| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Naseem Zojwalla | Chief Medical Officer | 2025-12-23 | 99,509 | $27.66 | $2.75MSell |
| Naseem Zojwalla | Chief Medical Officer | 2025-12-23 | 50,000 | $7.02 | $351.00kBuy |
| Naseem Zojwalla | Chief Medical Officer | 2025-12-22 | 100,000 | $28.04 | $2.80MSell |
| Naseem Zojwalla | Chief Medical Officer | 2025-12-22 | 7,182 | $7.02 | $50.42kBuy |
| Naseem Zojwalla | Chief Medical Officer | 2025-12-22 | 42,818 | $15.25 | $652.97kBuy |
| Ian T. Clark | Director | 2025-12-19 | 29,904 | $28.83 | $862.13kSell |
| Ian T. Clark | Director | 2025-12-19 | 193,056 | $29.71 | $5.74MSell |
| Ian T. Clark | Director | 2025-12-19 | 41,840 | $30.48 | $1.28MSell |
| David C. Myles | CH. DISCOV. NON-CLIN DEV OFF | 2025-12-19 | 43,729 | $30.40 | $1.33MSell |
| David C. Myles | CH. DISCOV. NON-CLIN DEV OFF | 2025-12-19 | 6,046 | $31.39 | $189.78kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Bain Capital Life Sciences Investors LLC | 10.92% | 7,500,000 | $196.73M | Insider |
| Bain Capital Life Sciences Investors LLC | 9.97% | 6,843,954 | $179.52M | Institution |
| Paradigm Biocapital Advisors LP | 9.90% | 6,794,172 | $178.21M | Institution |
| Paradigm Biocapital Advisors LP | 8.02% | 5,503,600 | $144.36M | Insider |
| Bvf Inc | 7.71% | 5,295,893 | $138.91M | Institution |
| Blackrock Inc | 6.88% | 4,726,394 | $123.97M | Institution |
| Janus Henderson Group PLC | 5.22% | 3,585,849 | $94.06M | Institution |
| Deep Track Capital LP | 5.05% | 3,470,172 | $91.02M | Institution |
| Cormorant Asset Management LP | 4.76% | 3,270,544 | $85.79M | Insider |
| Logos Global Management LP | 4.67% | 3,208,875 | $84.17M | Institution |