|---|---|---|
| Ra Capital Management LP | 12.75% | 6,955,993 | $110.46M | Institution | 
| Kiran Mazumdarshaw | 11.54% | 6,297,854 | $100.01M | Insider | 
| Biocon Ltd | 10.12% | 5,523,897 | $87.72M | Insider | 
| Siren LLC | 9.56% | 5,216,969 | $82.85M | Institution | 
| Vestal Point Capital LP | 9.16% | 5,000,000 | $79.40M | Institution | 
| Red Tree Management LLC | 5.81% | 3,170,509 | $50.35M | Institution | 
| Tpg GP A LLC | 5.52% | 3,010,425 | $47.81M | Institution | 
| Ra Capital Management LP | 4.86% | 2,652,575 | $42.12M | Insider | 
| Fmr LLC | 4.65% | 2,538,404 | $40.31M | Institution | 
| Deep Track Capital LP | 4.45% | 2,426,657 | $38.54M | Institution |